Results 131 to 140 of about 55,979 (304)

Variations in “Functional Site” Residues and Classification of Three-Finger Neurotoxins in Snake Venoms

Toxins
Three-finger toxins (3FTxs) are the largest group of nonenzymatic toxins found in snake venoms. Among them, neurotoxins that target nicotinic acetylcholine receptors are the most well-studied ligands.
R. Manjunatha Kini, Cho Yeow Koh
doaj   +1 more source

Smoking effects on root coverage outcomes between 3 and 12 months: A prospective cohort study

Journal of Periodontology, EarlyView.
Abstract Background This study aimed to evaluate the impact of smoking on root coverage outcomes, comparing healing responses at 3–12 months following coronally advanced flap with a connective tissue graft (CAF+CTG). Methods This prospective cohort study included 27 participants (13 smokers, 14 non‐smokers) who required root coverage for a single Cairo
Hande Has‐Elci, Duygu Taş, Zeliha Güney, Merve Atak, Sivge Kurgan, Muhittin A. Serdar, Dimitris N. Tatakis   +6 more
wiley   +1 more source

Macronutrient and micronutrient profiles of meat types: insights into human health and diet

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Despite considerable advances in global health and nutrition, emerging challenges such as population growth, climate change, and limited natural resources continue to threaten food security. Meat remains an essential component of the human diet, supplying high‐quality proteins, essential amino acids, lipids, vitamins, and minerals necessary ...
Özgül Anitaş, Serap Göncü, Fatma Hepsağ, Nazan Koluman, Yesim Ozogul   +4 more
wiley   +1 more source

Nicotinic acetylcholine receptors

Scholarpedia, 2008
Pierre-Jean Corringer, Jean-Pierre Changeux   +1 more
openaire   +1 more source

Cannabidiol as a modulator of α7 nicotinic receptors. [PDF]

Cell Mol Life Sci, 2022
Chrestia JF, Esandi MDC, Bouzat C.
europepmc   +1 more source

Philanthotoxin analogues that selectively inhibit ganglionic nicotinic acetylcholine receptors with exceptional potency

, 2019
Philanthotoxin-433 (PhTX-433) is an active component of the venom from the Egyptian digger wasp, Philanthus triangulum. PhTX-433 non-selectively inhibits several excitatory ligand-gated ion channels, and we recently showed that its synthetic analogue ...
Kachel, Hamid S., Mellor, Ian R., Franzyk, Henrik   +2 more
core   +1 more source

PDCD5 Contributes to Airway Epithelial Cell Damage via Mitochondrial Pathway and Participates in COPD Pathogenesis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Airway epithelial injury plays a critical role in the pathogenesis of chronic obstructive pulmonary disease (COPD). Mitochondrial dysfunction is implicated in this injury, while the underlying mechanism remains incompletely understood. RNA sequencing was conducted to identify key genes involved in mitochondrial dysfunction in airway epithelial
Hu Shan, Rui Zhang, Yu‐er Li, Rui Li, Shao‐bo Ge, Jin Liu, Shi‐yuan Yao, Xia Yang, Tao Zhang, Ming Zhang   +9 more
wiley   +1 more source

Human neuronal nicotinic receptors

, 1997
Nicotine is a very widely used drug of abuse, which exerts a number of neurovegetative, behavioural and psychological effects by interacting with neuronal nicotinic acetylcholine receptors (NAChRs).
F. Clementi, C. Gotti, D. Fornasari
core   +1 more source

Knowledge Gaps, Treatment Preferences, and Unmet Clinical Needs Among Patients With Inflammatory Bowel Disease: A Cross‐Sectional Study

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study utilized a cross‐sectional survey via a structured questionnaire to evaluate disease‐related knowledge, treatment preferences, and unmet needs among 200 adults with confirmed inflammatory bowel disease (IBD) at a tertiary referral center.
Yi‐Chen Wu, Chien‐Ming Chen, Tony Kou, Tai‐Di Chen, Ming‐Jung Meng, Chen‐Wang Chang, Jen‐Wei Chou, Tien‐Yu Huang, Cheng‐Tang Chiu, Yu‐Bin Pan, Puo‐Hsien Le, Ming‐Yao Su   +11 more
wiley   +1 more source

Nicotinic acetylcholine receptors in pain modulation

Frontiers in Pharmacology
Chronic pain is widely recognized as a major global health problem that affects approximately one-fifth of the adult population and is associated with significant physical, psychological, and socioeconomic burden.
Junya Cheng, Junliang Chang, Shuai Li
doaj   +1 more source