Results 91 to 100 of about 871,548 (248)

Access to Unsupported Iminobismuthane and Tetraazabismole Species Enabled by a Rigid and Bulky Organobismuthinidene

Angewandte Chemie, EarlyView.
By employing a sterically bulky monocoordinate bismuthinidene, the synthesis and characterization of the first examples of an unsupported iminobismuthane and tetraazabismole was achieved via reactions with organic azides. The corresponding amines could be accessed by reduction, leading to the regeneration of the Bi(I) compound. Hence, we also highlight
Marcel Potocnik, Kristian L. Mears, Davide Spinnato, Gabriele Deplano, Nils Nöthling, Markus Leutzsch, Maurice van Gastel, Khai‐Nghi Truong, Serena DeBeer, Josep Cornella   +9 more
wiley   +2 more sources

Chiral hypervalent iodine catalyzed stereoselective skeletal editing of pyrimidine fused heterocycles

Nature Communications
In the realm of molecular construction, the skeletal editing techniques of heterocyclic compounds demonstrate unique efficiency, particularly in synthesizing molecular structures that are challenging to obtain through traditional synthetic methods ...
Wen-Wu Sun, Yi-Bing Xie, Bin Wu
doaj   +1 more source

A Mesoionic Platform for Persistent Anionic Nitrogen‐Centered Radicals

Angewandte Chemie, EarlyView.
Charge did not meet spin: Mesoionic 1,2,3‐triazines undergo reversible one‐electron reduction to persistent anionic nitrogen‐centered radicals. Electron paramagnetic resonance, single‐crystal x‐ray diffraction, and calculations reveal nitrogen‐localized spin and structural reorganization, while crystalline salts show clean redox cycling.
Deepak Ranolia, Aleksandr Koronatov, Yogendra Kumar, Mamta Sham Lal, Boris Tumansky, Alexander Kaushansky, Natalia Fridman, Malachi Noked, Mark Gandelman   +8 more
wiley   +2 more sources

Cobalt‐Catalyzed C─N Bond Formation via Metal‐Hydride Hydrogen Atom Transfer (MHAT)

Angewandte Chemie, EarlyView.
Cobalt‐catalyzed metal‐hydride hydrogen atom transfer (Co‐MHAT) converts simple alkenes into C─N bonds under mild, near‐neutral conditions. A shared Co─H‐initiated radical/organocobalt intermediate is channeled into radical trapping, radical‐polar crossover, or radical ligand transfer, unifying hydroamination, hydroazidation, hydroamidation, and remote
Arman Khosravi, Ming‐Yu Ngai
wiley   +2 more sources

Heterocycles. CI. Syntheses and Isomerizations of Some Allylthio Nitrogen Heterocycles [PDF]

, 1973
Allylthio nitrogen heterocycles were isomerized under the influence of base into the corresponding propenylthio analogs. Subsequently, isomerization of the resultant cis-propenylthio compounds afforded the trans-isomers.
Stanovnik, B., Kočevar, M., Tišler, M.
core   +1 more source

Polycyclic Nitrogen Heterocycles [PDF]

Nature, 1953
Heterocyclic Compounds Edited by Robert C. Elderfield. Vol. 3: Polycyclic Derivatives of Pyrrole; Polycyclic Systems with One Nitrogen Common to Both Rings; Pyrindine and related Compounds. Pp. vii + 442. 96s. net. Vol. 4: Quinoline, Isoquinoline and their Benzo Derivatives. Pp. vii + 674. 136s. net.
openaire   +1 more source

Generalizable Strategies for the Synthesis of Cereblon‐Recruiting PROTAC Prodrugs

Angewandte Chemie, EarlyView.
Cereblon‐recruiting PROTACs remain challenging to derivatize for prodrug‐based delivery. In this study, three complementary conjugation strategies enabled the efficient synthesis of cleavable PROTAC prodrugs with tunable release kinetics that can be incorporated into a library of PEGylated constructs and bottlebrush prodrugs.
Aiden X. Wang, Bin Liu, Elise M. Ackerman, Yichen Xiang, Hung V.‐T. Nguyen, Yivan Jiang, Angela N. Koehler, Jeremiah A. Johnson   +7 more
wiley   +2 more sources

Catalytic asymmetric synthesis of a nitrogen heterocycle through stereocontrolled direct photoreaction from electronically excited state

Nature Communications, 2017
Despite intensive research on photoexcited molecules, stereocontrol of direct bond formation upon photoexcitation remains limited. Here the authors expand the research on stereocontrolled bond forming photochemistry and introduce the catalytic asymmetric
Xiaoqiang Huang, Xinyao Li, Xiulan Xie, Klaus Harms, Radostan Riedel, Eric Meggers   +5 more
doaj   +1 more source

Accessing Biologically Important Imines and Nitrogen Heterocycles Using an Organocatalyst

, 2022
Nitrogen-containing heterocycles play a prominent role in a variety of biological systems and drug-like molecules. Imines play an important role in the formation of these heterocycles and commercially available starting materials include alcohols and ...
Lewis, Stephonda G.
core  

Isothiazologuanosine (tzG) as Environmentally Sensitive Fluorescent Reporter in RNA

Angewandte Chemie, EarlyView.
The emissive isothiazologuanosine analog tzG is synthesized for the first time as RNA phosphoramidite building block for solid‐phase synthesis. Due to its isomorphic and isofunctional characteristics, tzG forms Watson–Crick base pairs and can be used as fluorescent probe to monitor (deoxy)ribozyme activity.
Julia Dietzsch, Yitzhak Tor, Claudia Höbartner   +2 more
wiley   +2 more sources