Results 101 to 110 of about 49,782 (284)

The Far Side of Carboranes: Anticancer Active Monocations and Ambiently Stable Dications

Angewandte Chemie, EarlyView.
This work describes the synthesis of bench‐stable dicationic carboranes. Their enhanced electrophilicity is documented by opening the clusters with weak nucleophiles or dihydrogen. The surprising stability of positively charged carboranes in water enabled a study of their in vitro antiproliferative activity, which surpassed the effects of doxorubicin ...
Vlastimil Němec, Josef Holub, Maksim A. Samsonov, Zdeňka Růžičková, Josef Cvačka, Ján Vančo, Zdeněk Trávníček, Jan Belza, Zdeněk Dvořák, Jan Vrána, Aleš Růžička   +10 more
wiley   +2 more sources

Engineering Trace‐Amount Electrolyte Additives for Aqueous Zinc Batteries

Advanced Energy Materials, EarlyView.
Large‐amount additives primarily modify the bulk electrolyte by coordinating with Zn2+ or reshaping the hydrogen‐bond network, thereby altering the overall solution chemistry. In contrast, trace‐amount additives mainly operate at the electrode–electrolyte interface, regulating Zn deposition through electric double‐layer modulation, interfacial ...
Zhaoxin Li, Jinhua Guo, Longjun Chang, Zhenyu Jiang, Shuchang Liu, Chao Wang, Qi Liu, Baohua Li, Zhiqiang Niu, Qing Li   +9 more
wiley   +1 more source

A Free N‐Heterocyclic Carbene and Its Metal Complex

Angewandte Chemie, EarlyView.
Free N‐heterocyclic carbenes (NHCs) are directly visualized on ultrathin sodium‐chloride films on gold (NaCl/Au(111)) using scanning tunneling microscopy (STM), atomic force microscopy (AFM), and density functional theory (DFT). Submolecular imaging reveals their structure and frontier orbital.
Ankita Das, Tzu‐Chao Hung, Andreas Rank, Felix Giselbrecht, Jonas Schön, Mowpriya Das, Nikos Doltsinis, Saeed Amirjalayer, Jascha Repp, Frank Glorius   +9 more
wiley   +2 more sources

A Second-Generation Janus Scorpionate Ligand: Controlling Coordination Modes in Iron(II) Complexes by Steric Modulation [PDF]

, 2008
The second-generation Janus scorpionate ligand [HB(mtdaMe)3−] containing methyl-mercaptothiadiazolyl (mtdaMe) heterocyclic rings and (N,N,N-) and (S,S,S-) binding pockets has been prepared. The effect of methyl substitution versus the unsubstituted first-
Gardinier, James R., Grandjean, Fernande, Gwengo, Chengeto, Lindeman, Sergey V., Long, Gary J., Silva, Rosalice M., Smith, Mark D.   +6 more
core   +1 more source

Biocatalytic Synthesis of Isoxazolines Enabled by Cryptic Nitrile Oxide Formation by a Vanadium‐Dependent Chloroperoxidase

Angewandte Chemie, EarlyView.
The vanadium‐dependent haloperoxidase (VHPO) class of enzymes has been shown to catalyze cryptic nitrile oxide generation in an oxidative [3+2] cycloaddition reaction between aldoximes and alkenes to generate isoxazolines. This biotechnology has been applied to a chemoenzymatic sequence starting from aldehydes through in situ condensation with ...
Manik Sharma, Kyle F. Biegasiewicz
wiley   +2 more sources

Electrochemical Generation of Nitrogen‐centered Radicals and its Application for the Green Synthesis of Heterocycles

ChemElectroChem
Electrochemistry became a unique and powerful tool for the preparation of a plethora of valuable chemical species including functional materials, drug candidates and clinically approved pharmaceuticals.
Kseniia Titenkova, Daniil A. Chaplygin, Leonid L. Fershtat   +2 more
doaj   +1 more source

Catalytic asymmetric synthesis of a nitrogen heterocycle through stereocontrolled direct photoreaction from electronically excited state

Nature Communications, 2017
Despite intensive research on photoexcited molecules, stereocontrol of direct bond formation upon photoexcitation remains limited. Here the authors expand the research on stereocontrolled bond forming photochemistry and introduce the catalytic asymmetric
Xiaoqiang Huang, Xinyao Li, Xiulan Xie, Klaus Harms, Radostan Riedel, Eric Meggers   +5 more
doaj   +1 more source

Navigating Nitration Chemistry: A Practical Guide to Reagents, Mechanisms, and Selectivity

Angewandte Chemie, EarlyView.
This review highlights key contributions of modern nitration chemistry, emphasizing sustainable mechanistic platforms and comparing the performance of both organic and inorganic reagents across aromatic, ipso‐, olefin, alkyne, and heteroatom nitration. It provides the community with a clearer, unified perspective on current advances and facilitates the
Harry Lecomte, Anthony J. Fernandes, Dmitry Katayev   +2 more
wiley   +2 more sources

Depolymerization and Reuse of Polycarbonates: Emerging Classes, Mechanisms and Challenges

Angewandte Chemie, EarlyView.
This review collects the latest developments in the area of chemical and catalytic polycarbonate recycling strategies and includes the controlled degradation of similar types of macromolecules. Apart from the main strategies for deconstruction, the key mechanistic features of these depolymerization processes are also discussed together with the ...
Davide Rigo, David H. Lamparelli, Antonio Buonerba, Carmine Capacchione, Arjan W. Kleij   +4 more
wiley   +2 more sources

Synthesis and Characterization of π‐Extended Azulenes via Nucleophilic Substitution and Intramolecular Cyclization of 5‐Alkynyl‐6‐Fluoroazulenes

ChemistryEurope
Herein, a methodology that allows a nucleophilic aromatic substitution followed by an intramolecular cyclization to furnish annulated heterocycles at the seven‐membered ring of alkynyl fluoroazulenes is introduced.
Martin C. Dietl, Matthias Scherr, Christopher Hüßler, Henrik T. Habeck, Carmen L. M. Henel, Jürgen Graf, Frank Rominger, Matthias Rudolph, A. Stephen K. Hashmi   +8 more
doaj   +1 more source