Impact of mitochondria on nitrite metabolism in HL-1 cardiomyocytes
Apart from ATP synthesis mitochondria have many other functions, one being nitrite reductase activity. NO released from nitrite has been shown to protect the heart from ischemia/reperfusion injury in a cGMP-dependent manner.
Peter eDungel+5 more
doaj +1 more source
Summary Our mini-review focuses on dual regulation of cellular nitric oxide (NO) signaling pathways by traditionally characterized enzymatic formation from L-arginine via the actions of NO synthases (NOS) and by enzymatic reduction of available cellular ...
G. Stefano, R. Kream
semanticscholar +1 more source
Biochemical properties of Paracoccus denitrificans FnrP:Reactions with molecular oxygen and nitric oxide [PDF]
In Paracoccus denitrificans, three CRP/FNR family regulatory proteins, NarR, NnrR and FnrP, control the switch between aerobic and anaerobic (denitrification) respiration.
A Volbeda+57 more
core +1 more source
Migraines Are Correlated with Higher Levels of Nitrate-, Nitrite-, and Nitric Oxide-Reducing Oral Microbes in the American Gut Project Cohort. [PDF]
Nitrates, such as cardiac therapeutics and food additives, are common headache triggers, with nitric oxide playing an important role. Facultative anaerobic bacteria in the oral cavity may contribute migraine-triggering levels of nitric oxide through the ...
Antonio Gonzalez+6 more
core +2 more sources
Bioaugmentation of UASB reactors with immobilized Sulfurospirillum barnesii for simultaneous selenate and nitrate removal [PDF]
Whole-cell immobilization of selenate-respiring Sulfurospirillum barnesii in polyacrylamide gels was investigated to allow the treatment of selenate contaminated (790¿µg Se¿×¿L-1) synthetic wastewater with a high molar excess of nitrate (1,500 times) and
Aelst, A.C., van+4 more
core +2 more sources
An integrated biochemical system for nitrate assimilation and nitric oxide detoxification in Bradyrhizobium japonicum [PDF]
Rhizobia are recognized to establish N(2)-fixing symbiotic interactions with legume plants. Bradyrhizobium japonicum, the symbiont of soybeans, can denitrify and grow under free-living conditions with nitrate (NO(3)(−)) or nitrite (NO(2)(−)) as sole ...
Alderton+69 more
core +1 more source
Characterization of denitrifying activity by the alphaproteobacterium, Sphingomonas wittichii RW1
Sphingomonas wittichii RW1 has no reported denitrifying activity yet encodes nitrite and nitric oxide reductases. The aims of this study were to determine conditions under which S.
Lisa Y Stein, Lynnie S Cua
doaj +1 more source
The NAD(P)H:flavin oxidoreductase from Escherichia coli. Evidence for a new mode of binding for reduced pyridine nucleotides [PDF]
The NAD(P)H:flavin oxidoreductase from Escherichia coli, named Fre, is a monomer of 26.2 kDa that catalyzes the reduction of free flavins using NADPH or NADH as electron donor. The enzyme does not contain any prosthetic group but accommodates both the reduced pyridine nucleotide and the flavin in a ternary complex prior to oxidoreduction.
arxiv +1 more source
Nitrous oxide production in soil isolates of nitrate-ammonifying bacteria [PDF]
Here we provide the first demonstration of the potential for N2O production by soil-isolated nitrate-ammonifying bacteria under different C and N availabilities, building on characterizations informed from model strains.
Bamford+29 more
core +2 more sources
The oral microbiome has the potential to provide an important symbiotic function in human blood pressure physiology by contributing to the generation of nitric oxide (NO), an essential cardiovascular signaling molecule.
Gena D. Tribble+16 more
doaj +1 more source