Results 41 to 50 of about 2,411,456 (284)
Image Analysis of Confocal Laser Scanning Microscope by the Macro Command with NIH Image [PDF]
, 2007 P(論文)Digital images of confocal laser scanning microscope were analyzed by using several macro commands with NIH Image software to reveal the influence of He-Ne laser irradiation on the cytoplasmic organelles in MC3T3-E1 osteogenic cells.
SAITO, Isamu +5 more
core
NIH-3T3 cells express FAP-tagged CXCR4 and US27 receptors.
, 2017 (A) NIH-3T3 mouse fibroblasts were stably transfected with plasmids encoding αFAP-tagged CXCR4 and βFAP-tagged US27. Cells were labeled with membrane impermeable α and β fluorogens, and surface expression of each receptor measured via flow cytometry. The
Juliet V. Spencer (521467) +1 more
core +1 more source
Frontiers in Pharmacology, 2016 Apolipoprotein A-I (apoA-I) and high-density lipoproteins (HDL) mediate reverse cholesterol transport out of cells. Furthermore, HDL has additional protective functions, which include anti-oxidative, anti-inflammatory, anti-apoptotic, and vasoprotective
Elizabeth M. Gordon +4 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Prevention of Irreversible Autoimmune Endocrinopathies in APECED with Ruxolitinib
Journal of Human ImmunityAutoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED/APS-1) is a monogenic disorder of failed central tolerance caused by deleterious variants in the autoimmune regulator (AIRE) gene. Interferon-γ-driven inflammation in APECED underlies
Joseph Pechacek +19 more
doaj +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Generalist Repository Ecosystem Initiative (GREI) Workshop
, 2023 The Generalist Repository Ecosystem Initiative (GREI) hosted a 2-day virtual workshop presented by the seven participating generalist repositories on January 24 & 25, 2023.
David Scherer +26 more
core +1 more source
Scientific Reports, 2022 DNA damage is a prominent biomarker for numerous diseases, including cancer, as well as for the aging process. Detection of DNA damage routinely relies on traditional microscopy or cytometric methods.
Kelsey Gallant +6 more
doaj +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source