Results 71 to 80 of about 6,046 (231)

Comparative EPR studies on the nitrite reductases from Escherichia coli and Wolinella succinogenes

, 1987
Hexaheme nitrite reductases purified to homogeneity from Escherichia coli K-12 and Wolinella succinogenes were studied by low-temperature EPR spectroscopy.
M.-Y. Liu, Liu, M.-C., Payne, W.J., J. Le Gall, Le Gall, J., H.D. Peck, Peck, H.D., Liu, M.-Y., W.J. Payne, DerVartanian, D.V., M.-C. Liu, D.V. DerVartanian   +11 more
core   +1 more source

Predictive Biomarkers in Metastatic Colorectal Cancer Patients Treated With Bevacizumab: A Turkish Oncology Group (TOG) Study

International Journal of Cancer, EarlyView.
Bevacizumab added to systemic chemotherapy remains a cornerstone of metastatic colorectal cancer treatment, but its effectiveness is variable. Tumors can bypass the VEGF blockade by activating other pro‐angiogenic pathways, hampering the identification of predictive biomarkers.
Büsra Akay Hacan, Fatma Gizem Sonugür, Müge Öçal, Cansu Babahan, Samira Abgarmi, Ülkü Yalçıntaş Arslan, Mehmet Ali Şendur, Ahmet Demirkazık, Güngör Utkan, Hakan Akbulut   +9 more
wiley   +1 more source

Active-site protein dynamics and solvent accessibility in native Achromobacter cycloclastes copper nitrite reductase

IUCrJ, 2017
Microbial nitrite reductases are denitrifying enzymes that are a major component of the global nitrogen cycle. Multiple structures measured from one crystal (MSOX data) of copper nitrite reductase at 240 K, together with molecular-dynamics simulations ...
Kakali Sen, Sam Horrell, Demet Kekilli, Chin W. Yong, Thomas W. Keal, Hakan Atakisi, David W. Moreau, Robert E. Thorne, Michael A. Hough, Richard W. Strange   +9 more
doaj   +1 more source

Structures of substrate- and product-bound forms of a multi-domain copper nitrite reductase shed light on the role of domain tethering in protein complexes

IUCrJ, 2020
Copper-containing nitrite reductases (CuNiRs) are found in all three kingdoms of life and play a major role in the denitrification branch of the global nitrogen cycle where nitrate is used in place of dioxygen as an electron acceptor in respiratory ...
Daisuke Sasaki, Tatiana F. Watanabe, Robert R. Eady, Richard C. Garratt, Svetlana V. Antonyuk, S. Samar Hasnain   +5 more
doaj   +1 more source

The Mechanism of Nitrite Reductase

Journal of Computational Chemistry
ABSTRACT Cytochrome c nitrite reductase (CcNiR) activates nitrite and produces ammonia. It is one of several enzymes that use a redox‐active cofactor to perform its reaction. In this case, the cofactor has a heme with a lysine as the proximal ligand and a charged nearby arginine.
openaire   +2 more sources

Subchronic Exposure to Arsenic and Nickel Triggers Nitrosative Stress and Histological Alterations in the Rat Liver

Journal of Applied Toxicology, EarlyView.
ABSTRACT Environmental exposure to heavy metals poses a threat to human health. Several studies documented harmful effects on the liver after arsenic and nickel exposure at concentrations beyond permissible limits. Nevertheless, the impact of a simultaneous exposure to both elements on hepatic biochemistry and histology remains unelucidated. Therefore,
Thainá Iasbik‐Lima, Luiz Otávio Guimarães‐Ervilha, Isabela Pereira da Silva Bento, Renê Chagas da Silva, Mariana Machado‐Neves   +4 more
wiley   +1 more source

A three-domain copper-nitrite reductase with a unique sensing loop

IUCrJ, 2019
Dissimilatory nitrite reductases are key enzymes in the denitrification pathway, reducing nitrite and leading to the production of gaseous products (NO, N2O and N2).
Diederik Johannes Opperman, Daniel Horacio Murgida, Sergio Daniel Dalosto, Carlos Dante Brondino, Felix Martín Ferroni   +4 more
doaj   +1 more source

Acute Modafinil Exposure Induces Neurobehavioral Alterations in Zebrafish: Implications for Off‐Label Cognitive Enhancement

Journal of Applied Toxicology, EarlyView.
ABSTRACT Modafinil (2‐(benzhydrylsulfinyl)acetamide) is a psychostimulant commonly prescribed for sleep disorders such as narcolepsy, excessive daytime sleepiness, and obstructive sleep apnea. Recently, its use has extended beyond clinical indications, with neurotypical individuals adopting it as a smart drug to enhance alertness and cognitive ...
Luciane Dellazari da Silva do Prado, Nicole Berton, Nicoli da Rosa Amaral, Inara Carbonera Biazus, Laíse Mattiollo, Jéssica Nardi, Karen Júlia de Souza dos Santos, Natália Freddo, Leonardo José Gil Barcellos, Luciana Grazziotin Rossato‐Grando   +9 more
wiley   +1 more source

Comparative modelling and molecular docking of nitrate reductase from Bacillus weihenstephanensis (DS45)

Journal of Taibah University for Science, 2016
Nitrate reductase catalyses the oxidation of NAD(P)H and the reduction of nitrate to nitrite. NR serves as a central point for the integration of metabolic pathways by governing the flux of reduced nitrogen through several regulatory mechanisms in plants,
R. Seenivasagan, R. Kasimani, S. Rajakumar, R. Kalidoss, P.M. Ayyasamy   +4 more
doaj   +1 more source

Effect of ammonium concentration on methane oxidation and CO2 removal in an anaerobic biotrickling filter treating synthetic landfill gas and leachate

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Landfill gas (LFG) and leachate are commonly treated separately through energy‐intensive processes. This study evaluated the integration of both streams in an anaerobic biotrickling filter (BTF) to achieve simultaneous methane (CH4) and carbon dioxide (CO2) removal coupled with ammonium (NH4+) transformation, and how the microbial ...
Cecilia Lizeth Alvarez‐Guzmán, Karla María Muñoz‐Páez, Alejandro Vargas, Idania Valdez‐Vazquez   +3 more
wiley   +1 more source