Results 91 to 100 of about 984,485 (282)

Selective nitrile oxide dipolar cycloaddition for the synthesis of highly functionalized β-aminocyclohexanecarboxylate stereoisomers

, 2012
Highly functionalized b-aminocyclohexanecarboxylate regio- and stereoisomers were synthesized from a bicyclic b-lactam by successive regioselective iodolactonization, stereo- and regioselective nitrile oxide cycloaddition, lactone ring-opening and ...
Fülöp Ferenc, Nonn Melinda, Kiss Loránd, Sillanpää Reijo, Kiss, Loránd, Nonn, Melinda, Sillanpää, Reijo, Fülöp, Ferenc   +7 more
core   +1 more source

H4K12 Lactylation Regulates NDUFS7 to Drive Microglia Reverse Electron Transport in Spinal Cord Injury

Advanced Science, EarlyView.
Lactate accumulation after SCI promotes H4K12la lactylation, which upregulates NDUFS7, triggering mitochondrial RET and ROS, enforcing pro‐inflammatory microglial polarization. MM@mPTC, a biomimetic nanotherapeutic, degrades LDHA in activated microglia, reducing H4K12la lactylation and blocking RET, thus curbing ROS, fostering a reparative phenotype ...
Chenglong Hong, Zhichen Jiang, Zhouwei Wu, Chenyu Wu, Jiang Liu, Kaijie Guo, Yihui Liang, Shaobo Xu, Yuchen Jin, Yong Xiao, Lei Guo, Hui Xu, Sunren Sheng, Chenggui Wang   +13 more
wiley   +1 more source

Chiral Lewis Acid Catalysis in Nitrile Oxide Cycloadditions

, 2016
We describe examples of highly regio- and enantioselective nitrile oxide cycloadditions to unsaturated alkenes using substoichiometric amounts of a chiral Lewis acid.
Mukund P. Sibi (1633159), Kennosuke Itoh (1574884), Craig P. Jasperse (1633156)   +2 more
core   +1 more source

PLOD1 Catalytic Activity Stabilizes ENO1 by Limiting FBXW7‐dependent Degradation to Promote Glycolysis and TMZ Resistance in Glioblastoma

Advanced Science, EarlyView.
PLOD1 interacts with ENO1 and limits its FBXW7‐dependent ubiquitination and proteasomal degradation through a mechanism requiring PLOD1 catalytic activity. ENO1 stabilization sustains glycolysis, promoting glioblastoma cell proliferation, migration, and temozolomide resistance.
Fen Xue, Dingkong Liang, Xin Chen, Fei Fan, Xiayun He   +4 more
wiley   +1 more source

Study on Nitrile Oxide for Low-Temperature Curing of Liquid Polybutadiene. [PDF]

Materials (Basel), 2022
Li P, Wang X.
europepmc   +1 more source

Protonation Modification of Commercial OPBI as Binders Toward High‐Performance High‐Temperature PEM Fuel Cells

Advanced Science, EarlyView.
Commercial OPBI binders is regulated via a facile formic‐acid protonation strategy without disrupting the polymer backbone. Protonation introduces positively charged benzimidazole sites, inducing interchain electrostatic repulsion that loosens chain packing, enlarges intermolecular spacing, and promotes uniform binder dispersion over catalyst surfaces.
Jinzhen Huang, Minhui Liang, Jingjing Lin, Zhihuan Pan, Jinwu Peng, Lei Wang   +5 more
wiley   +1 more source

Effect of Graphene Oxide on Anti-aging Property of Nitrile Butadiene Rubber

Cailiao gongcheng, 2017
The blends with higher damping performance was prepared based on nitrile butadiene rubber(NBR) with addition of graphene oxide(GO) and modified graphene oxide(MGO) prepared by improved Hammer method.
ZHANG Lin, CHEN Duo-li, ZHU Min-hao, CAI Zhen-bing, PENG Jin-fang   +4 more
doaj   +1 more source

Revealing Temperature‐Driven Interfacial Reactions of Succinonitrile in PEO‒LiTFSI Electrolytes and Suppressing Them via Dual PEDOT‐Based Interfacial Layers

Advanced Science, EarlyView.
Temperature‐driven interfacial reactions of succinonitrile in PEO‐LiTFSI electrolyte are revealed at both lithium and cathode interfaces, identifying cathode degradation as the dominant failure pathway. Dual PEDOT‐based interfacial protection suppresses these reactions, stabilizes both electrode interfaces, and enables durable wide‐temperature solid ...
Baskar Selvaraj, Hailemichael Ayalew, Yu‐Yao Tsai, Ly Tho Xuan, Jia‐Wei She, Hao‐Wen Liu, Ming‐Chou Chen, Yu‐Sheng Hsiao, Nae‐Lih Wu, Hsiao‐hua Yu   +9 more
wiley   +1 more source

Oral Actinomyces Species Exposure is Associated with Anxiety‐Like Behavior, Mitochondrial Remodeling, and Altered GABAergic Pathways

Advanced Science, EarlyView.
Oral exposure to cannabis‐associated Actinomyces species, particularly A. meyeri, is associated with anxiety‐like behavior in mice in the absence of detectable bacterial translocation or overt systemic inflammation. These findings support a potential oral‐brain metabolic axis involving candidate metabolites such as arginine and argininosuccinate ...
Tabinda Salman, Zhenwu Luo, Douglas Johnson, Arshad A. Noorani, Zhuang Wan, Bogdan Bordieanu, Zhi‐wei Ye, Rachel D. Penrod, Hongxu Xian, Sylvia Fitting, Peter W. Kalivas, Wei Jiang   +11 more
wiley   +1 more source

Novel silicon-bridged macrocycles: efficient synthesis by quadruple cycloadditive macrocyclization and intramolecular nitrile oxide dimerization

, 2000
Novel silacyclophanes have been synthesized by using quadruple cycloadditive macrocyclization and intramolecular nitrile oxide dimerization. The macrocyclic cycloadducts were characterized by spectroscopic methods and X-ray crystallography.
Hwang, GT, Lee, CW, Kim, BH, Byeang Hyean Kim, Chan Woo Lee, Gil Tae Hwang   +5 more
core   +1 more source