Methods to assemble axially chiral biaryl molecules with nitrogen-containing heterocycles can have implications in ligand development for homogeneous catalysis. Here the authors report enantioselective syntheses of axially chiral arylquinolizones, via an
Xiao-Long Min +3 more
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How Not to Discover a New Reagent. The Evolution and Chemistry of Woollins' Reagent [PDF]
The pathways in research can be complex. This review provides a personal account of the winding scientific and funding road that led to Woollins' reagent.
Woollins, J. Derek
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Preparation of Antimicrobial Nitrogen Heterocycles Using Sustainable Processes
Libraries of compounds containing heteroaromatic rings and other nitrogen heterocycles were [...]
Concepción C. González +4 more
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Decoration of A-Ring of a Lupane-Type Triterpenoid with Different Oxygen and Nitrogen Heterocycles
Betulinic acid (BA) was used as starting building block to create a library of novel BA-derived compounds containing O- and N-heterocycles. Firstly, BA was converted into methyl betulonate (BoOMe), which was used as intermediate in the developed ...
Joana L. C. Sousa +3 more
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Synthesis of Enantiopure Oxygen- and Nitrogen-Containing Heterocycles by Diastereoselective Ring-Closing Metathesis Reaction in Perhydro-1,3-benzoxazine Derivatives [PDF]
Producción CientíficaDiastereoselective ring‐closing metathesis reactions on chiral trienic perhydro‐1,3‐benzoxazines derived from (−)‐8‐aminomenthol featuring two diastereotopic olefin chains is described.
Andrés Juan, Celia +4 more
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Hydrazones as Singular Reagents in Asymmetric Organocatalysis [PDF]
This Minireview summarizes strategies and developments regarding the use of hydrazones as reagents in asymmetric organocatalysis, their distinct roles in nucleophile–electrophile, cycloaddition, and cyclization reactions.
Fernández Fernández, Rosario Fátima +4 more
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Diquaternary Ammonium Compounds in Zeolite Synthesis: Cyclic and Polycyclic N-Heterocycles Connected by Methylene Chains [PDF]
An additional dimension has been added to our long-standing studies in high silica zeolite synthesis via a guest/host synergism. We have created and studied the impact of making symmetric diquaternary ammonium compounds, by varying the chain length ...
Burton, Allen W. +3 more
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Transfer of electrophilic NH using convenient sources of ammonia: direct synthesis of N–H sulfoximines from sulfoxides [PDF]
The transfer of nitrogen atoms is extremely valuable in the preparation of medicinal compounds. Here, a new system for NH transfer is developed to prepare sulfoximines, which are emerging as valuable motifs for drug discovery.
Bentley +43 more
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Nitrogen-containing heterocycles such as quinazolines and benzofurans have received a great amount of interest in targeted therapies as antitumor drugs [1]. [...]
Marole Maria Maluleka +1 more
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Asymmetric addition of chiral boron-ate complexes to cyclic iminium ions [PDF]
Boron-ate complexes derived from enantioenriched secondary benzylic boronic esters and aryl lithiums have been reacted with quinolinium, pyridinium and dihydroisoquinolinium salts to give enantioenriched heterocyclic structures with very high ...
Aggarwal, Varinder K. +4 more
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