Results 171 to 180 of about 252,458 (275)
Clock Genes Regulate Ca2+ Signaling and Mitochondrial Bioenergetics to Inhibit Sjögren Disease
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjögren disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA sequencing, and mitochondrial activity were used to investigate the effects of
Viktor R. Drel +12 more
wiley +1 more source
A microelectrochemical analytical tool is proposed for the accelerated evaluation of the intrinsic electrochemical performance of Prussian‐blue analogues as solid active materials in Na+‐based batteries. By confining the solid active material inside a recessed microelectrode, accelerated voltammetric and galvanostatic cycling at high C‐rate become ...
Nomnotho Jiyane +9 more
wiley +1 more source
Regioselective approach to 5-arylsulfonylisoxazoles and their antimicrobial activity. [PDF]
Sazonov AS +9 more
europepmc +1 more source
Abstract Astaxanthin is a carotenoid with strong antioxidant properties, used in research on cancer treatment, ocular injuries, and neurological disorders. When produced by the microalgae Haematococcus lacustris, its antioxidant potential is even higher than that of the synthetic molecule, making it particularly attractive for pharmaceutical and ...
Renata Kühl Rocha +5 more
wiley +1 more source
Highly Stereoselective (3+2) Cycloadditions of Levoglucosenone (LGO) with the In Situ-Generated Thiocarbonyl <i>S</i>-Methanides (Thiocarbonyl Ylides) Derived from Aromatic and Cycloaliphatic Thioketones. [PDF]
Mlostoń G +4 more
europepmc +1 more source
ABSTRACT The biocatalytic production of nicotinic acid using nitrilases has emerged as a promising alternative to conventional chemical synthesis, offering improved selectivity and environmental sustainability. In this study, we developed a continuous‐flow millireactor system employing Escherichia coli cells expressing a nitrilase from Paraburkholderia
Jonathan Bassut +8 more
wiley +1 more source
Unexpected Synthesis of a Furoxan Derivative from 3-Acetyl-2,4,6-Trimethylpyridine: Structural Characterization and Biological Evaluation. [PDF]
Rakhimzhanova AS +7 more
europepmc +1 more source
Abstract DNA‐encoded libraries (DELs) enable large‐scale screening for hit identification, but accessing sp3‐rich, three‐dimensional chemotypes beyond flat, aromatic scaffolds remains challenging. Multicomponent reactions (MCRs) assemble such complexity from simple building blocks in a single step, and reaction‐engineering strategies have extended on ...
Jimin Moon +3 more
wiley +1 more source
P-Doped V-Cr composite oxide catalysts for the ammoxidation of 2,6-dichlorotoluene. [PDF]
Tang W +6 more
europepmc +1 more source
This review highlights critical “translational gaps” in understanding micro‐ and nanoplastics impacts on gastrointestinal diseases, bridging exposure, detecting, and mechanistic toxicology. Abstract Micro‐ and nanoplastics (MNPs) have become pervasive environmental contaminants with increasing evidence linking them to adverse health outcomes.
Zhenli Diao +3 more
wiley +1 more source

