Results 81 to 90 of about 871,548 (248)
Direct Access to Chiral Piperidines by Enantioselective HAT‐Initiated C(sp3)─H Oxidation
Angewandte Chemie, EarlyView.The direct desymmetrization of piperidines is achieved through manganese‐catalyzed enantioselective α‐C(sp3)─H oxidation with hydrogen peroxide, affording versatile chiral N,O‐acetals in good yields and with high enantio‐ and diastereoselectivity. These intermediates provide access to diverse functionalized piperidines with retention of chirality ...
Sethuraman Muthuramalingam +5 more
wiley +2 more sources
Advanced Science, EarlyView.In this review, the classification and development history of the volatile solid and solvent additives are comprehensively summarized, the underlying mechanisms of morphology optimization are discussed, and a summary of volatile additive‐induced improvements in interfacial layer performance is provided.
Jianqiang Qin +7 more
wiley +1 more source
Results in Surfaces and InterfacesOrganic compounds containing heteroatoms have been recognized for their significant ability to mitigate corrosion through adsorption facilitated by lone pair and π–electron interactions with metallic surfaces.
Tlabo Caiphus Leboho +4 more
doaj +1 more source
Strained Small Nitrogen Heterocycles‐Azabicyclobutanes and Azirines
, 2023 Small ring nitrogen heterocycles, azabicyclobutanes and azirines, were investigated by computational methods in order to address the discrepancy between their regioisomers 1- and 2-azabicyclobutane and 1H- and 2H-azirines.
Fiser, Bela (Phd) +7 more
core +1 more source
Unlocking Li/Mg‐Based Photochemical Nitration Platforms for Anticancer Drug Discovery
Advanced Science, EarlyView.Two low‐toxicity light main‐group metal photochemical systems based on lithium and magnesium are constructed for selective C(sp2)‐H (di)nitration of anilines. The obtained dinitrated products exhibit anti‐HCC (hepatocellular carcinoma) and anti‐KYSE30 cell activities, holding promise as novel antitumor candidates.
Qian Wan +13 more
wiley +1 more source
Enhancement of Dissymmetry Factors Through Axial Elongation of Hetero[n]helicenes
Angewandte Chemie, EarlyView.A benzofuran scaffolding strategy enables the synthesis of hetero[9]‐, [12]‐, and [15]helicenes. Structural and chiroptical analyses demonstrate that systematic axial elongation increases helical distortion and significantly amplifies luminescence dissymmetry.
Jeppe S. Mogensen +7 more
wiley +2 more sources
Synthesis of six membered heterocycles containing nitrogen or oxygen [PDF]
, 2017 Six-membered heterocycles containing nitrogen and oxygen are prevalent in natural products and pharmaceutical drugs; hence efficient synthesis of these motifs is of great benefit.
Turner, Peter G.
core +1 more source
Advanced Intelligent Discovery, EarlyView.This research demonstrates that the combination of domain knowledge–based multiple regression, multi‐objective Bayesian optimization, and generative models is a suitable prediction tool for candidates of high refractive index polymers, even with the constraints in the model trained on limited data. The experimental validation can reproduce the proposed
Takuya Yokoo +3 more
wiley +1 more source
Angewandte Chemie, EarlyView.A metal‐free photocatalytic platform converts nitrones into 4‐isoxazolines and oxa–aza–bicycloheptanes through divergent [3+2π/σ] cycloadditions. Assembly‐controlled kinetic electron transfer gating dictates substrate activation, enabling selective reactivity beyond thermodynamic expectations.
Nayan Saha +6 more
wiley +2 more sources
MoleculesThe journal retracts the article titled “Fluorescent and Phosphorescent Nitrogen-Containing Heterocycles and Crown Ethers: Biological and Pharmaceutical Applications” [...]
Faiz Ullah +8 more
doaj +1 more source