Results 251 to 260 of about 597,674 (298)

Nicotinic receptors in sensory ganglia

Brain Research, 1980
Stephen Hunt, Jakob Schmidt
exaly   +3 more sources

Nicotine and Nicotinic Receptor Involvement in Neuropsychiatric Disorders

Current Topics in Medicinal Chemistry, 2004
Advances in the understanding of the neurobiology of the nicotinic receptor have started to be matched by an appreciation of the potential role of these receptors in a variety of neuropsychiatric disorders. While alterations in nicotinic receptor number and/or function have been associated with such conditions as Alzheimer's disease for several years ...
Paul, Newhouse, Abhay, Singh, Alexandra, Potter   +2 more
openaire   +2 more sources

Structure of Neuronal Nicotinic Receptors

2015
Nicotinic acetylcholine receptors (nAChRs) are a critical component of the brain's cholinergic neurotransmission system that modulates important physiological processes and whose dysfunction has been observed in patients with neurodegenerative diseases and mental illness.
Fasoli F, Gotti C
openaire   +3 more sources

Nicotine and Nicotinic Receptors; Relevance to Parkinson’s Disease

NeuroToxicology, 2002
The development of nicotinic agonists for therapy in neurodegenerative disorders such as Parkinson's disease is an area currently receiving considerable attention. The rationale for such work stems from findings that reveal a loss of nicotinic receptors in Parkinson's disease brains.
Maryka, Quik, Jennifer M, Kulak
openaire   +2 more sources

Effect of nicotine and nicotinic receptors on anxiety and depression

Neuroreport, 2002
Nicotine has been shown to have effects on anxiety and depression in both human and animal studies. These studies suggest that nicotinic acetylcholine receptors (nAChRs) can modulate the function of pathways involved in stress response, anxiety and depression in the normal brain, and that smoking can result in alterations of anxiety level and mood. The
Marina R, Picciotto, Darlene H, Brunzell, Barbara J, Caldarone   +2 more
openaire   +2 more sources

Nicotine, Brain Nicotinic Receptors, and Neuropsychiatric Disorders

Archives of Medical Research, 2000
Neuronal nicotinic acetylcholine receptors (nAChRs) represent a large family of ligand-gated cation channels with diverse structures and properties. In contrast to the muscular nAChRs, the physiological functions of neuronal nAChRs are not well defined to date.
S, Mihailescu, R, Drucker-Colín
openaire   +2 more sources

Nicotinic Acetylcholine Receptors

2003
Publisher Summary This chapter deals with nicotinic acetylcholine receptors. Nicotinic acetylcholine receptors (nAChRs) are cholinergic receptors that form ligand-gated ion channels in the plasma membranes of certain neurons and on the postsynaptic side of the neuromuscular junction. As ionotropic receptors, nAChRs are directly linked to ion channels
openaire   +2 more sources

Nicotinic Receptors and Attention

2015
Facilitation of different attentional functions by nicotinic acetylcholine receptor (nAChR) agonists may be of therapeutic potential in disease conditions such as Alzheimer's disease or schizophrenia. For this reason, the neuronal mechanisms underlying these effects have been the focus of research in humans and in preclinical models.
openaire   +2 more sources

Nicotinic receptors and Parkinson's disease

European Journal of Pharmacology, 2000
Accumulating evidence indicates that nicotinic receptors play a role in basal ganglia function. Furthermore, nicotine administration may be neuroprotective in animal models of nigrostriatal degeneration, while cigarette smoking is inversely correlated with Parkinson's disease.
M, Quik, G, Jeyarasasingam
openaire   +2 more sources

Human neuronal nicotinic receptors

Progress in Neurobiology, 1997
Nicotine is a very widely used drug of abuse, which exerts a number of neurovegetative, behavioural and psychological effects by interacting with neuronal nicotinic acetylcholine receptors (NAChRs). These receptors are distributed widely in human brain and ganglia, and form a family of ACh-gated ion channels of different subtypes, each of which has a ...
C. Gotti, D. Fornasari, F. Clementi
openaire   +3 more sources