Results 11 to 20 of about 6,046 (231)

Nature of the copper-nitrosyl intermediates of copper nitrite reductases during catalysis. [PDF]

Chem Sci, 2020
Observation of side-on copper-nitrosyl intermediate and its confirmation by DFT during catalysis of copper nitrite reductases.
Hough MA, Conradie J, Strange RW, Antonyuk SV, Eady RR, Ghosh A, Hasnain SS.   +6 more
europepmc   +2 more sources

Solution-State Inter-Copper Distribution of Redox Partner-Linked Copper Nitrite Reductases: A Pulsed Electron-Electron Double Resonance Spectroscopy Study. [PDF]

J Phys Chem Lett, 2022
Copper nitrite reductases (CuNiRs) catalyze the reduction of nitrite to form nitric oxide. In recent years, new classes of redox partner linked CuNiRs have been isolated and characterized by crystallographic techniques. Solution-state biophysical studies
Hedison TM, Iorgu AI, Calabrese D, Heyes DJ, Shanmugam M, Scrutton NS.   +5 more
europepmc   +3 more sources

A Novel Nitrite Reductase from Acinetobacter haemolyticus for Efficient Degradation of Nitrite

Biomolecules
Nitrite reductases play a crucial role in the nitrogen cycle, demonstrating significant potential for applications in the food industry and environmental remediation, particularly for nitrite degradation and detection.
Xiao-Yan Yin, Emmanuel Mintah Bonku, Jian-Feng Yuan, Zhong-Hua Yang   +3 more
doaj   +2 more sources

Single crystal spectroscopy and multiple structures from one crystal (MSOX) define catalysis in copper nitrite reductases. [PDF]

Proc Natl Acad Sci U S A, 2022
Many enzymes utilize redox-coupled centers for performing catalysis where these centers are used to control and regulate the transfer of electrons required for catalysis, whose untimely delivery can lead to a state incapable of binding the substrate, i.e.
Rose SL, Baba S, Okumura H, Antonyuk SV, Sasaki D, Hedison TM, Shanmugam M, Heyes DJ, Scrutton NS, Kumasaka T, Tosha T, Eady RR, Yamamoto M, Hasnain SS.   +13 more
europepmc   +2 more sources

SERR Spectroelectrochemical Study of Cytochrome cd1 Nitrite Reductase Co-Immobilized with Physiological Redox Partner Cytochrome c552 on Biocompatible Metal Electrodes. [PDF]

PLoS ONE, 2015
Cytochrome cd1 nitrite reductases (cd1NiRs) catalyze the one-electron reduction of nitrite to nitric oxide. Due to their catalytic reaction, cd1NiRs are regarded as promising components for biosensing, bioremediation and biotechnological applications ...
Célia M Silveira, Pedro O Quintas, Isabel Moura, José J G Moura, Peter Hildebrandt, M Gabriela Almeida, Smilja Todorovic   +6 more
doaj   +2 more sources

Phylogenetics and environmental distribution of nitric oxide-forming nitrite reductases reveal their distinct functional and ecological roles. [PDF]

ISME Commun
The two evolutionarily unrelated nitric oxide-producing nitrite reductases, NirK and NirS, are best known for their redundant role in denitrification. They are also often found in organisms that do not perform denitrification.
Pold G, Bonilla-Rosso G, Saghaï A, Strous M, Jones CM, Hallin S.   +5 more
europepmc   +3 more sources

Nitrite improved nitrification efficiency and enriched ammonia-oxidizing archaea and bacteria in the simultaneous nitrification and denitrification process

Water Research X, 2023
Simultaneous nitrification and denitrification (SND) is effective and energy-saving for wastewater treatment. As an inevitable intermediate product in the SND process, nitrite affects the efficiency of ammonia oxidation and the composition of nitrifiers.
Yu Xiang, Tengzhi Zhou, Siping Deng, Zhiyu Shao, Yiwen Liu, Qiang He, Hongxiang Chai   +6 more
doaj   +1 more source

The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression

Hepatology, EarlyView., 2022
Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro, Rut Espinosa‐Sotelo, Eva Crosas‐Molist, Macarena Herranz‐Itúrbide, Daniel Caballero‐Díaz, Ania Alay, Xavier Solé, Emilio Ramos, Teresa Serrano, María L. Martínez‐Chantar, Ulla G. Knaus, José M. Cuezva, Antonio Zorzano, Esther Bertran, Isabel Fabregat   +14 more
wiley   +1 more source

An investigation into the unusual linkage isomerization and nitrite reduction activity of a novel tris(2-pyridyl) copper complex [PDF]

Royal Society Open Science, 2017
The copper-containing nitrite reductases (CuNIRs) are a class of enzymes that mediate the reduction of nitrite to nitric oxide in biological systems. Metal–ligand complexes that reproduce the salient features of the active site of CuNIRs are therefore of
Isolda Roger, Claire Wilson, Hans M. Senn, Stephen Sproules, Mark D. Symes   +4 more
doaj   +1 more source

Structure and mechanism of copper–carbonic anhydrase II: a nitrite reductase

IUCrJ, 2020
Nitric oxide (NO) promotes vasodilation through the activation of guanylate cyclase, resulting in the relaxation of the smooth muscle vasculature and a subsequent decrease in blood pressure.
Jacob T. Andring, Chae Un Kim, Robert McKenna   +2 more
doaj   +1 more source