Nitric oxide synthases in mammals [PDF]
Nitric oxide is an inorganic free radical gas, of formula *N=O (abbreviated as NO). The discovery in 1987/88 that vascular endothelial cells are able to synthesize NO from L-arginine as a transcellular signal [1-4] was initially received by most biologists with considerable scepticism.
Salvador Moncada, Richard G. Knowles
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The aim of the study was to verify the hypothesis that intoxication with low doses of mycotoxins leads to changes in the mRNA expression levels of nitric oxide synthase-1 and nitric oxide synthase-2 genes in tissues of the gastrointestinal tract and the ...
Magdalena Gajęcka+4 more
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The effect of chronic peripheral nesfatin-1 application on blood pressure in normal and chronic restraint stressed rats: Related with circulating level of blood pressure regulators [PDF]
Nesfatin is a peptide secreted by peripheral tissues, central and peripheral nervous system. It is involved in the regulation of homeostasis. Although the effects of nesfatin-1 on nutrition have been studied widely in the literature, the mechanisms of ...
Ayada, C.+3 more
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Nitric Oxide Synthase Inhibitors as Antidepressants [PDF]
Affective and anxiety disorders are widely distributed disorders with severe social and economic effects. Evidence is emphatic that effective treatment helps to restore function and quality of life. Due to the action of most modern antidepressant drugs, serotonergic mechanisms have traditionally been suggested to play major roles in the pathophysiology
Wegener, Gregers, Volke, Vallo
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Role of Dietary Polyphenols in the Activity and Expression of Nitric Oxide Synthases: A Review
Nitric oxide (NO) plays several key roles in the functionality of an organism, and it is usually released in numerous organs and tissues. There are mainly three isoforms of the enzyme that produce NO starting from the metabolism of arginine, namely ...
Gabriele Serreli, Monica Deiana
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BACTERIAL NITRIC OXIDE SYNTHASE
The article provides the overview of modern scientific publications on the molecular structure, the mechanisms of synthesis of NO, molecular biology, genetics and biological function of bacterial nitric oxide synthase.
Б. М. Галкін+2 more
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Endothelial nitric oxide synthase activity involves in the protective effect of ascorbic acid against penicillin-induced epileptiform activity [PDF]
Ascorbic acid and nitric oxide are known to play important roles in epilepsy. The aim of present study was to identify the involvement of nitric oxide (NO) in the anticonvulsant effects of ascorbic acid on penicillin-induced epileptiform activity in rats.
Agar, Erdal+2 more
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Shear-Induced Nitric Oxide Production by Endothelial Cells [PDF]
We present a biochemical model of the wall shear stress (WSS)-induced activation of endothelial nitric oxide synthase (eNOS) in an endothelial cell (EC). The model includes three key mechanotransducers: mechanosensing ion channels, integrins and G-protein-coupled receptors. The reaction cascade consists of two interconnected parts.
arxiv +1 more source
Remarkably strong chemisorption of nitric oxide on insulating oxide films promoted by hybrid structure [PDF]
The remarkably strong chemical adsorption behaviors of nitric oxide on magnesia (001) film deposited on metal substrate have been investigated by employing periodic density functional calculations with Van der Waals corrections. The molybdenum supported magnesia (001) show significantly enhanced adsorption properties and the nitric oxide is chemisorbed
arxiv +1 more source
Exploring the Use of Inducible Nitric Oxide Synthase to Enhance Compost Nitrogen Content [PDF]
The goal of our research is to find and present new ways to introduce an inducible nitric oxide synthase to plants to better control nitrogen levels. We also looked at ways to introduce the synthase through compost.
Baker, Amelia
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