Results 41 to 50 of about 159,122 (346)

Seasonal Variation of Glucosinolate Hydrolysis Products in Commercial White and Red Cabbages (Brassica oleracea var. capitata)

Foods, 2020
Brassica vegetables contain glucosinolates, which are well-known for their potential to form health-promoting isothiocyanates. Among those crucifers, white and red cabbage are commonly consumed vegetables, exhibiting different glucosinolate and ...
Nicole S. Wermter, Sascha Rohn, Franziska S. Hanschen   +2 more
doaj   +1 more source

Covalent Reversible Inhibitors of Cysteine Proteases Containing the Nitrile Warhead: Recent Advancement in the Field of Viral and Parasitic Diseases

Molecules, 2022
In the field of drug discovery, the nitrile group is well represented among drugs and biologically active compounds. It can form both non-covalent and covalent interactions with diverse biological targets, and it is amenable as an electrophilic warhead ...
Simone Brogi, Roberta Ibba, Sara Rossi, Stefania Butini, Vincenzo Calderone, Sandra Gemma, Giuseppe Campiani   +6 more
doaj   +1 more source

Functional Expression and Characterization of a Panel of Cobalt and Iron-Dependent Nitrile Hydratases

Molecules, 2020
Nitrile hydratases (NHase) catalyze the hydration of nitriles to the corresponding amides. We report on the heterologous expression of various nitrile hydratases.
Birgit Grill, Maximilian Glänzer, Helmut Schwab, Kerstin Steiner, Daniel Pienaar, Dean Brady, Kai Donsbach, Margit Winkler   +7 more
doaj   +1 more source

Direct Regioselective C-H Cyanation of Purines

Molecules, 2023
A direct regioselective C-H cyanation of purines was developed through a sequential triflic anhydride activation, nucleophilic cyanation with TMSCN, followed by a process of base-mediated elimination of triflous acid (CF3SO2H).
Luyong Li, Jie Hu, Yuqing Fu, Xiaolin Shi, Hongguang Du, Jiaxi Xu, Ning Chen   +6 more
doaj   +1 more source

Determination of Phenethyl Isothiocyanate, Erucin, Iberverin, and Erucin Nitrile Concentrations in Healthy and Pieris rapae-Infected Broccoli Tissues Using Gas Chromatography-Mass Spectrometry

Chemosensors
Cruciferous vegetables (Brassicaceae family) are a rich source of phytochemicals, in particular glucosinolates (GLS) and their hydrolysis products, isothiocyanates and nitriles.
Irene-Dimitra Mesimeri, Panagiota-Kyriaki Revelou, Violetta Constantinou-Kokotou, Maroula G. Kokotou   +3 more
doaj   +1 more source

Swelling Properties of Nitrile-butadiene Rubber with Different Acrylonitrile Content in Isopropyl Nitrate

Chemical Engineering Transactions, 2017
Nitrile-butadiene rubber is the sealing material of isopropyl nitrate; however, leakage or vaporization phenomena frequently occur. In order to analyze the causes of leakage and volatilization and study on the various properties of nitrile-butadiene ...
Lili Wu, Yukui Ding, Jianwei Zhen, Qian Zhang, Siyang Chen   +4 more
doaj   +1 more source

Kinetic, Spectroscopic, and X-Ray Crystallographic Evidence for the Cooperative Mechanism of the Hydration of Nitriles Catalyzed by a Tetranuclear Ruthenium-μ-oxo-μ-hydroxo Complex [PDF]

, 2008
The tetranuclear ruthenium-oxo-hydroxo-hydride complex {[(PCy3)(CO)RuH]4(μ4-O)(μ3-OH)(μ2-OH)} (1) was found to be a highly cooperative catalyst for the nitrile hydration reaction. The cooperative mechanism of the hydration of benzonitrile was established
Lindeman, Sergey V., Yi, Chae S., Zeczycki, Tonya N.   +2 more
core   +1 more source

Micellar electrokinetic capillary chromatography—Synchronous monitoring of substrate and products in the myrosinase catalysed hydrolysis of glucosinolates [PDF]

, 2006
A micellar electrokinetic capillary chromatography (MECC) method has been developed for monitoring the myrosinase catalysed hydrolysis of 2-hydroxy substituted glucosinolates and the simultaneous formation of the corresponding degradation products ...
Bellostas, Natalia, Sorensen, Hilmer, Sorensen, Jens Christian   +2 more
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

A simple, efficient and rapid screening technique for differentiating nitrile hydratase and nitrilase producing bacteria

Biotechnology Reports, 2019
Nitrile hydrolyzing enzymes catalyze the hydration of nitrile compounds to corresponding amides and acids. Bacteria, isolated from soil samples were screened for nitrile hydrolyzing enzymes by simple dye based 96 well plate and nesslerization method ...
Ruchi Sahu, Anil Kumar Meghavarnam, Savitha Janakiraman   +2 more
doaj   +1 more source