Results 41 to 50 of about 66,702 (306)

Clinical periodontal diagnosis

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi, Andrea Roccuzzo, Jean‐Claude Imber, Alexandra Stähli, Björn Klinge, Niklaus P. Lang   +5 more
wiley   +1 more source

Colon cancer cell-derived 12(S)-HETE induces the retraction of cancer-associated fibroblast via MLC2, RHO/ROCK and Ca2+ signalling [PDF]

, 2016
Retraction of mesenchymal stromal cells supports the invasion of colorectal cancer cells (CRC) into the adjacent compartment. CRC-secreted 12(S)-HETE enhances the retraction of cancer-associated fibroblasts (CAFs) and therefore, 12(S)-HETE may enforce ...
Bago-Horvath, Zsuzsanna, Brendel, Konstantin Alexander, Brenner, Stefan, De Wever, Olivier, Dolznig, Helmut, Eichsteininger, Julia, Giessrigl, Benedikt, Holzner, Silvio, Huttary, Nicole, Jäger, Walter, Koperek, Oskar, Krenn, Liselotte, Krieger, Sigurd, Krupitza, Georg, Mader, Robert M, Marian, Brigitte, Milovanovic, Daniela, Nguyen, Chi Huu, Schachner, Helga, Schmidt, Wolfgang M, Senfter, Daniel, Stadler, Mira, Stadler, Serena   +22 more
core   +1 more source

Trends in 25 years of antihypertensive agent utilization in Croatia – an alert for scientific community and healthcare providers

British Journal of Clinical Pharmacology, EarlyView.
Aims Hypertension is a leading modifiable risk factor for cardiovascular mortality worldwide. This study aimed to evaluate 25‐year trends in antihypertensive agent (AHA) utilization in Croatia between 2000 and 2024. Methods We conducted a national, population‐based analysis using IMS and IQVIA pharmaceutical databases.
Andrej Belančić, Marta Kučan Štiglić, Ana Jelaković, Bojan Jelaković, Dinko Vitezić   +4 more
wiley   +1 more source

Prognostic Factors of Renal Involvement in Systemic Sclerosis [PDF]

, 2018
Background/Aims: Renal involvement is common in systemic sclerosis (SSc), including asymptomatic reduction of glomerular filtration rate (GFR), increased renal resistance indices, scleroderma renal crisis (SRC) and ANCA-associated vasculitis. The aim was
Barbano, Biagio, Cianci, Rosario, Gasperini, Maria Ludovica, Gigante, Antonietta, Muscaritoli, Maurizio, Rosato, Edoardo   +5 more
core   +2 more sources

Nifedipine for primary dysmenorrhoea

Cochrane Database of Systematic Reviews, 2017
Dysmenorrhoea (period pain) is a common condition with a substantial impact on the well-being and productivity of women. Primary dysmenorrhoea is defined as recurrent, cramping pelvic pain that occurs with periods, in the presence of a normal uterus, ovaries and fallopian tubes.
Rachel A Earl, Rosalie M Grivell
openaire   +3 more sources

Voclosporin‐induced gingival enlargement: A case report

Clinical Advances in Periodontics, EarlyView.
Abstract Background Drug‐influenced gingival enlargement (DIGE) is a recognized adverse effect of certain medications, particularly immunosuppressants like cyclosporin and tacrolimus. However, there have been no documented cases of DIGE associated with voclosporin, a newer calcineurin inhibitor used primarily to treat lupus nephritis.
Francesca Racca, Jessica M. Greco, Dimitris N. Tatakis   +2 more
wiley   +1 more source

Efficacy and safety of oral nifedipine with or without vaginal progesterone in the management of threatened preterm labor

International Journal of Reproductive BioMedicine, 2019
Background Preterm labor (PTL) is a serious emergency wherein robust management is imperative for achieving improved outcome. Objective To evaluate the efficacy and safety of nifedipine alone vs nifedipine with vaginal ...
Bushra Ashraf
doaj   +1 more source

A correlative model to predict in vivo AUC for nanosystem drug delivery with release rate-limited absorption [PDF]

, 2012
Purpose. Drug release from nanosystems at the sites of either absorption or effect biophase is a major determinant of its biological action. Thus, in vitro drug release is of paramount importance in gaining insight for the systems performance in vivo ...
Adibkia, Khosro, Barzegar-Jalali, Azim, Barzegar-Jalali, Mohammad, Mohammadi, Ghobad, Mohammadi, Kaivan, Nokhodchi, Ali, Valizadeh, Hadi   +6 more
core   +3 more sources

Endothelium‐Independent Relaxation of Alkaloid Boldine in Isolated Aortas From Normotensive and Hypertensive Rats: Participation of Ca2+ Channels

Chemistry &Biodiversity, EarlyView.
Involvement of Ca2+ channels in boldine‐induced vascular relaxation. ABSTRACT The regulation of vascular tone plays a fundamental role in blood pressure homeostasis and still represents a significant challenge in clinical practice. Boldine, a naturally occurring alkaloid from Peumus boldus, has emerged as a compound of interest due to its therapeutic ...
Martina Odebrecht Cavichiolo, Rita de Cássia Vilhena da Silva, Valdir Cechinel Filho, Priscila de Souza   +3 more
wiley   +1 more source

Nifedipine treatment reduces resting calcium concentration, oxidative and apoptotic gene expression, and improves muscle function in dystrophic mdx mice. [PDF]

PLoS ONE, 2013
Duchenne Muscular Dystrophy (DMD) is a recessive X-linked genetic disease, caused by mutations in the gene encoding dystrophin. DMD is characterized in humans and in mdx mice by a severe and progressive destruction of muscle fibers, inflammation ...
Francisco Altamirano, Denisse Valladares, Carlos Henríquez-Olguín, Mariana Casas, Jose R López, Paul D Allen, Enrique Jaimovich   +6 more
doaj   +1 more source