Results 81 to 90 of about 922,646 (221)

Lewis Acid‐Catalyzed Strain‐Enabled (3+3) Annulation of Bicyclo[1.1.0]Butanes With Indolylalcohols: Synthesis of Indole‐Fused Aza‐Bicyclo[3.1.1]Heptanes

Advanced Science, EarlyView.
Bicyclo[1.1.0]butanes undergo a Lewis acid‐catalyzed formal (3 + 3) annulation with indolyl alcohols to furnish indole‐fused aza‐bicyclo[3.1.1]heptanes. Strain‐release‐driven C‐C bond formation, followed by C‐N bond formation via ring expansion, enables the rapid assembly of rigid, sp3‐rich bicyclic architectures under mild reaction conditions ...
Mainak Dey, Tuhin Subhra Das Mahapatra, Pragya Sharma, Manoj V. Mane, Chinmoy Kumar Hazra   +4 more
wiley   +1 more source

1‐Azabicyclo[1.1.0]butanes (ABBs) on the Map: Mechanistic Pathways for Catalytic Ring Opening and Functionalizations

Angewandte Chemie, EarlyView.
Catalytic strain‐release ring opening and functionalizations of 1‐azabicyclo[1.1.0]butanes (ABBs) represent a promising strategy for accessing diverse azetidine products. These transformations proceed via polar pathways, radical pathways, and hybrid mechanisms that combine both.
James Shao‐Jiun Yang, Hsuan‐Hung Liao   +1 more
wiley   +2 more sources

Palladium-Catalyzed Modular Synthesis of Substituted Piperazines and Related Nitrogen Heterocycles

, 2016
We report here a novel method for the modular synthesis of highly substituted piperazines and related bis-nitrogen heterocycles via a palladium-catalyzed cyclization reaction.
Thomas D. Montgomery (1325580), Viresh H. Rawal (1323897)   +1 more
core   +1 more source

Photochemical Regiodivergent Functionalization of Quinolines with Aryl Ketones

Advanced Science, EarlyView.
A photocatalytic system‐controlled approach enables regiodivergent C2‐ and C4‐functionalization of quinolines with aryl ketones by optimizing aryl thiol photocatalysts and formate reductants. Using ortho‐(isopropoxycarbonyl)thiophenol with excess formate facilitates C4‐dearomatization, yielding bridged 1,3‐oxazepanes. In contrast, meta‐(methoxycarbonyl)
Yi‐Lin Zhao, Bei‐Bei Zhang, Xueying Guo, Kui Dong, Zhi‐Xiang Wang, Li‐Zhu Wu, Qiang Liu   +6 more
wiley   +1 more source

Synthesis and Preliminary Antimicrobial Study of 2-Amino-5-Mercapto-1,3,4-Thiadiazole Derivatives

Iraqi Journal of Pharmaceutical Sciences, 2017
Nitrogen heterocycles are of a special interest because they constitute an important class of natural and non natural products, many of which exhibit useful biological activities.Among these nitrogen heterocycles are 1, 3, 4-thiadiazole containing ...
Husam A. Ameen, Ahlam J. Qasir
doaj   +3 more sources

Second‐Sphere Aromatic Substitutions That Tune H‐Atom Transfer Reactivity Observed for a Series of S = 1 Nonheme FeIV=O Complexes: An Enthalpy‐Entropy Compensation Effect

Angewandte Chemie, EarlyView.
A series of oxoiron(IV) complexes was synthesized to determine the impact of electronically tuned aromatic substitution in the secondary sphere of the ligand. Despite possessing identical electronic properties, they show significant differences in C─H oxidation reactions.
Abhishek Das, Jin Xiong, Victor G. Young Jr., Yisong Guo, Marcel Swart, Lawrence Que Jr.   +5 more
wiley   +2 more sources

An In–Depth exploration of pyrazole, imidazole, and triazole derivatives, showcasing their unparalleled effectiveness as dynamic organic corrosion inhibitors in aqueous environments

Results in Surfaces and Interfaces
Organic compounds containing heteroatoms have been recognized for their significant ability to mitigate corrosion through adsorption facilitated by lone pair and π–electron interactions with metallic surfaces.
Tlabo Caiphus Leboho, Kgaugelo Selowa, Reginald Khomotso Mothapo, Thabo Pesha, Bryan Phuti Moloto   +4 more
doaj   +1 more source

Generative and Experimental Validation of High Refractive Index Polymers via Domain Knowledge Approach with Small Data

Advanced Intelligent Discovery, EarlyView.
This research demonstrates that the combination of domain knowledge–based multiple regression, multi‐objective Bayesian optimization, and generative models is a suitable prediction tool for candidates of high refractive index polymers, even with the constraints in the model trained on limited data. The experimental validation can reproduce the proposed
Takuya Yokoo, Seigo Watanabe, Hana Matsunaga, Kenichi Oyaizu   +3 more
wiley   +1 more source

Access to Unsupported Iminobismuthane and Tetraazabismole Species Enabled by a Rigid and Bulky Organobismuthinidene

Angewandte Chemie, EarlyView.
By employing a sterically bulky monocoordinate bismuthinidene, the synthesis and characterization of the first examples of an unsupported iminobismuthane and tetraazabismole was achieved via reactions with organic azides. The corresponding amines could be accessed by reduction, leading to the regeneration of the Bi(I) compound. Hence, we also highlight
Marcel Potocnik, Kristian L. Mears, Davide Spinnato, Gabriele Deplano, Nils Nöthling, Markus Leutzsch, Maurice van Gastel, Khai‐Nghi Truong, Serena DeBeer, Josep Cornella   +9 more
wiley   +2 more sources

RETRACTED: Ullah et al. Fluorescent and Phosphorescent Nitrogen-Containing Heterocycles and Crown Ethers: Biological and Pharmaceutical Applications. Molecules 2022, 27, 6631

Molecules
The journal retracts the article titled “Fluorescent and Phosphorescent Nitrogen-Containing Heterocycles and Crown Ethers: Biological and Pharmaceutical Applications” [...]
Faiz Ullah, Sami Ullah, Muhammad Farhan Ali Khan, Muhammad Mustaqeem, Rizwan Nasir Paracha, Muhammad Fayyaz ur Rehman, Fariha Kanwal, Syed Shams ul Hassan, Simona Bungau   +8 more
doaj   +1 more source