Results 71 to 80 of about 361,848 (377)

An Abnormal Nitric Oxide Metabolism Contributes to Brain Oxidative Stress in the Mouse Model for the Fragile X Syndrome, a Possible Role in Intellectual Disability [PDF]

open access: yes, 2015
Background. Fragile X syndrome is the most common genetic cause of mental disability. Although many research has been performed, the mechanism underlying the pathogenesis is unclear and needs further investigation.
Carolina Quintero-Navarro   +7 more
core   +3 more sources

Progress and Application of Multifunctional Hydrogel in Radioactive Skin Injury

open access: yesAdvanced Materials Interfaces, EarlyView.
This review examines healing challenges in radiation‐wound injuries, where ionizing radiation impairs immune and tissue repair processes. Hydrogels, with their biocompatibility, antimicrobial properties, and drug delivery capabilities, present a transformative solution. It compares hydrogel efficacy in radiation‐induced versus common wounds, highlights
Xinyue Cui   +5 more
wiley   +1 more source

Nanotherapy for Neural Retinal Regeneration

open access: yesAdvanced Science, EarlyView.
Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu   +11 more
wiley   +1 more source

Association between Polymorphism of Endothelial Nitric Oxide Synthase Gene (Glu298Asp) and Chronic Heart Failure in Patients with Ischemic Heart Disease and Obesity

open access: yesMìžnarodnij Endokrinologìčnij Žurnal, 2016
The article reviewed the links between polymorphism of endothelial nitric oxide synthase gene (Glu298Asp) and the development and progression of chronic heart failure in patients with ischemic heart disease and obesity.
O.I. Kadykova, P.P. Kravchun
doaj   +1 more source

β‐Glucuronidase‐Expressing Lactobacillus reuteri Triggers Irinotecan Enterotoxicity Through Depleting the Regenerative Epithelial Stem/Progenitor Pool

open access: yesAdvanced Science, EarlyView.
XLP mitigated CPT11 mucositis by suppressing GUS‐expressing microbes, notably L. reuteri, and diminishing bacterial GUS activity, consequently reducing SN38 accumulation to protect the intestinal epithelium. This preservation of the mucosal stem cell niche enabled rapid regeneration of secretory lineages such as mucin‐producing goblet cells, which ...
Bei Yue   +15 more
wiley   +1 more source

Evaluation of NO Synthase Activity in Meat-Brining Solutions: Implications for Meat Curing and Color Stability

open access: yesMolecules
L-arginine is a substrate for nitric oxide synthase, which, in its optimal conditions in a living organism, generates nitric oxide. In this presented research, we test the hypothesis that nitric oxide can be produced in a solution in which L-arginine ...
Marzena Zając, Rafał Szram
doaj   +1 more source

Nitric oxide mediates the stress response induced by diatom aldehydes in the sea urchin Paracentrotus lividus. [PDF]

open access: yesPLoS ONE, 2011
Diatoms are ubiquitous and abundant primary producers that have been traditionally considered as a beneficial food source for grazers and for the transfer of carbon through marine food webs.
Giovanna Romano   +4 more
doaj   +1 more source

The influence of nitric oxide on perigeniculate GABAergic cell activity in the anaesthetized cat [PDF]

open access: yes, 1996
[Abstract] We have tested the effect of iontophoretic application of the nitric oxide synthase inhibitor l-nitroarginine on the activity of a population of 53 perigeniculate (PGN) cells, recorded extracellularly in the anaesthetized paralysed cat. In all
Acuña, Carlos   +4 more
core   +2 more sources

Nitric Oxide/Nitric Oxide Synthase, Spermatogenesis, and Tight Junction Dynamics1 [PDF]

open access: yesBiology of Reproduction, 2004
During spermatogenesis, preleptotene and leptotene spermatocytes, residing in the basal compartment of the seminiferous epithelium, must traverse the blood-testis barrier (BTB) to gain entry to the adluminal compartment for further development at late stage VIII and early stage IX of the epithelial cycle.
Lee, NPY, Cheng, CY
openaire   +5 more sources

Tailoring a Functional Synthetic Microbial Community Alleviates Fusobacterium nucleatum‐infected Colorectal Cancer via Ecological Control

open access: yesAdvanced Science, EarlyView.
The bottom‐up strategy based on multiomics data is used for the SynCom design, and it successfully inhibited F. nucleatum growth and achieved stable colonization in vivo. In addition, it promoted tryptophan metabolism and secondary bile acid conversion, reduced lipid accumulation, relieved microbiome disorder, decreased inflammatory reaction, and ...
Zhongkun Zhou   +11 more
wiley   +1 more source

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