Results 251 to 260 of about 55,979 (304)

Elevated lymphoma risk in patients with chronic pruritus and chronic prurigo

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Chronic pruritus (CP) and chronic prurigo (CPG, including prurigo nodularis) are prevalent, debilitating diseases with diverse comorbidities, including malignancies. This retrospective cohort study evaluated the prevalence and risk of lymphoma in CP and CPG patients, including key risk factors, and sex‐ and ancestry ...
Svenja Royeck, Henning Olbrich, Steffen Koschmieder, Claudia Zeidler, Felix Witte, Konstantin Agelopoulos, Henning Wiegmann, Michael Storck, Johannes Benedict Oehm, Ralf J. Ludwig, Sonja Ständer   +10 more
wiley   +1 more source

Rates of, Reasons for, and Reactions to Discontinuation of GLP‐1 Receptor Agonists: A Narrative Review

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT GLP‐1RAs are increasingly used for their glucose‐lowering and weight‐management effects, but many patients discontinue them. In this narrative review we aim to review real‐world, quantitative and qualitative GLP‐1RA discontinuation, adherence, and persistence evidence as it aligns with an established conceptual framework for understanding ...
Henry D. Heisey, L. Parker Gregg, Christopher D. Verrico, Dennis T. Villareal, Terri L. Fletcher   +4 more
wiley   +1 more source

What Is a Clinically Meaningful Change in Diabetes Distress? Findings for Diabetes Care and Research From the SFDT1 Cohort

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Diabetes distress (DD) is common and evolves heterogeneously over time. We aimed to estimate minimal clinically important differences (MCID) for the Problem Areas in Diabetes (PAID) scale and its sub‐dimensions and to identify predictors of worsening over 1 year in people with type 1 diabetes (PwT1D).
Dulce Canha, Jean‐Pierre Riveline, Fatima Kazanlieva, Gloria A. Aguayo, Charline Bour, Bruno Vergès, Pierre‐Yves Benhamou, Michaël Joubert, Fawaz Alzaid, Emmanuel Cosson, Guy Fagherazzi   +10 more
wiley   +1 more source

The role of nicotinic receptors in SARS-CoV-2 receptor ACE2 expression in intestinal epithelia

, 2020
Hove ASt, Brinkman DJ, Yim AYL, Verseijden C, Hakvoort TB, Admiraal I, Welting O, Hamersveld PHv, Sinniger V, Bonaz B, Luyer MD, de Jonge WJ.   +11 more
europepmc   +1 more source

Nicotinic receptors in wonderland

Trends in Biochemical Sciences, 2001
The structure of a soluble homopentameric homologue of the N-terminal extracellular domain of the nicotinic acetylcholine (ACh) receptor has recently been determined at the atomic level.
Thomas Grutter, Jean-Pierre Changeux
exaly   +2 more sources

Some of the next articles are maybe not open access.

Related searches:

Nicotinic receptors and schizophrenia

Current Medical Research and Opinion, 2004
The incidence of smoking is very high in non-schizophrenic subjects presenting various psychiatric disorders (35 to 54%). However, the incidence of smoking is extremely high in schizophrenic patients: 80% to 90%, versus 25% to 30% of the general population. Various studies have demonstrated that the use of tobacco transiently restores the schizophrenic
Michel Bourin
exaly   +3 more sources

Schizophrenia and Nicotinic Receptors

Harvard Review of Psychiatry, 1994
Patients with schizophrenia often cannot respond to important features of their environment and filter out irrelevant stimuli. This dysfunction could be related to an underlying defect in inhibition--i.e., the brain's ability to alter its sensitivity to repeated stimuli. One of the neuronal mechanisms responsible for such inhibitory gating involves the
Robert Freedman, Lawrence E. Adler, Paula Bickford, William Byerley, Hilary Coon, Munro C. Cullum, Jay M. Griffith, Josette G. Harris, Sherry Leonard, Christine Miller, Marina Myles-Worsley, Herbert T. Nagamoto, Greg Rose, Merilyne Waldo   +13 more
openaire   +2 more sources

The Nicotinic Receptor Genes

Clinical Neuropharmacology, 1991
The causative factor(s) of Alzheimer's disease (AD) are presently unknown. However, it has been shown that the number as well as the fraction of high- to low-affinity nicotine binding sites is altered in patients suffering from this disease. This finding, along with the identification of seven genes which code for nicotinic receptors expressed in the ...
S. Heinemann, J. Boulter, J. Connolly, E. Deneris, R. Duvoisin, M. Hartley, I. Hermans-Borgmeyer, M. Hollmann, A. OʼShea-Greenfield, R. Papke, S. R ogers, J. Patrick   +11 more
openaire   +2 more sources

Structure of Neuronal Nicotinic Receptors

2015
Nicotinic acetylcholine receptors (nAChRs) are a critical component of the brain's cholinergic neurotransmission system that modulates important physiological processes and whose dysfunction has been observed in patients with neurodegenerative diseases and mental illness.
Fasoli F, Gotti C
openaire   +3 more sources

Nicotine and Nicotinic Receptor Involvement in Neuropsychiatric Disorders

Current Topics in Medicinal Chemistry, 2004
Advances in the understanding of the neurobiology of the nicotinic receptor have started to be matched by an appreciation of the potential role of these receptors in a variety of neuropsychiatric disorders. While alterations in nicotinic receptor number and/or function have been associated with such conditions as Alzheimer's disease for several years ...
Paul, Newhouse, Abhay, Singh, Alexandra, Potter   +2 more
openaire   +2 more sources