Results 111 to 120 of about 437,208 (310)
Modelling the Role of Nitric Oxide in Cerebral Autoregulation [PDF]
arXiv, 2015 Malfunction of the system which regulates the bloodflow in the brain is a major cause of stroke and dementia, costing many lives and many billions of pounds each year in the UK alone. This regulatory system, known as cerebral autoregulation, has been the subject of much experimental and mathematical investigation yet our understanding of it is still ...
arxiv
Animal Models and Experimental Medicine, EarlyView.Fuke Huahuang formulation (FHF) is used to treat vaginitis, and it exerts a promising anti‐inflammatory effect in clinical use. However, the detailed components and mechanisms of FHF for treating vaginitis remain unreported, and further preclinical evaluation is required to reveal its potential pharmacological activities against vaginitis.
Huiyu Liu +5 more
wiley +1 more source
PLoS ONE, 2019 Obesity-derived inflammation and metabolic dysfunction has been related to the activity of the inducible nitric oxide synthase (iNOS). To understand the interrelation between metabolism, obesity and NO., we evaluated the effects of obesity-induced NO ...
Pamela A Kakimoto +4 more
doaj +1 more source
International Journal of Mycobacteriology, 2014 Background: In earlier studies, it was shown that ex vivo Mycobacterium tuberculosis-infected type II alveolar epithelial cells generate de novo nitric oxide (NO), but the mycobactericidal quantity of NO was released only by stimulation of these cells ...
Sugata Roy +3 more
doaj +1 more source
Non‐NF‐κB elements are required for full induction of the rat type II nitric oxide synthase in vascular smooth muscle cells [PDF]
, 2000 Hanfang Zhang +3 more
openalex +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Amlodipine poisoning is a leading cause of cardiovascular medication‐related deaths, commonly managed with high‐dose insulin (HDI) therapy. However, HDI is a vasodilator that is counterproductive in managing vasoplegia. We aim to study HDI therapy in patients with hypotension following dihydropyridine calcium channel antagonist (CCA) overdose ...
Betty S. H. Chan +3 more
wiley +1 more source
Nanomaterials for enhanced X‐ray‐triggered cancer therapy: Progress and prospects
BMEMat, EarlyView.This review summarizes the latest progress in nanomaterials for X‐ray‐triggered cancer therapy, highlighting their various advantages such as targeted delivery, reduced side effects, and enhanced therapeutic efficacy. Abstract X‐rays, a form of ionizing radiation with high energy and significant penetration capability, are commonly used in clinical ...
Yuanchun Chen +6 more
wiley +1 more source
Synergistic induction of nitric oxide synthase type II: In vitro effect of leptin and interferon‐γ in human chondrocytes and ATDC5 chondrogenic cells [PDF]
, 2003 Miguel Otero +2 more
openalex +1 more source
BMEMat, EarlyView.The PCLA‐SNP scaffolds can produce photothermal agents in situ under ultraviolet radiation. Then, the scaffold can release nitric oxide gas spontaneously and generate hyperthermia under near‐infrared laser to enhance ablation of bone tumors. Furthermore, the calcium and iron ions released from PCLA‐SNP scaffolds can accelerate bone regeneration ...
Shaojie Dong +9 more
wiley +1 more source
Combating cancer immunotherapy resistance: a nano‐medicine perspective
Cancer Communications, EarlyView.Abstract Cancer immunotherapy offers renewed hope for treating this disease. However, cancer cells possess inherent mechanisms that enable them to circumvent each stage of the immune cycle, thereby evading anti‐cancer immunity and leading to resistance.
Xiangyi Kong +10 more
wiley +1 more source