Cellular and physiological consequences of decreased Niemann-Pick type C1 gene expression
Disertační práce se snaží objasnit zda fyziologické snížení exprese NPC1 genu/proteinu mění transport a rovnováhu cholesterolu původem z nízko-denzitních lipoproteinů (LDL-cholesterol) v lidských fibroblastech.
Jelínek, David
core +1 more source
Potential function of hepatic Niemann-Pick C1-like 1: cholesterol homeostasis regulation of the canalicular lipid bilayer membrane. [PDF]
Chen H, Mo P, Xu G.
europepmc +1 more source
Epigenetic modulation of intestinal cholesterol transporter Niemann-Pick C1-like 1 (NPC1L1) gene expression by DNA methylation. [PDF]
Malhotra P +8 more
europepmc +1 more source
Ezetimibe inhibits hepatic Niemann-Pick C1-Like 1 to facilitate macrophage reverse cholesterol transport in mice. [PDF]
Xie P +9 more
europepmc +1 more source
Therapeutic Interventions in Niemann-Pick Disease Type C: A Systematic Review of Clinical Outcomes and Safety. [PDF]
Nafees Z +3 more
europepmc +1 more source
Niemann-Pick C1-Like 1 protein: Another target for treatment of dyslipidemia? Evidence from the Myocardial Infarction Genetic Consortium and IMPROVE-IT trials. [PDF]
Hassan M.
europepmc +1 more source
Codon-optimized <i>Npc1</i> mRNA corrects Niemann-Pick type C1 disease phenotypes <i>in vitro</i> and <i>in vivo</i>. [PDF]
Koufer ER +17 more
europepmc +1 more source
Proteomic Signatures in Neuronal and Glial Cell Models of Niemann-Pick Disease Type C. [PDF]
Wagner OC +7 more
europepmc +1 more source
The Melon Sterol Transporter Niemann-Pick C1 Protein Is a New Interactor of <i>Cucumber mosaic virus</i> Movement Protein. [PDF]
Real N +5 more
europepmc +1 more source
Site-specific cholesterol depletion therapy for gastric cancer. [PDF]
Kavrakova S +5 more
europepmc +1 more source

