Results 101 to 110 of about 1,403,091 (264)

Diastereoselective Alkylation of Activated Nitrogen Heterocycles with Alkenyl Boronate Complexes. [PDF]

Angew Chem Int Ed Engl, 2023
McGettigan JE, Ready JM.
europepmc   +1 more source

Kinetically Stable Boron‐Heteroatom Bonds

Angewandte Chemie, EarlyView.
This study investigates the kinetic stability of boron‐heteroatom bonds in N‐methyliminodiacetic acid (MIDA) boronates. The hemilabile nature of the ligand enables the synthesis of molecules that would otherwise be considered too hydrolytically labile. Depending on the structure, acid‐promoted migration of the boryl group was found to produce compounds
Alina Trofimova, Ben Zhen Huang, Harjeet S. Soor, Brandon White, Aleksandra Holownia, Yury Lebedev, Alan J. Lough, Travis Dudding, Andrei K. Yudin   +8 more
wiley   +2 more sources

Alcohols as Alkylating Agents in the Cation-Induced Formation of Nitrogen Heterocycles. [PDF]

Angew Chem Int Ed Engl, 2022
Cox L, Zhu Y, Smith PJ, Christensen KE, Sidera Portela M, Donohoe TJ.   +5 more
europepmc   +1 more source

Flavin Catalysts in Organic Synthesis

Angewandte Chemie, EarlyView.
Flavins and their congeners are potent catalysts for organic synthesis inspired by enzymatic transformations. In addition to catalysis in the flavin ground state via covalent intermediates, the excited singlet and triplet states unlock applications including photooxidation, photoreduction, and energy transfer via sensitization.
Jan Freudenberg, Golo Storch
wiley   +2 more sources

Formal pyridine meta-azidation and its application for the synthesis of diazepines, ring-fused δ-carbolines and 1,2,3-triazolylpyridines

Nature Communications
The nitrogen atom serves as an important structural element in pharmacologic studies, highlighting the critical role of nitrogen-containing heterocycles in drug discovery.
Shu-Min Guo, Pengwei Xu, Constantin G. Daniliuc, Armido Studer   +3 more
doaj   +1 more source

Polar Heterobenzylic C(sp³)-H Chlorination Pathway Enabling Efficient Diversification of Aromatic Nitrogen Heterocycles. [PDF]

J Am Chem Soc, 2023
Maity S, Lopez MA, Bates DM, Lin S, Krska SW, Stahl SS.   +5 more
europepmc   +1 more source

N‐Alkoxysulfurdiimide Reagents for the One‐Step Modular Synthesis of Primary Sulfonimidamides

Angewandte Chemie, EarlyView.
N‐Alkoxysulfurdiimide reagents when combined with organometallic reagents lead directly to primary sulfonimidamide products. The reactions are broad in scope, encompassing aryl, heteroaryl, and alkyl carbon substituents. The reactivity of the N‐alkoxysulfurdiimide reagents can be correlated with the electron‐withdrawing ability of the N‐substituent ...
Suzanne E. Davison, Jonathan A. Andrews, Agamemnon E. Crumpton, Mireia Sidera Portela, Michael A. Clegg, Damien Valette, Michael C. Willis   +6 more
wiley   +2 more sources

Decoration of A-Ring of a Lupane-Type Triterpenoid with Different Oxygen and Nitrogen Heterocycles. [PDF]

Molecules, 2022
Sousa JLC, Albuquerque HMT, Silvestre AJD, Silva AMS.   +3 more
europepmc   +1 more source

An NHC‐Coordinated Silicon/Sulfur Analogue of an Acyl Carbene

Angewandte Chemie, EarlyView.
An NHC complex of an Si/S analogue of an acyl carbene is synthesized by the reaction of a disilyne with a cyclic thiourea. The observed Si2S three‐membered ring with unsymmetrical Si─S distances and a Si─Si single bond is consistent with intramolecular coordination of the silathioacyl sulfur to the silylene center.
Takuto Toyooka, Shintaro Ishida, Takeaki Iwamoto   +2 more
wiley   +2 more sources

Structural diversity using amino acid "Customizable Units": conversion of hydroxyproline (Hyp) into nitrogen heterocycles. [PDF]

Amino Acids, 2022
Hernández D, Porras M, Boto A.
europepmc   +1 more source