Results 51 to 60 of about 3,582,154 (355)

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

A data-driven reduced-order model for fast prediction of resonant acoustic flow under vertical vibration based on secondary decomposition

AIP Advances
Accurate dimensionality reduction models are crucial for constructing real-time computational digital twin systems for process equipment. To deepen the understanding of acoustic resonance flow mechanisms and optimize equipment design, a high-precision ...
Yuqi Gao, Ning Ma, Shifu Zhu, Pengchao Zhang, Hongxing Liu, Zhongyuan Xie   +5 more
doaj   +1 more source

Ionized Nitrogen Mono-hydride Bands are Identified in the Pre-solar and Carbonado Diamond Spectra

, 2011
None of the well established Nitrogen related IR absorption bands, common in synthetic and terrestrial diamonds, have been identified in the pre-solar diamond spectra.
Adams, Amari, Anders, Andersen, Braatz, Cheung, Colangeli, Collins, Crawford, Davis, Demeny, Field, Garai, Hill, Hily-Blant, Huebner, Jones, Jones, Kagi, Koike, Lawson, Lawson, Lewis, Lewis, McNamara, Meier, Meyer, Mitchell, Mutschke, Mutschke, Persson, Samoilovitch, Schmitt, Swings   +33 more
core   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Measures to achieve a stable farming system in sustainable agriculture – a short review

Annales Universitatis Paedagogicae Cracoviensis Studia Naturae, 2019
Zrównoważony system rolny jest najlepszym sposobem na zaspokojenie potrzeb dzisiejszych i przyszłych pokoleń. W systemie tym wielkość plonu wzrasta wraz z zastosowaniem upraw międzyrzędowych, poprzez wyższy współczynnik wzrostu roślin, redukcję nasion ...
Mohamad Hesam Shahrajabian, Wenli Sun, Qi Cheng   +2 more
doaj   +1 more source

Titan's past and future: 3D modeling of a pure nitrogen atmosphere and geological implications

, 2014
Several clues indicate that Titan's atmosphere has been depleted in methane during some period of its history, possibly as recently as 0.5-1 billion years ago. It could also happen in the future.
Charnay, Benjamin, Forget, François, Sotin, Christophe, Tobie, Gabriel, Wordsworth, Robin   +4 more
core   +3 more sources

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Condensation of 4-Tert-butyl-2,6-dimethylbenzenesulfonamide with Glyoxal and Reaction Features: A New Process for Symmetric and Asymmetric Aromatic Sulfones

Molecules, 2022
The synthesis of substituted aza- and oxaazaisowurtzitanes via direct condensation is challenging. The selection of starting ammonia derivatives is very limited.
Artyom E. Paromov, Sergey V. Sysolyatin, Irina A. Shchurova   +2 more
doaj   +1 more source

A NITROGEN GENERATOR. [PDF]

Journal of the American Chemical Society, 1914
n ...
openaire   +2 more sources

Effects of Nitrogen Fertilization on Monoterpenes of Jack Pine Seedlings and Weight Gain of Jack Pine Budworm (Lepidoptera: Tortricidae) [PDF]

, 2017
Nine-month old jack pine (Pinus banksiana) seedlings were grown in a greenhouse under four nitrogen fertilization regimes. Levels of total nitrogen and five monoterpenes in new foliage were measured. Fertilization resulted in four significantly different
Kulman, Herbert M, McCullough, Deborah G, Swedenborg, Paul D   +2 more
core   +2 more sources