Results 61 to 70 of about 922,646 (221)
Interesting Mechanistic Approach for Nitrogen Heterocycles of Industrial Importance
, 2018 Nitrogen heterocycles have played an important role in different industrial sectors.Porphyrins the macrocyclic compounds containing pyrrole rings provide an extremely versatile platform with desired peripheral functionality and metal complexes to form ...
K.Z. Khan, N.D. Zargar
core +1 more source
Liquid‐Responsive Shape‐Memory Nanofiber‐Reinforced Scaffolds for Cartilage Repair
Advanced Science, EarlyView.A liquid‐responsive shape‐memory, nanofiber‐reinforced QCG scaffold combines conformal defect filling, an aligned architecture that is structurally permissive for endogenous cell infiltration, and sustained KGN release. This integrated design enhances BMSC viability, migratory activity, and chondrogenic differentiation and promotes hyaline cartilage ...
Jiyang Zeng +8 more
wiley +1 more source
Recent advances in metal-free catalysts for the synthesis of N-heterocyclic frameworks focusing on 5- and 6-membered rings: a review [PDF]
RSC AdvancesThe tremendous potential of transition metal-free multi-component reactions (MCR) in the synthesis of N-heterocyclic frameworks is examined in this review, offering a complete overview of this subject matter.
Hai Truong Nguyen +4 more
doaj +1 more source
Unlocking Li/Mg‐Based Photochemical Nitration Platforms for Anticancer Drug Discovery
Advanced Science, EarlyView.Two low‐toxicity light main‐group metal photochemical systems based on lithium and magnesium are constructed for selective C(sp2)‐H (di)nitration of anilines. The obtained dinitrated products exhibit anti‐HCC (hepatocellular carcinoma) and anti‐KYSE30 cell activities, holding promise as novel antitumor candidates.
Qian Wan +13 more
wiley +1 more source
Angewandte Chemie, EarlyView.Azamacrocycles provide a tunable platform for rapid N‐carboxyanhydride (NCA) Ring‐Opening Polymerization (ROP). Changing the methylation pattern switches the macrocycle from an external catalyst (N14Me3) to a covalent initiator‐catalyst (IniCat, N14Me1), delivering controlled polypeptide growth under open‐vessel conditions.
Paulina Maksym +10 more
wiley +2 more sources
Benzotriazole-Mediated Synthesis of Nitrogen-Containing Heterocycles
, 2015 Application of benzotriazole methodology for the preparation of nitrogen-containing heterocyclic compounds is summarized in this review. The characteristic advantages of benzotriazole are first briefly considered followed by an overview of its use in the
Judit K. Beagle, Beagle, Judit K.
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Advanced Science, EarlyView.The C3‐symmetric conjugate TASe, which integrates benzoselenadiazole, alanine, and acylhydrazone modules, self‐assembles into a chalcogen‐/hydrogen‐bonded porous framework in the solid state and uniform chiral nanospheres in aqueous media. These assemblies protect cardiomyocytes from doxorubicin‐induced oxidative injury by scavenging intracellular ...
Jinkui Teng +11 more
wiley +1 more source
Chemical Inhibition of Pyocyanin Biosynthesis Attenuates Virulence of Pseudomonas aeruginosa
Angewandte Chemie, EarlyView.Anti‐virulence strategies disarm pathogens rather than killing them directly. A β‐lactone reduces pyocyanin production without affecting growth. Chemical proteomics identified PqsC as the primary target via binding to Cys129. Crystallography revealed the binding mode, and SAR yielded a chloroacetamide inhibitor with improved enzymatic potency and anti ...
Wei Ding +3 more
wiley +2 more sources
Journal of ChemistryIn recent years, there has been a significant surge in the catalytic utilization of Schiff–base complexes. These compounds prove to be highly effective as homogeneous catalysts in organic syntheses.
Mehdi Fallah-Mehrjardi, Soheil Sayyahi
doaj +1 more source
New Method Development to Streamline the Synthesis of N-Heterocycles
, 2017 Nitrogen-heterocycles are an important class of molecules because of its widespread availability in pharmaceuticals, natural products and organic electronic materials.
Navendu Jana (1312224)
core