Results 81 to 90 of about 757 (176)

The Role of Macrocyclic Compounds as Supramolecular Drug Delivery Systems: A-Review [PDF]

open access: yes
In recent decades, significant advances in the development of drug delivery systems have unlocked new possibilities for enhancing therapeutic efficacy. Among the diverse range of innovative materials, macrocyclic-based supramolecular systems have emerged
Nursofia, Yesi   +2 more
core   +2 more sources

Recent advances in the chemistry of 1,1’-bis(ortho-carborane) [PDF]

open access: yes, 2016
Chemistry of 1,1'-bis(ortho-carborane) is rapidly developing during the last years when convenient method of itssynthesis was elaborated. Here we review the recent progress in this field with main imphasis on synthesis of 1,1'-bis(ortho-carborane) based ...
Sivaev, Igor B.
core   +2 more sources

The Preparation of Aryl-Carboranes and Re-Metallocarboranes as Anti-Estrogens [PDF]

open access: yes, 2005
The estrogen receptor (ER) plays an integral role in the proliferation of hormone dependent breast cancer. Recently a number of organometallic compounds and closocarboranes, which demonstrate affinity for the estrogen receptor, were prepared as novel ...
Chankalal, Raymond
core  

Development of Novel Tumor-Targeted Compounds for Boron Neutron Capture Therapy [PDF]

open access: yes, 2019
Glioblastoma multiforme (GBM) represents the most common primary brain tumor among adults. Despite surgical resection and aggressive chemoradiotherapy regimens, the current 2- and 5-year survival rates are only 27% and 9.8%, respectively.
Luderer, Micah John
core   +1 more source

Combining BNCT with carbonic anhydrase inhibition for mesothelioma treatment: Synthesis, in vitro, in vivo studies of ureidosulfamido carboranes [PDF]

open access: yes
Mesothelioma is a malignant neoplasm of mesothelial cells caused by exposure to asbestos. The average survival time after diagnosis is usually nine/twelve months.
Alberti, Diego   +8 more
core   +1 more source

Synthesis, Behavior, and Applications of Molecules with Redox-Switchable Properties [PDF]

open access: yes, 2019
Molecules with reversible, redox-switchable properties have potential application in many fields, including catalysis, electronics, waste remediation, and energy storage.
Hunt, Camden C
core  

Kvantově chemické pojetí návrhu léčiv [PDF]

open access: yes, 2016
Computational approaches have become an established and valuable component of pharmaceutical research. Computer-aided drug design aims to reduce the time and cost of the drug development and also to bring deeper insight into the inhibitor binding to its ...
Pecina, Adam
core  

Adventures of Redox-Switchable Phosphine Oxide o-Carboranes: Coordination and Selective Capture of Metals Critical for Energy Conversion [PDF]

open access: yes
Countdown clocks in major cities like Berlin, New York, and Seoul highlight the urgent need to keep global warming below 1.5 ºC within the next five years to prevent irreversible damage to our climate. To meet climate goals, integrating low-carbon energy
Benhaim, Hila Sophia
core  

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