Fused 1,5-Naphthyridines: Synthetic Tools and Applications
Molecules, 2020 Heterocyclic nitrogen compounds, including fused 1,5-naphthyridines, have versatile applications in the fields of synthetic organic chemistry and play an important role in the field of medicinal chemistry, as many of them have a wide range of biological ...
Carme Masdeu +6 more
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Synthesis of α‐Trifluoromethylated Nitrogen Heterocycles. [PDF]
ChemInform, 2003 AbstractFor Abstract see ChemInform Abstract in Full Text.
Ségolène, Gille +3 more
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Synthesis of unprotected nitrogen-containing heterocycles via Aza Heck reactions
, 2022 Watson, Donald A.The main objective of this thesis is centered around the identification of novel amide electrophiles for the development of aza-Heck-type reactions.
Shuler, Scott Adam
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Insertion of ammonia into alkenes to build aromatic N-heterocycles
Nature Communications, 2022 Aromatic heterocycles containing nitrogen are ubiquitous in biologically relevant small molecules. Here the authors show an unorthodox methodology for their synthesis, by inserting the nitrogen atom into a carbon ring, with ammonia in electrochemical ...
Shuai Liu, Xu Cheng
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Nitrogen heterocycles from trimethylbenzenes
Heteroatom Chemistry, 2004 AbstractThe reaction between 1,2,4‐trimethylbenzene 1, isobutyric aldehyde, and cyanoacetic ester afforded a mixture of three products: 3,3,5,6,8‐ pentamethyl‐1,2,3,4‐tetraisoquinolylidene‐1‐acetic acid ether (2) and its 3,3,5,6,7‐pentamethyl‐(3)‐ and 3,3,6,7,8‐pentamethyl‐1,2,3,4‐tetraisoquinolyli‐ dene‐1‐acetic acid ether isomers (3) in ratio 1:5:1. ©
Yu. V. Shklyaev +6 more
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The Nitrogen Heterocycle Content of Meteorites and Their Significance for the Origin of Life
Life, 2018 Carbonaceous chondrites are very primitive meteorites that are rich in carbon. They contain many soluble organic compounds, including nitrogen heterocycles.
Zita Martins
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Oxime derivatives : versatile reagents for radical-mediated syntheses of heterocycles [PDF]
, 2010 A summary of tin hydride mediated reactions in generating radicals in organic synthesis is presented, together with some of the many alternative methods now available for conducting radical reactions.
Portela-Cubillo, Fernando
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Atropisomerism in Boron-Nitrogen Heterocycles/Atropisomerism in Boron-Nitrogen Heterocycles
Zeitschrift für Naturforschung B, 1987 Abstract Atropisomerism owing to hindered rotation about the N-aryl bond is observed in 4,5-diethyl-2,2,3-trimethyl-1-(o-trifluormethyl)phenyl-2,5-dihydro-1H-1,2,5-azasila-(2) and -azastanna-boroles (5). The compounds 2 and 5 are characterized by elemental analysis, mass spectra and 1H, 11B, 13 C, 29Si and119Sn NMR.
Roland Köster +3 more
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Various Synthesis of Imidazo[1,2-a]pyridines Derivatives and Therapeutic Significance: A Review [PDF]
BIO Web of ConferencesThe synthesis of bicyclic heterocycles, notably nitrogen-containing imidazopyridines, holds immense appeal due to their structural diversity and pivotal role in biological systems. These compounds are ubiquitously found in nature and are prized for their
Hamdi Abdeljalil +7 more
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Synthesis of arylamines and N-heterocycles by direct catalytic nitrogenation using N2
Nature Communications, 2021 Ammonia and nitric acid are key platform chemicals to introduce nitrogen into organic molecules, however gaseous N2 would be a more direct and available source of nitrogen.
Kai Wang +5 more
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