Results 71 to 80 of about 5,430 (208)

Responsive nitric oxide‐releasing antibacterial materials for biofilm‐associated infections: Mechanisms, design strategies, and applications

Responsive Materials, EarlyView.
This review summarizes the recent progress in responsive NO‐releasing materials and their applications in biofilm‐associated infectious diseases. The design principles and response mechanisms are given to provide inspiration toward the future development of multi‐responsive NO‐releasing materials.
Wenyue Sun, Meiqi Li, Di Nan, Jiaqi Zhao, Yu Chen, Yao Gao, Shichen Zhang, Kirsten L. Van Landuyt, Manlin Qi   +8 more
wiley   +1 more source

Siroheme Is Essential for Assimilation of Nitrate and Sulfate as Well as Detoxification of Nitric Oxide but Dispensable for Murine Virulence of Aspergillus fumigatus

Frontiers in Microbiology, 2018
The saprophytic mold Aspergillus fumigatus is the most common airborne fungal pathogen causing severe invasive fungal infections in immunocompromised patients.
Anna-Maria Dietl, Ulrike Binder, Yana Shadkchan, Nir Osherov, Hubertus Haas   +4 more
doaj   +1 more source

Methaemoglobinaemia: From pathophysiology to contemporary clinical management

British Journal of Haematology, EarlyView.
Summary Methaemoglobin (MetHb) is an oxidised form of haemoglobin (Hb) unable to bind oxygen. Raised levels of MetHb reduce the blood's oxygen‐carrying capacity, causing potentially severe hypoxaemia and possible death. The condition arises from three main pathologies: mutations in globin genes causing Haemoglobin‐M, inherited deficiency of the enzyme ...
Alexander J. Twine, David C. Rees
wiley   +1 more source

SERR Spectroelectrochemical Study of Cytochrome cd1 Nitrite Reductase Co-Immobilized with Physiological Redox Partner Cytochrome c552 on Biocompatible Metal Electrodes.

PLoS ONE, 2015
Cytochrome cd1 nitrite reductases (cd1NiRs) catalyze the one-electron reduction of nitrite to nitric oxide. Due to their catalytic reaction, cd1NiRs are regarded as promising components for biosensing, bioremediation and biotechnological applications ...
Célia M Silveira, Pedro O Quintas, Isabel Moura, José J G Moura, Peter Hildebrandt, M Gabriela Almeida, Smilja Todorovic   +6 more
doaj   +1 more source

Nutrient disturbance in a shallow aquaculture pond impacts Microcystis gene expression but does not impact bacterial community function during bloom conditions

Journal of Phycology, EarlyView.
Abstract Cyanobacterial harmful algal blooms (cHABs) are worldwide issues. Reduced nitrogen forms (ammonium and urea) have recently been measured in freshwater systems at concentrations not previously recorded. These reduced nitrogen forms have been shown to favor the proliferation of harmful cyanobacteria.
Matthew F. Gladfelter, Hunter R. Baylous, Alan E. Wilson, Morgan M. Steffen   +3 more
wiley   +1 more source

Sensing Nitrite through a Pseudoazurin–Nitrite Reductase Electron Transfer Relay

ChemPhysChem, 2005
AbstractNitrite is converted to nitric oxide by haem or copper‐containing enzymes in denitrifying bacteria during the process of denitrification. In designing an efficient biosensor, this enzymic turnover must be quantitatively assessed. The enzyme nitrite reductase from Alcaligenes faecalis contains a redox‐active blue copper centre and a nonblue ...
Astier, Y., Canters, G.W., Davis, J.J., Hill, H.A.O., Verbeet, M.P., Wijma, H.J.   +5 more
openaire   +3 more sources

A QM/MM Study of Nitrite Binding Modes in a Three-Domain Heme-Cu Nitrite Reductase

Molecules, 2018
Copper-containing nitrite reductases (CuNiRs) play a key role in the global nitrogen cycle by reducing nitrite (NO2−) to nitric oxide, a reaction that involves one electron and two protons.
Kakali Sen, Michael A. Hough, Richard W. Strange, Chin W. Yong, Thomas W. Keal   +4 more
doaj   +1 more source

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

Journal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis, James A. Garnett, Richard P. Darveau   +2 more
wiley   +1 more source

Redox Reactivity of Nonsymbiotic Phytoglobins towards Nitrite

Molecules
Nonsymbiotic phytoglobins (nsHbs) are a diverse superfamily of hemoproteins grouped into three different classes (1, 2, and 3) based on their sequences.
Cezara Zagrean-Tuza, Galaba Pato, Grigore Damian, Radu Silaghi-Dumitrescu, Augustin C. Mot   +4 more
doaj   +1 more source

Thaumarchaeal ammonium oxidation and evidence for a nitrogen cycle in a subsurface radioactive thermal spring in the Austrian Central Alps

Frontiers in Microbiology, 2014
Previous studies had suggested the presence of ammonium oxidizing Thaumarchaeota as well as nitrite oxidizing Bacteria in the subsurface spring called Franz Josef Quelle (FJQ), a slightly radioactive thermal mineral spring with a temperature of 43.6 ...
Friedrich Wolfgang Gerbl, Gerhard Wolfgang Weidler, Wolfgang eWanek, Angelika eErhardt, Helga eStan-Lotter   +4 more
doaj   +1 more source