Results 31 to 40 of about 6,305 (154)

Patterns of Drug and Polydrug Detection in Drivers Suspected of Driving Under the Influence of an Intoxicant in Ireland 2019–2020: A Latent Class Analysis

Drug and Alcohol Review, Volume 45, Issue 1, January 2026.
ABSTRACT Introduction Driving under the influence of drugs is a major risk factor for road traffic collisions. While increasing harms are observed in relation to polydrug use, evidence is needed about this issue in the context of road safety. We examined polydrug use patterns in drivers providing samples for toxicological analysis in Ireland between ...
Louise Durand, Aoife O'Kane, Richard Maguire, Denis Cusack, Eamon Keenan, Gráinne Cousins   +5 more
wiley   +1 more source

Counterfeit ‘Xanax®’ tablets: A comparative study of clinical and seizure data in Victoria, Australia

Addiction, Volume 120, Issue 12, Page 2465-2475, December 2025.
Abstract Background and aim There is growing evidence of counterfeit benzodiazepine products containing other substances, including non‐regulated benzodiazepine‐type new psychoactive substances (NPSs). This study sought to compare detections of seized suspect counterfeit alprazolam products with clinical cases that reported use of an alprazolam ...
Rebekka Syrjanen, Shaun L. Greene, Sarah E. Hodgson, Rachelle Abouchedid, Dimitri Gerostamoulos, Christie Magee, Melissa Bremner, Jennifer L. Schumann, on behalf of the Emerging Drugs Network of Australia – Victoria (EDNAV) research group   +8 more
wiley   +1 more source

Sedation for Gastrointestinal Endoscopic Procedures in the Elderly: Getting Safer but Still Not Nearly Safe Enough [PDF]

, 2006
Previously published UK reports showed that excessively large doses of benzodiazepines and opiates were being commonly used to sedate elderly patients for gastrointestinal (GI) endoscopy. This unsafe practice has lead to avoidable morbidity and mortality.
Bell, G. D., Bowles, J, De La Iglesia, Beatriz, Gray, A, Lord, David, Quine, A, Rayward-Smith, Vic, Reynolds, Alan, Romaya, C   +8 more
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Access of medication review for people living with dementia: An analysis of inequality using Swedish register data

Alzheimer's &Dementia, Volume 21, Issue 11, November 2025.
Abstract INTRODUCTION This study examines medication reviews (MRs) among people living with dementia (PWD) in Sweden, focusing on frequency and factors influencing access. METHODS Using nationwide register data, all diagnosed PWD from 2010 to 2016 were assessed for MR receipt in 2015 and/or 2016.
Sanjib Saha, Sofie Persson, Johan Jarl, Dominic Trepel, Cecilia Lenander, Elisabet Londos, Patrik Midlöv, Brian Lawlor, Håkan Toresson, UlfG Gerdtham   +9 more
wiley   +1 more source

Long‐Term Use of Benzodiazepines and Related Drugs in Persons With Major Depressive Disorder

Brain and Behavior, Volume 15, Issue 11, November 2025.
ABSTRACT Introduction Benzodiazepines and related drugs (BZDRs) may be prescribed to treat anxiety and insomnia in persons with depression. Although BZDRs are recommended for short‐term use only, their use may be prolonged. Despite research on the use of BZDRs in depression, to our knowledge, long‐term use and its predictors have not been previously ...
Heli Laitinen, Miia Tiihonen, Antti Tanskanen, Jari Tiihonen, Johannes Lieslehto, Marjaana Koponen, Heidi Taipale   +6 more
wiley   +1 more source

Flunitrazepam Excretion Patterns using the Abuscreen OnTrak and OnLine Immunoassays: Comparison with GC-MS [PDF]

, 2017
A study was conducted to compare the performance of the OnLine and OnTrak immunoassays for benzodiazepines with gas chromatographic-mass spectrometric (GC-MS) analysis in detecting flunitrazepam (FNP) and its metabolites in human urine.
Brenneisen, R., Brenneisen, R., Brenner, C., ElSohly, M.A., Feng, S., Goc-Szkutnicka, K., Honasoge, S., McNally, A.J., Passarelli, J., Salamone, S.J.   +9 more
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Photopharmacology beyond azobenzene photoswitches

Responsive Materials, Volume 3, Issue 4, November 2025.
Photopharmacology is advancing beyond traditional azobenzene photoswitches by developing new photoresponsive molecules with improved thermal stability, efficiency, and long‐wavelength activation, enhancing their potential for precise biomedical applications.
Huichao Guo, Jinghong Dai, Long Deng, Zhiwei Zhang, He Tian, Junji Zhang   +5 more
wiley   +1 more source

TREC-Rio trial: a randomised controlled trial for rapid tranquillisation for agitated patients in emergency psychiatric rooms [ISRCTN44153243] [PDF]

, 2002
Agitated or violent patients constitute 10% of all emergency psychiatric treatment. Management guidelines, the preferred treatment of clinicians and clinical practice all differ.
A Jablensky, B Thornley, CB Joy, Clive E Adams, E Coutinho, Evandro SF Coutinho, Expert Consensus Guideline Group, F Moritz, G Huf, Gisele Huf, HI Kaplan, J Ludbrook, JG Cunnane, LS Pilowsky, M Fenton, M Hotopf, M Wyant, P Armitage, RL Binder, The Royal College of Psychiatrists, VW Berger, Z Atakan   +21 more
core   +3 more sources

A model‐based cost‐effectiveness estimates of hormonal therapy in Indian children with infantile epileptic spasms syndrome

Epilepsia Open, Volume 10, Issue 5, Page 1404-1414, October 2025.
Abstract Objective Due to the conflicting evidence and expected regional therapeutic variations for cost‐effectiveness in children with infantile epileptic spasms syndrome (IESS), this study assessed treatment effectiveness, safety, Health‐Related Quality of Life (HRQoL), and performed a cost‐effectiveness analysis (CEA) for hormonal therapies in ...
Nagita Devi, Priyanka Madaan, Saroj Kundan Bharti, Jitendra Kumar Sahu, Dipika Bansal   +4 more
wiley   +1 more source

Current practices in managing acutely disturbed patients at three hospitals in Rio de Janeiro-Brazil: a prevalence study [PDF]

, 2002
The medical management of aggressive and violent behaviour is a critical situation for which there is little evidence. In order to prepare for a randomised trial, due to start in the psychiatric emergency rooms of Rio de Janeiro in 2001, a survey of ...
Adams, C.E., Carvalho, A, Coutinho, E, Fagundes, H.M., Gewandszajder, M, Huf, G, Keusen, A, Lopez, J, Oliveira, E.S.   +8 more
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