Results 11 to 20 of about 922,646 (221)

Preparation of Antimicrobial Nitrogen Heterocycles Using Sustainable Processes

open access: yesProceedings, 2017
Libraries of compounds containing heteroaromatic rings and other nitrogen heterocycles were [...]
Concepción C. González   +4 more
doaj   +2 more sources

Biosynthesis of oxygen and nitrogen-containing heterocycles in polyketides [PDF]

open access: yesBeilstein Journal of Organic Chemistry, 2016
This review highlights the biosynthesis of heterocycles in polyketide natural products with a focus on oxygen and nitrogen-containing heterocycles with ring sizes between 3 and 6 atoms.
Franziska Hemmerling, Frank Hahn
doaj   +2 more sources

Synthesis and Applications of Nitrogen-Containing Heterocycles as Antiviral Agents

open access: yesMolecules, 2022
Viruses have been a long-term source of infectious diseases that can lead to large-scale infections and massive deaths. Especially with the recent highly contagious coronavirus (COVID-19), antiviral drugs were developed nonstop to deal with the emergence
Tuyen N. Tran, Maged Henary
doaj   +2 more sources

Highly Efficient and Reusable Copper-Catalyzed N-Arylation of Nitrogen-Containing Heterocycles with Aryl Halides

open access: yesMolecules, 2009
CuO/AB was found to be a simple and efficient catalyst for the N-arylation of a variety of nitrogen-containing heterocycles, giving the products in excellent yields.
Kang Hyun Park   +6 more
doaj   +2 more sources

N-tert-Butanesulfinyl imines in the asymmetric synthesis of nitrogen-containing heterocycles

open access: yesBeilstein Journal of Organic Chemistry, 2021
The synthesis of nitrogen-containing heterocycles, including natural alkaloids and other compounds presenting different types of biological activities have proved to be successful employing chiral sulfinyl imines derived from tert-butanesulfinamide ...
Joseane A. Mendes   +4 more
doaj   +1 more source

Recent Advances in N-Heterocyclic Small Molecules for Synthesis and Application in Direct Fluorescence Cell Imaging

open access: yesMolecules, 2023
Nitrogen-containing heterocycles are ubiquitous in natural products and drugs. Various organic small molecules with nitrogen-containing heterocycles, such as nitrogen-containing boron compounds, cyanine, pyridine derivatives, indole derivatives ...
Yanan Li, Tao Liu, Jianan Sun
doaj   +1 more source

A Review on Recent Advances in Nitrogen-Containing Molecules and Their Biological Applications

open access: yesMolecules, 2020
The analogs of nitrogen-based heterocycles occupy an exclusive position as a valuable source of therapeutic agents in medicinal chemistry. More than 75% of drugs approved by the FDA and currently available in the market are nitrogen-containing ...
Nagaraju Kerru   +4 more
doaj   +1 more source

Recent advances in metal catalyst- and oxidant-free electrochemical C-H bond functionalization of nitrogen-containing heterocycles

open access: yesFrontiers in Chemistry, 2022
The C-H functionalization of nitrogen-containing heterocycles has emerged as a powerful strategy for the construction of carbon-carbon (C-C) and carbon-heteroatom (C-X) bonds.
Ya-Nan Li   +4 more
doaj   +1 more source

The Role of Five-Membered Heterocycles in the Molecular Structure of Antibacterial Drugs Used in Therapy

open access: yesPharmaceutics, 2023
Five-membered heterocycles are essential structural components in various antibacterial drugs; the physicochemical properties of a five-membered heterocycle can play a crucial role in determining the biological activity of an antibacterial drug.
Aura Rusu   +3 more
doaj   +1 more source

Fused 1,5-Naphthyridines: Synthetic Tools and Applications

open access: yesMolecules, 2020
Heterocyclic nitrogen compounds, including fused 1,5-naphthyridines, have versatile applications in the fields of synthetic organic chemistry and play an important role in the field of medicinal chemistry, as many of them have a wide range of biological ...
Carme Masdeu   +6 more
doaj   +1 more source

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