Results 61 to 70 of about 2,430,619 (291)
A major advantage of immunotherapy of cancer is that effector cells induced at one site should be able to kill metastatic cancer cells in other sites or tissues.
Jessica J. O'Konek +7 more
doaj +1 more source
The National Institutes of Health (NIH) is the primary federal government agency for biomedical research in the USA. NIH provides extensive support for human microbiome research with 21 of 27 NIH Institutes and Centers (ICs) currently funding this area ...
NIH Human Microbiome Portfolio Analysis Team
core +1 more source
Visualizing the Nutritional Landscape of Food: An NIH Codeathon Project
Making nutrition and dietary choices are among the most critical aspects of daily life, and as such are subject to conflicting influences from research and media.
Thomas, Adam G +6 more
core +1 more source
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Exploiting Synergy: Immune-Based Combinations in the Treatment of Prostate Cancer
Cancer treatment is being revolutionized by the emergence of immunotherapies such as immune check point inhibitors and therapeutic cancer vaccines. Prostate cancer has is amenable to such therapeutic approaches.
Mauricio eBurotto +4 more
doaj +1 more source
Image Analysis of Confocal Laser Scanning Microscope by the Macro Command with NIH Image
P(論文)Digital images of confocal laser scanning microscope were analyzed by using several macro commands with NIH Image software to reveal the influence of He-Ne laser irradiation on the cytoplasmic organelles in MC3T3-E1 osteogenic cells.
SAITO, Isamu +5 more
core
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
P469: Clinical relevance of mosaic variants detected from exome sequencing data
Rajarshi Ghosh +7 more
doaj +1 more source

