Results 261 to 270 of about 361,848 (377)

Emerging approaches to investigating functional protein dynamics in modular redox enzymes: Nitric oxide synthase as a model system. [PDF]

J Biol Chem
Jiang T, Thielges MC, Feng C.
europepmc   +1 more source

Iguratimod alleviated Sjögren's syndrome through regulating macrophage polarization

Rheumatology &Autoimmunity, EarlyView.
Nonobese diabetic (NOD) mice exhibited characteristic of Sjögren's syndrome (SS), with increased M1 macrophages and deceased M2 macrophages. Iguratimod alleviated SS‐like symptoms and restored balance of macrophage polarization through inhibiting the mitogen‐activated protein kinases pathway in NOD mice.
Junqiao Guo, Yu Chen, Shumin Wang, Tingting Jiang, Yue Wang, Haolin Wu, Xiaojing Li, Genhong Yao   +7 more
wiley   +1 more source

Modulation of heme peroxo nucleophilicities with axial ligands reveal key insights into the mechanistic landscape of nitric oxide synthase. [PDF]

Chem Sci
Rajapakse S, Lee Y, Jayawardana SB, Helms J, Mondal P, Singh A, Pierce BS, Shafaat HS, Wijeratne GB.   +8 more
europepmc   +1 more source

Electron transfer in the nitric-oxide synthases. Characterization of L-arginine analogs that block heme iron reduction.

, 1994
Husam M. Abu‐Soud, Paul L. Feldman, Pamela Clark, Dennis J. Stuehr   +3 more
openalex   +1 more source

Absence of cerebellar long-term depression in mice lacking neuronal nitric oxide synthase. [PDF]

, 1997
Varda Lev‐Ram, Z Nebyelul, Mark H. Ellisman, Paul L. Huang, Roger Y. Tsien   +4 more
openalex   +1 more source

Formation of a β‐Endorphin Corona Mitigates Alzheimer's Amyloidogenesis

Small, EarlyView.
This study revealed the molecular mechanism of exercise‐induced β‐endorphin in suppressing the toxicity of Alzheimer's Aβ in vitro, in vivo and in silico. Abstract Senile plaques, comprised of nanosized aggregates of amyloid‐β (Aβ) peptides in the brain, are a pathological hallmark of Alzheimer's disease (AD).
Yunxiang Sun, Nicholas Andrikopoulos, Guofang Zhang, Yuying Liu, Xiufang Liang, Dongjie Li, Xiaoman Suo, Yue Wang, Yuhuan Li, Chuang Wang, Yang Li, Pu Chun Ke, Feng Ding   +12 more
wiley   +1 more source

Overcrowding Stress in Livestock Production Alters Gut Microbiota Composition and Neuronal Nitric Oxide Synthase (nNOS) Expression in nNOS-HiBiT Knock-in Mouse Model. [PDF]

Food Sci Anim Resour
Yeo S, Lee C, Park H, Eo K, Yeom SC, Kim H, Huh CS.   +6 more
europepmc   +1 more source

Multifunctional Bioactive Dual‐Layered Nanofibrous Matrix for Effective Breast Cancer Therapy and Enhanced Wound Healing

Small, EarlyView.
The multifunctional dual‐layered nanomatrix addresses post‐surgical challenges in triple‐negative breast cancer by integrating shape control, wound adherence, and tunable drug release. It delivers anticancer and antibacterial therapies through chemodynamic therapy, photothermal therapy, ferroptosis, cuproptosis, and sustained chemotherapy, enhancing ...
Sungyun Kim, Da In Jeong, Mrinmoy Karmakar, Ji‐Won Huh, Eun‐Hye Hong, Dae‐Joon Kim, Hyun‐Jeong Ko, Hyun‐Jong Cho, Ki‐Bum Lee   +8 more
wiley   +1 more source

Protein Tyrosine Phosphatase 1B (PTP1B) Deficiency Substantially Attenuates Glomerular Injury in Endothelial Nitric Oxide Synthase (eNOS)-Deficient Diabetic Mice. [PDF]

Cureus
Katagiri D, Nagasaka S, Takahashi K, Shimizu A, Harris RC, Takahashi T.   +5 more
europepmc   +1 more source

Nitric oxide synthase inhibition reduces caudate injury following transient focal ischemia in cats.

, 1994
T. Nishikawa, Jeffrey R. Kirsch, Raymond C. Koehler, Masayuki Miyabe, R. J. Traystman   +4 more
openalex   +1 more source