Results 41 to 50 of about 37,594 (237)

Therapeutic role of nifedipine in threatened preterm labor: Current evidence and future perspectives

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Preterm birth occurs in approximately 10% of all pregnancies, and is not only the leading cause of neonatal mortality but also a major contributor to short‐ and long‐term morbidities due to immaturity. Preterm birth has also been linked to an increased risk of maternal cardiovascular and cerebrovascular diseases, making it a critical concern ...
Hikaru Imatake, Yoshitsugu Chigusa, Haruta Mogami, Satoshi Morita, Masaki Mandai   +4 more
wiley   +1 more source

Deterioration of preexisting myoclonus following nifedipine use in parkinsonian syndrome: A case report

eNeurologicalSci
L-type calcium channel antagonists are uncommon causes of myoclonus, and the underlying mechanism remains unclear. Here, we report a case of parkinsonian syndrome with deterioration of preexisting myoclonus after nifedipine use.
Gohei Yamada, Takanari Toyoda, Eiichi Katada, Noriyuki Matsukawa   +3 more
doaj   +1 more source

Prenatal exposure to antihypertensive medication: A systematic review of neurodevelopmental and educational outcomes

JCPP Advances, EarlyView.
This systematic review investigated the association of prenatal exposure to antihypertensive medication with longer‐term poor neurodevelopmental outcomes by evaluating the findings from existing literature. We undertook a systematic review of previous studies looking specifically at neurodevelopmental outcomes in children.
Shrifah Alkhalaf, Sarjit Singh, Jill P. Pell, Scott M. Nelson, Daniel F. Mackay, Michael Fleming   +5 more
wiley   +1 more source

The Management of Parkinson's Disease Before, during and after Pregnancy—an MDS Scientific Issues Committee Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Pregnancy after a Parkinson's diagnosis presents complex challenges. Due to the paucity of literature, there is no evidence‐based guidelines and protocols for preconception care, management of pregnancy, childbirth and the postpartum period in women with early‐onset Parkinson's disease (PD).
Alexander C. Lehn, Jee‐Young Lee, Giorgia Sciacca, Stacy Patterson, Adam Morton, Paul Pun, Walaa A. Kamel, Marina Picillo, Bart Post, Eng‐King Tan, Tamine Capato, Bastiaan R. Bloem, Manon Auffret, Annelien M. Oosterbaan, Willanka Kapelle, Michiko K. Bruno, Lorraine V. Kalia, Jeffrey H. Kordower, Daniela Berg   +18 more
wiley   +1 more source

The Antihypertensive Drug Nifedipine Modulates the Metabolism of Chondrocytes and Human Bone Marrow-Derived Mesenchymal Stem Cells

Frontiers in Endocrinology, 2019
Aging is associated with the development of various chronic diseases, in which both cardiovascular disorders and osteoarthritis are dominant. Currently, there is no effective treatment for osteoarthritis, whereas hypertension is often treated with L-type
Ilona Uzieliene, Eiva Bernotiene, Greta Rakauskiene, Jaroslav Denkovskij, Edvardas Bagdonas, Zygmunt Mackiewicz, Narunas Porvaneckas, Giedrius Kvederas, Ali Mobasheri, Ali Mobasheri, Ali Mobasheri, Ali Mobasheri   +11 more
doaj   +1 more source

Association between fetal brain diffusion‐weighted imaging and postnatal neurodevelopmental outcome after prenatal myelomeningocele repair

Ultrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective Myelomeningocele (MMC) is associated with significant alterations of the brain microstructure, which can impair long‐term neurodevelopmental outcomes. By measuring the random displacement of water molecules within the brain, magnetic resonance imaging (MRI)‐based diffusion‐weighted imaging (DWI) can provide objective metrics, such as
R. Corroenne, T. A. G. M. Huisman, W. E. Whitehead, A. A. Nassr, J. L. Munoz, J. Castillo, H. Castillo, R. M. Johnson, R. V. Donepudi, M. A. Belfort, M. Sanz‐Cortes   +10 more
wiley   +1 more source

The Effect of Topical Nifedipine in Treatment of Chronic Anal Fissure [PDF]

Acta Medica Iranica, 2010
Chronic anal fissure is the most common cause of anal pain associated with internal anal sphincter hypertonia. Reduction of hypertonocity is a special treatment for fissure healing.
Farzaneh Golfam, Parisa Golfam, Alireza Khalaj, Sayed Saaid Sayed Mortaz   +3 more
doaj   +1 more source

Effectiveness of 0.2% Glyceryl trinitrate and 0.5% Nifedipine in the Treatment of Chronic Anal Fissure

Journal of Nepal Medical Association, 2017
Introduction: Anal fissure is an ischemic ulcer caused by combination of spasm of internal anal sphincter and poor blood supply to the posterior midline of anal canal.
Suman Kumar Shrestha, Prabin Bikram Thapa, Dhiresh Kumar Maharjan, Tseten Yonjan Tamang   +3 more
doaj   +1 more source

Contribution of baicalin on the plasma protein binding displacement and CYP3A activity inhibition to the pharmacokinetic changes of nifedipine in rats in vivo and in vitro. [PDF]

PLoS ONE, 2014
Baicalin purified from the root of Radix scutellariae is widely used in clinical practices. This study aimed to evaluate the effect of baicalin on the pharmacokinetics of nifedipine, a CYP3A probe substrate, in rats in vivo and in vitro. In a randomised,
Zhen-Yu Cheng, Xin Tian, Jie Gao, Hong-Meng Li, Lin-Jing Jia, Hai-Ling Qiao   +5 more
doaj   +1 more source

Lycium barbarum polysaccharides enhance testicular spermatogenesis in d‐galactose‐induced aging rats via calcium signaling

Andrology, EarlyView.
Abstract Background Lycium barbarum polysaccharide (LBP) has long been recognized as having a wide range of beneficial properties for improving proliferation. However, the protective effects and specific mechanisms of d‐galactose‐induced testicular dysfunction in reproductively senescent rats are not fully understood.
Wenxin Ma, Chang Liu, Jing Pu, Ziyu Liu, Na Hu, Li Yang, Dongmei Chen, Hongmei Li, HuiMing Ma   +8 more
wiley   +1 more source