Results 71 to 80 of about 2,411,456 (284)

The author addendum required for NIH employees

, 2008
The NIH has released the author addendum (or "cover sheet") it requires when NIH employees publish articles based on NIH-funded research. (Thanks to Michael A.
Peter Suber
core   +1 more source

O30: Graphics and filters make it easier to evaluate many variants in ClinVar search results*

Genetics in Medicine Open, 2023
Melissa Landrum, Shanmuga Chitipiralla, Kuljeet Kaur, Douglas Hoffman, Vitaly Lyoshin, Zenith Maddipatla, David Shao, Guangfeng Song, George Zhou, Andrew Russette, Brandi Kattman   +10 more
doaj   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

NiH-Catalyzed Proximal-Selective Hydroamination of Unactivated Alkenes with Anthranils

The regioselective hydroamination of unactivated alkenes is a long-standing challenge in organic synthesis. Herein, we report a NiH-catalyzed proximal-selective hydroamination of unactivated alkenes with 8-aminoquinoline (AQ) as a bidentate auxiliary and
Yinglin Luo (13944394), Wanxuan Zhao (13944391), Yushan Cui (10486672), Yanping Huo (545287), Xiao-Qiang Hu (1528684), Haiyi Xie (12258164), Yang Gao (18005)   +6 more
core   +1 more source

NIH public access working group

, 2005
The NIH has named the 17 members of the Public Access Working Group. The list is a mix of friends and foes of OA. If you recall, the public-access policy (Section II.F) sets up the working group in order to "advise NIH/NLM on implementation and assess ...
Peter Suber
core   +1 more source

Exploiting Synergy: Immune-Based Combinations in the Treatment of Prostate Cancer

Frontiers in Oncology, 2014
Cancer treatment is being revolutionized by the emergence of immunotherapies such as immune check point inhibitors and therapeutic cancer vaccines. Prostate cancer has is amenable to such therapeutic approaches.
Mauricio eBurotto, Nishith eSingh,, Christopher R Heery, James L. Gulley, Ravi Amrit Madan   +4 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Zerhouni supports NIH OA plan

, 2004
Paula Park, NIH research to be open access, <em> The Scientist </em> , July 29, 2004. Excerpt: "National Institutes of Health (NIH) director Elias Zerhouni indicated at a gathering of 43 scientific journal publishers and editors Wednesday ...
Peter Suber
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

NIH Toolbox Cognition User Guide [PDF]

The NIH Toolbox Cognition battery is a suite of digital cognitive assessment administered via iPad. Version 2 of the NIH Toolbox was used during Add Health Wave VI data collection period and was accessed via the NIH Toolbox application on a 9th ...
Stebbins, Rebecca C., Aiello, Allison E., Plassman, Brenda L., Parker, Cherese N.B., Hummer, Robert A., Bennett, David A., Rob, Farizah I., Manly, Jennifer J.   +7 more
core   +1 more source