Results 241 to 250 of about 91,243 (276)

The role of nicotinic receptors in SARS-CoV-2 receptor ACE2 expression in intestinal epithelia

, 2020
Hove ASt, Brinkman DJ, Yim AYL, Verseijden C, Hakvoort TB, Admiraal I, Welting O, Hamersveld PHv, Sinniger V, Bonaz B, Luyer MD, de Jonge WJ.   +11 more
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Schizophrenia and Nicotinic Receptors

Harvard Review of Psychiatry, 1994
Patients with schizophrenia often cannot respond to important features of their environment and filter out irrelevant stimuli. This dysfunction could be related to an underlying defect in inhibition--i.e., the brain's ability to alter its sensitivity to repeated stimuli. One of the neuronal mechanisms responsible for such inhibitory gating involves the
Robert Freedman, Lawrence E. Adler, Paula Bickford, William Byerley, Hilary Coon, Munro C. Cullum, Jay M. Griffith, Josette G. Harris, Sherry Leonard, Christine Miller, Marina Myles-Worsley, Herbert T. Nagamoto, Greg Rose, Merilyne Waldo   +13 more
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Human neuronal nicotinic receptors

Progress in Neurobiology, 1997
Nicotine is a very widely used drug of abuse, which exerts a number of neurovegetative, behavioural and psychological effects by interacting with neuronal nicotinic acetylcholine receptors (NAChRs). These receptors are distributed widely in human brain and ganglia, and form a family of ACh-gated ion channels of different subtypes, each of which has a ...
C. Gotti, D. Fornasari, F. Clementi
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The Nicotinic Receptor Genes

Clinical Neuropharmacology, 1991
The causative factor(s) of Alzheimer's disease (AD) are presently unknown. However, it has been shown that the number as well as the fraction of high- to low-affinity nicotine binding sites is altered in patients suffering from this disease. This finding, along with the identification of seven genes which code for nicotinic receptors expressed in the ...
S. Heinemann, J. Boulter, J. Connolly, E. Deneris, R. Duvoisin, M. Hartley, I. Hermans-Borgmeyer, M. Hollmann, A. OʼShea-Greenfield, R. Papke, S. R ogers, J. Patrick   +11 more
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Nicotinic Acetylcholine Receptors

2003
Publisher Summary This chapter deals with nicotinic acetylcholine receptors. Nicotinic acetylcholine receptors (nAChRs) are cholinergic receptors that form ligand-gated ion channels in the plasma membranes of certain neurons and on the postsynaptic side of the neuromuscular junction. As ionotropic receptors, nAChRs are directly linked to ion channels
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Nicotinic receptors and schizophrenia

Current Medical Research and Opinion, 2004
The incidence of smoking is very high in non-schizophrenic subjects presenting various psychiatric disorders (35 to 54%). However, the incidence of smoking is extremely high in schizophrenic patients: 80% to 90%, versus 25% to 30% of the general population. Various studies have demonstrated that the use of tobacco transiently restores the schizophrenic
Nadège, Ripoll, Marie, Bronnec, Michel, Bourin   +2 more
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Nicotine, Brain Nicotinic Receptors, and Neuropsychiatric Disorders

Archives of Medical Research, 2000
Neuronal nicotinic acetylcholine receptors (nAChRs) represent a large family of ligand-gated cation channels with diverse structures and properties. In contrast to the muscular nAChRs, the physiological functions of neuronal nAChRs are not well defined to date.
S, Mihailescu, R, Drucker-Colín
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Presynaptic nicotinic ACh receptors

Trends in Neurosciences, 1997
Nicotinic ACh (nACh) receptors in the CNS are composed of a diverse array of subunits and have a range of pharmacological properties. However, despite the fact that they are ligand-gated cation channels, their physiological functions have not been determined.
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Nicotine and Nicotinic Receptor Involvement in Neuropsychiatric Disorders

Current Topics in Medicinal Chemistry, 2004
Advances in the understanding of the neurobiology of the nicotinic receptor have started to be matched by an appreciation of the potential role of these receptors in a variety of neuropsychiatric disorders. While alterations in nicotinic receptor number and/or function have been associated with such conditions as Alzheimer's disease for several years ...
Paul, Newhouse, Abhay, Singh, Alexandra, Potter   +2 more
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Nicotine and Nicotinic Receptors; Relevance to Parkinson’s Disease

NeuroToxicology, 2002
The development of nicotinic agonists for therapy in neurodegenerative disorders such as Parkinson's disease is an area currently receiving considerable attention. The rationale for such work stems from findings that reveal a loss of nicotinic receptors in Parkinson's disease brains.
Maryka, Quik, Jennifer M, Kulak
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