Results 11 to 20 of about 49,782 (284)
Nitrogen Containing Heterocycles as Anticancer Agents: A Medicinal Chemistry Perspective
Pharmaceuticals, 2023 Cancer is one of the major healthcare challenges across the globe. Several anticancer drugs are available on the market but they either lack specificity or have poor safety, severe side effects, and suffer from resistance.
Adarsh Kumar +14 more
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N-tert-Butanesulfinyl imines in the asymmetric synthesis of nitrogen-containing heterocycles
Beilstein Journal of Organic Chemistry, 2021 The synthesis of nitrogen-containing heterocycles, including natural alkaloids and other compounds presenting different types of biological activities have proved to be successful employing chiral sulfinyl imines derived from tert-butanesulfinamide ...
Joseane A. Mendes +4 more
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Molecules, 2023 Nitrogen-containing heterocycles are ubiquitous in natural products and drugs. Various organic small molecules with nitrogen-containing heterocycles, such as nitrogen-containing boron compounds, cyanine, pyridine derivatives, indole derivatives ...
Yanan Li, Tao Liu, Jianan Sun
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Frontiers in Chemistry, 2022 The C-H functionalization of nitrogen-containing heterocycles has emerged as a powerful strategy for the construction of carbon-carbon (C-C) and carbon-heteroatom (C-X) bonds.
Ya-Nan Li +4 more
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A Review on Recent Advances in Nitrogen-Containing Molecules and Their Biological Applications
Molecules, 2020 The analogs of nitrogen-based heterocycles occupy an exclusive position as a valuable source of therapeutic agents in medicinal chemistry. More than 75% of drugs approved by the FDA and currently available in the market are nitrogen-containing ...
Nagaraju Kerru +4 more
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Pharmaceutics, 2023 Five-membered heterocycles are essential structural components in various antibacterial drugs; the physicochemical properties of a five-membered heterocycle can play a crucial role in determining the biological activity of an antibacterial drug.
Aura Rusu +3 more
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Fused 1,5-Naphthyridines: Synthetic Tools and Applications
Molecules, 2020 Heterocyclic nitrogen compounds, including fused 1,5-naphthyridines, have versatile applications in the fields of synthetic organic chemistry and play an important role in the field of medicinal chemistry, as many of them have a wide range of biological ...
Carme Masdeu +6 more
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Predicting Solid-State Heats of Formation of Newly Synthesized Polynitrogen Materials by Using Quantum Mechanical Calculations [PDF]
, 2008 We present density functional theory level predictions and analysis of the basic properties of newly synthesized high-nitrogen compounds together with 3,6-bis(2H-tetrazol-5-yl)-1,2,4,5-tetrazine (BTT) and 3,3′-azobis(6-amino-1,2,4,5-tetrazine) (DAAT ...
Abou-Rachid, H. +5 more
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Nitrogen heterocycles from trimethylbenzenes
Heteroatom Chemistry, 2004 AbstractThe reaction between 1,2,4‐trimethylbenzene 1, isobutyric aldehyde, and cyanoacetic ester afforded a mixture of three products: 3,3,5,6,8‐ pentamethyl‐1,2,3,4‐tetraisoquinolylidene‐1‐acetic acid ether (2) and its 3,3,5,6,7‐pentamethyl‐(3)‐ and 3,3,6,7,8‐pentamethyl‐1,2,3,4‐tetraisoquinolyli‐ dene‐1‐acetic acid ether isomers (3) in ratio 1:5:1. ©
Yu. V. Shklyaev +6 more
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An electron-deficient triosmium cluster containing the thianthrene ligand: Synthesis, structure and reactivity of [Os₃(CO)₉(μ3-η2-C₁₂H₇S₂)(μ-H)] [PDF]
, 2008 Reaction of [Os₃(CO)₁₀(CH₃CN)₂] with thianthrene at 80 °C leads to the nonacarbonyl dihydride compound [Os₃(CO)₉(μ-3,4-η²-C₁₂H₆S₂)(μ-H)₂] (1) and the 46-electron monohydride compound [Os₃(CO)₉(μ₃-η²-C₁₂H₇S₂)(μ-H)] (2).
Hassan, Mohammad R. +7 more
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