Effects of Nifedipine on Renal and Cardiovascular Responses to Neuropeptide Y in Anesthetized Rats
Molecules, 2021 Neuropeptide Y (NPY) acts via multiple receptor subtypes termed Y1, Y2 and Y5. While Y1 receptor-mediated effects, e.g., in the vasculature, are often sensitive to inhibitors of L-type Ca2+ channels such as nifedipine, little is known about the role of ...
Angela Bischoff +2 more
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Ca2+ transients are not required as signals for long-term neurite outgrowth from cultured sympathetic neurons [PDF]
, 1990 A method for clamping cytosolic free Ca2+ ([Ca2+]i) in cultures of rat sympathetic neurons at or below resting levels for several days was devised to determine whether Ca2+ signals are required for neurite outgrowth from neurons that depend on Nerve ...
Murrell, R D +3 more
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The contribution of ionic currents to changes in refractoriness of human atrial myocytes associated with chronic atrial fibrillation [PDF]
, 2001 <b>Objective:</b> To investigate changes in human atrial single cell functional electrophysiological properties associated with chronic atrial fibrillation (AF), and the contribution to these of accompanying ion current changes.
Kane, K.A., Rankin, A.C., Workman, A.J.
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Comparison of the Efficacy of Nifedipine and Hydralazine in Hypertensive Crisis in Pregnancy [PDF]
Acta Medica Iranica, 2011 Intravenous hydralazine is a commonly administered arteriolar vasodilator that is effective for hypertensive emergencies associated with pregnancy. Oral nifedipine is an alternative in management of these patients.
Yashar Youefzadeh-Fard +6 more
doaj +2 more sources
Metabolism of the dihydropyridine calcium channel blockers mebudipine and dibudipine by isolated rat hepatocytes [PDF]
The prototype 1,4-dihydropyridine (1,4-DHP) nifedipine, indicated for the management of hypertension and angina pectoris, has drawbacks of rapid onset of vasodilating action and a short half-life.
Baarnhielm +15 more
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Pulmonary vasoconstrictor action of KCNQ potassium channel blockers [PDF]
, 2006 KCNQ channels have been widely studied in the nervous system, heart and inner ear, where they have important physiological functions. Recent reports indicate that KCNQ channels may also be expressed in portal vein where they are suggested to influence ...
AM Evans +23 more
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Elucidation of molecular kinetic schemes from macroscopic traces using system identification [PDF]
, 2017 Overall cellular responses to biologically-relevant stimuli are mediated by networks of simpler lower-level processes. Although information about some of these processes can now be obtained by visualizing and recording events at the molecular level, this
Brezina, Vladimir +6 more
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Study of nifedipine solubility in physical mixtures and solid dispersions
Разработка и регистрация лекарственных средствIntroduction. Poor aqueous solubility significantly hinders the bioavailability of numerous orally administered drugs. Nifedipine, a widely-used cardiovascular agent, is categorized as practically insoluble according to pharmacopoeias, thus presenting a ...
N. J. Dahma +2 more
doaj +1 more source
Chronic myocardial infarction promotes atrial action potential alternans, afterdepolarisations and fibrillation [PDF]
, 2013 Aims: Atrial fibrillation (AF) is increased in patients with heart failure resulting from myocardial infarction (MI). We aimed to determine the effects of chronic ventricular MI in rabbits on the susceptibility to AF, and underlying atrial ...
Antony J. Workman +55 more
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PENGARUH PENGGUNAAN NIFEDIPIN PADA PENDERITA HIPERTENSI TERHADAP LAJU ALIRAN SALIVA DAN PEMBESARAN GINGIVA [PDF]
, 2015 Background : The prevalence of hypertension is increasing in society. Nifedipine as one of antihypertensive drugs from Calcium Channel Blocker is the type of drug that is often used . The impact on the oral cavity due to the use of nifedipine in patients
Danniswara, Fadia Ghaisani +1 more
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