Results 1 to 10 of about 646,019 (403)
Therapeutic strategies to address neuronal nitric oxide synthase deficiency and the loss of nitric oxide bioavailability in Duchenne Muscular Dystrophy [PDF]
Orphanet Journal of Rare Diseases, 2017 Duchenne Muscular Dystrophy is a rare and fatal neuromuscular disease in which the absence of dystrophin from the muscle membrane induces a secondary loss of neuronal nitric oxide synthase and the muscles capacity for endogenous nitric oxide synthesis ...
Cara A. Timpani +2 more
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Tetrahydrobiopterin in nitric oxide synthase [PDF]
IUBMB Life, 2013 AbstractSummary: Nitric oxide synthase (NOS) is a critical enzyme for the production of the messenger molecule nitric oxide (NO) from L‐arginine. NOS enzymes require tetrahydrobiopterin as a cofactor for NO synthesis. Besides being one of the few enzymes to use this cofactor, the role of tetrahydrobiopterin in NOS catalytic mechanism is different from ...
J. Tejero, D. Stuehr
semanticscholar +3 more sources
Role of Asymmetric Dimethylarginine in Psychiatric Disorders [PDF]
Psikiyatride Güncel Yaklaşımlar, 2014 Asymmetric dimethylarginine has been a post-translational modified form of the aminoasid arginine. Being a competitive inhibitor of nitric oxide synthase enzyme, makes asymmetric dimethylarginine important.
Selma Bozkurt Zincir, Serkan Zincir
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Pulmonary Circulation, 2021 The L-arginine precursor, L-citrulline, re-couples endothelial nitric oxide synthase, increases nitric oxide production, and ameliorates chronic hypoxia-induced pulmonary hypertension in newborn pigs.
Matthew S. Douglass +3 more
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The Major Heat Shock Proteins, Hsp70 and Hsp90, in 2-Methoxyestradiol-Mediated Osteosarcoma Cell Death Model [PDF]
, 2020 2-Methoxyestradiol is one of the natural 17β-estradiol derivatives and a potential novel anticancer agent currently being under evaluation in advanced phases of clinical trials.
Cappello F. +8 more
core +1 more source
Inducible nitric oxide synthase: Regulation, structure, and inhibition
Medicinal research reviews (Print), 2020 A considerable number of human diseases have an inflammatory component, and a key mediator of immune activation and inflammation is inducible nitric oxide synthase (iNOS), which produces nitric oxide (NO) from l‐arginine.
Maris A. Cinelli +3 more
semanticscholar +1 more source
The Effect of Pneumonic Pasteurellosis on Apoptosis and Nitric Oxide Synthase in the Lungs in Calves
Turkish Journal of Agriculture: Food Science and Technology, 2020 Pneumonic Pasteurellosis (PP) is an infectious disease caused by Pasteurella multocida and Mannheimia haemolytica, mostly observed in cattle, sheep and calves. PP is characterized by fibrinous bronchopneumonia and pleuritis in the lungs.
Orhan Yavuz, Güngör Çağdaş Dinçel
doaj +1 more source
Turkish Journal of Hematology, 2011 OBJECTIVE: This study aimed to biochemically measure the production of nitric oxide in gingival crevicular fluid and immunohistochemically measure the expression of inducible nitric oxide synthase in the gingiva of patients with sickle cell disease ...
Esra Güzeldemir +4 more
doaj +3 more sources
Scientific African, 2021 Nitric oxide maintains the integrity of the gastric epithelium and is also elevated in diarrheal disease condition. Nitric oxide synthase isoforms (NOS) are responsible for production of nitric oxide (NO) in physiological and pathophysiological ...
Ebuka E. David +3 more
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Neural Regeneration Research, 2023 Dysfunction of neuronal nitric oxide synthase contributes to neurotoxicity, which triggers cell death in various neuropathological diseases, including epilepsy.
Xiao-Xue Xu +13 more
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