Fe(III)/Pyridine N-oxide LMCT Photocatalysis for Unactivated C(sp<sup>3</sup>)-H Functionalizations. [PDF]
Luo J +5 more
europepmc +1 more source
Synthesis of benzisoxazoles by the [3 + 2] cycloaddition of in situ generated nitrile oxides and arynes. [PDF]
Dubrovskiy AV, Larock RC.
europepmc +1 more source
Pharmaceuticals Made with Hydrogen: A Sustainable and Efficient Approach Using Flow Synthesis
We demonstrate a sustainable strategy for pharmaceutical manufacturing by combining hydrogen, heterogeneous catalysis, and continuous flow synthesis. The development of novel catalysts and their application in a multi‐step synthesis of donepezil enabled a highly productive process with no intermediate purification.
Shū Kobayashi, Haruro Ishitani
wiley +1 more source
Recent Advances in Metal-Based Catalysts for Nitrile Hydration to Amides: Mechanistic Aspects. [PDF]
Essebbar FE +3 more
europepmc +1 more source
The Reactions of Nitrile N-Oxides
openaire +2 more sources
ABSTRACT Fluorouracil‐platinum(IV) prodrugs represent a novel class of multimechanistic chemotherapeutics with enhanced anticancer potential. The prodrugs PtIVP‐5FUMeOBut and PtIV56‐5FUMeOBut were actualized by derivatising the clinical drug 5‐fluorouracil (5FU) and coordinating it to platinum(IV) complexes, leveraging the established cytotoxicity of ...
Maria George Elias +9 more
wiley +1 more source
Synthesis of mono- and di-(<i>C</i>-glycopyranosyl-isoxazol(in)yl) derivatives on aromatic scaffolds and their evaluation as anti-adherence agents of <i>Candida albicans</i>. [PDF]
Kaszás T +9 more
europepmc +1 more source
Synthetic Strategies for Activity‐Based Probes to Decode Ubiquitin‐Like Modifiers
ABSTRACT Ubiquitin‐like proteins (Ubls) such as SUMO, NEDD8, ISG15, URM1, UFM1, FAT10, ATG8/ATG12, and FUBI are essential regulators of cellular homeostasis, controlling processes from protein stability and trafficking to immune signaling and autophagy.
Saibal Chanda +5 more
wiley +1 more source
Oil- and Fuel-Resistant Rubber for Pressure Hoses Containing Carbon-Based Technological Waste as a Filler. [PDF]
Nakyp A +6 more
europepmc +1 more source
Monosubstituted N‐arylhydroxylamines represent a unique subclass of hydroxylamines that act as pivotal intermediates in redox transformations and as versatile platforms for further synthetic transformations. They serve as key building blocks in the synthesis of architecturally complex heterocycles and other valuable organic compounds.
Michael G. Kallitsakis +2 more
wiley +1 more source

