Results 71 to 80 of about 13,465 (259)

In Silico Analysis of the Enzymes Involved in Haloarchaeal Denitrification

Biomolecules, 2021
During the last century, anthropogenic activities such as fertilization have led to an increase in pollution in many ecosystems by nitrogen compounds. Consequently, researchers aim to reduce nitrogen pollutants following different strategies.
Eric Bernabeu, Jose María Miralles-Robledillo, Micaela Giani, Elena Valdés, Rosa María Martínez-Espinosa, Carmen Pire   +5 more
doaj   +1 more source

Multi-heme Cytochromes in Shewanella oneidensis MR-1:Structures, functions and opportunities [PDF]

, 2015
Multi-heme cytochromes are employed by a range of microorganisms to transport electrons over distances of up to tens of nanometers. Perhaps the most spectacular utilization of these proteins is in the reduction of extracellular solid substrates ...
Brown JP, Collins MJ, Coursolle D, Fonseca BM, Jochen Blumberger, Julea N. Butt, Kevin M. Rosso, Marian Breuer, Song Y, Teixeira M   +9 more
core   +1 more source

Proteomics of Nitrotyrosine: Integrating Mass Spectrometry and Immunodetection in Redox‐Driven Pathology

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley   +1 more source

Assessment of Haloferax mediterranei Genome in Search of Copper-Molecular Machinery With Potential Applications for Bioremediation

Frontiers in Microbiology, 2022
Heavy metals are essential micronutrients at low concentrations, serving as cofactors for relevant microbial enzymes (i.e., respiratory nitrate and nitrite reductases NADH dehydrogenase-2, amine oxidase, etc.), but they become harmful cellular ...
Marina García Llorca, Rosa María Martínez-Espinosa, Rosa María Martínez-Espinosa   +2 more
doaj   +1 more source

Reactions of HNO with Metal Porphyrins: Underscoring the Biological Relevance of HNO [PDF]

, 2014
Azanone (1 HNO, nitroxyl) shows interesting yet poorly understood chemical and biological effects. HNO has some overlapping properties with nitric oxide (NO), sharing its biological reactivity toward heme proteins, thiols, and oxygen.
Bikiel, Damian Ezequiel, Doctorovich, Fabio, Marti, Marcelo Adrian, Pellegrino, Juan, Suarez, Sebastian   +4 more
core   +1 more source

Rieske Iron–Sulfur Cluster Proteins From an Anaerobic Ammonium Oxidizer Suggest Unusual Energetics in Their Parent Rieske/Cytochrome b Complexes

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Anaerobic ammonium‐oxidizing (anammox) bacteria employ a unique, hydrazine‐based pathway to obtain energy from nitrite and ammonium. These organisms possess distinct Rieske/cytochrome b complexes whose precise role in anammox metabolism remains unclear, but which have been proposed to include the generation of NAD(P)H.
David Hauser, Mandy Sode, Elena A. Andreeva, Kristian Parey, Thomas R. M. Barends   +4 more
wiley   +1 more source

Indirect Antioxidant Effects of the Nitrite Anion: Focus on Xanthine Oxidase

Advances in Redox Research, 2023
One electron reduction of nitrite (NO2−) has been determined to be a significant, noncanonical source of nitric oxide (NO) with molybdopterin enzymes being identified as critical to this process. Of the molybdopterin enzymes identified as NO2− reductases,
Xena M. Williams, Alec T. Bossert, Evan Devalance, Sara E. Lewis, Michael R. Gunther, Eric E. Kelley   +5 more
doaj   +1 more source

Biochemical properties of Paracoccus denitrificans FnrP:Reactions with molecular oxygen and nitric oxide [PDF]

, 2016
In Paracoccus denitrificans, three CRP/FNR family regulatory proteins, NarR, NnrR and FnrP, control the switch between aerobic and anaerobic (denitrification) respiration.
A Volbeda, A Yan, AJ Jervis, Andrew J. Thomson, AS Fleischhacker, B Weiss, B Zhang, CP Tseng, CT Przysiecki, CV Popescu, D Ralt, DJ Richardson, DJ Shaw, DM Bates, F Sievers, G Sawers, H Beinert, H Reents, J Crack, J Edwards, J Green, Jason C. Crack, JC Crack, JC Crack, JC Crack, JC Crack, JC Crack, JC Crack, JC Crack, JC Crack, JC Crack, JC Drapier, L Bergaust, LJ Moore, LR Bakken, M Matsui, Matthew I. Hutchings, MC Broillet, MF Otten, MI Hutchings, MI Hutchings, MM Bradford, N Filenko, Nick E. Le Brun, NJ Watmough, P Bouchal, PJ Kiley, R Bruckdorfer, R Veldman, RJ Spanning Van, RJ Spanning van, SA Ibrahim, SB Melville, ST Pullan, VR Sutton, WG Zumft, YM Kwon, YY Lee   +57 more
core   +1 more source

Distribution and activity of nitrate and nitrite reductases in the microbiota of the human intestinal tract

The FEBS Journal, EarlyView.
Nitrate from food is first converted to nitrite by oral bacteria and then further processed in the intestine. The gut microbiota reduces nitrate and nitrite to ammonia or nitric oxide, preventing the formation of carcinogenic nitrosamines. Our analysis highlights Escherichia coli as a key player in this detoxification process, supported by other ...
Natalie Hager, Mélanie Elisabeth Gindt, Marcel Hövels, Jean‐Lou Christian Michel Dorne, Uwe Deppenmeier   +4 more
wiley   +1 more source

E. coli and gut health—For the loser now will be later to win

The FEBS Journal, EarlyView.
In humans, commensal gut bacteria participate in a miniature nitrogen cycle, metabolizing dietary nitrate and nitrite. While these processes can generate harmful N‐nitrosamines, they may also produce beneficial nitric oxide (NO) or ammonium. Hager and colleagues demonstrate that E.
Jon O. Lundberg
wiley   +1 more source