Results 101 to 110 of about 361,848 (377)
Mechanical Biomimetic Nanocomposites for Multidimensional Treatment of Arterial Thrombosis
Advanced Science, EarlyView.In this study, a mechanical biomimetic nanocomposite is developed, guided by photoacoustic imaging, to achieve highly efficient and safe thrombolysis through the synergistic effects of photothermal therapy and pharmacological intervention. Most notably, the nanoparticle improves the microenvironment of arterial thrombi, marked by high shear stress and ...
Ying Li +6 more
wiley +1 more source
Molecules, 2010 Two isomeric N-(methoxycarbonylthienylmethyl)thioureas were synthesised by a sequence of radical bromination of methylthiophenecarboxylic esters, substitution with trifluoroacetamide anion, deprotection, formation of the corresponding isothiocyanates and
Michael D. Threadgill +2 more
doaj +1 more source
Octacalcium phosphate crystals directly stimulate expression of inducible nitric oxide synthase through p38 and JNK mitogen-activated protein kinases in articular chondrocytes [PDF]
, 2005 Basic calcium phosphate (BCP) crystals, including hydroxyapatite, octacalcium phosphate (OCP) and carbonate-apatite, have been associated with severe osteoarthritis and several degenerative arthropathies.
Ea, Hang-Korng +3 more
core +6 more sources
Advanced Science, EarlyView.The elasticity of lipid nanoparticles (LNPs) is essential to their tumor‐targeting efficacy. Softer LNPs penetrate tumors faster and more easily enter into softer cancer cells, while stiffer LNPs show prolonged retention in stiffer tumors. The presence of protumoral M2 macrophages enhances the LNPs uptake into stiffer cancer cells, facilitating ...
Eunhee Lee +5 more
wiley +1 more source
Kidney & Blood Pressure Research, 2014 Background/Aims: To investigate the role of endothelial dysfunction on left ventricular remodeling in patients with chronic kidney disease and to evaluate the correlation between endothelial dysfunction and left ventricular remodeling.
Tao Peng +4 more
doaj +1 more source
Modelling the Role of Nitric Oxide in Cerebral Autoregulation [PDF]
arXiv, 2015 Malfunction of the system which regulates the bloodflow in the brain is a major cause of stroke and dementia, costing many lives and many billions of pounds each year in the UK alone. This regulatory system, known as cerebral autoregulation, has been the subject of much experimental and mathematical investigation yet our understanding of it is still ...
arxiv
The efficient photodesorption of nitric oxide (NO) ices A laboratory astrophysics study [PDF]
, 2017 The study and quantification of UV photon-induced desorption of frozen molecules furthers our understanding of the chemical evolution of cold interstellar regions. Nitric oxide (NO) is an important intermediate species in both gas-phase and solid-phase chemical networks.
arxiv +1 more source
Engineering an inducible NO pathway to facilitate cell-electronics communication [PDF]
, 2012 PhD ThesisTurning cells into useful devices to perform unnatural functions creates the potential to permit the interface between biological organisms and electronics.
Yarkoni, Orr
core
Postsynaptic α1-Adrenergic vasoconstriction is impaired in young patients with vasovagal syncope and is corrected by nitric oxide synthase inhibition [PDF]
, 2016 BACKGROUND: Syncope is a sudden transient loss of consciousness and postural tone with spontaneous recovery; the most common form is vasovagal syncope (VVS).
Medow, MS +6 more
core +1 more source
Advanced Science, EarlyView.Gut metabolite trimethylamine N‐oxide accumulates in the diabetic wound area to amplify macrophage inflammation via enhancing glycolysis activities. Kinsenoside induces macrophage repolarization from M1 to M2 phenotype through inhibiting IRE1α/XBP1 pathway, followed by HIF‐1α‐glycolysis axis repression and mitophagy‐oxidative phosphorylation axis ...
Li Lu +13 more
wiley +1 more source