Results 111 to 120 of about 871,548 (248)

Investigating the preparation of oxime derivatives of azacrown ethers containing piperidine-4-one heterocycles under microwave irradiation

Vietnam Journal of Science, Technology and Engineering
The use of multi-component reactions to simultaneously synthesise crown ethers and nitrogen-containing heterocycles is a synthetic approach that has attracted significant interest. With nitrogen heterocycles embedded in their structures, azacrown ethers
Tung H. To, Hieu D. Nguyen
doaj   +1 more source

Remote Desaturation of Unprotected Amines and C─H Amination of Alkanes by Polarity‐Matched N‐Radical Cations

Angewandte Chemie, EarlyView.
Highly electrophilic N‐radical cations enable efficient and selective H‐atom transfer (HAT) of unprotected amines. In this exceedingly practical strategy, simple CuCl catalyzes an interrupted Hofmann–Löffler–Freytag (HLF) reaction to afford δ desaturated amines, aza‐heterocycles, and C─H aminated alkanes without protecting groups.
Pavitra Laohapaisan, Ross M. Dare, Meredith L. Rudich, Jacob J. A. Garwood, Siyuan Gong, R. Thomas Simons, David A. Nagib   +6 more
wiley   +2 more sources

Radiation-driven Destruction of N-heterocycles in the Presence and Absence of Water Ice

The Astrophysical Journal
Simple N -heterocycles are expected to be an abundant class of molecules within the interstellar medium, and increasingly complex heterocycles (e.g., nucleobases) have been detected within meteoritic organic material and in samples returned from the ...
Patrick D. Tribbett, Yukiko Y. Yarnall, Perry A. Gerakines, Reggie L. Hudson, Christopher K. Materese   +4 more
doaj   +1 more source

Chemical Switching Between B2N and B2C Homoaromaticity

Angewandte Chemie, EarlyView.
We report the synthesis of homoaromatic 1‐aza‐2,4‐diazadiboretane with a bicyclic four‐membered NB2C motif and demonstrate experimentally and theoretically that the homoaromatic delocalization can also be chemically shifted from the B2N to the B2C moiety by deprotonation of the ring carbon atom.
Tim Wiesmeier, Philipp Grewelinger, Carsten Präsang, Bernd Morgenstern, Diego M. Andrada, David Scheschkewitz   +5 more
wiley   +2 more sources

Diastereoselective Alkylation of Activated Nitrogen Heterocycles with Alkenyl Boronate Complexes. [PDF]

Angew Chem Int Ed Engl, 2023
McGettigan JE, Ready JM.
europepmc   +1 more source

High‐Tg Polythioesters From Isomerization Ring‐Opening Polymerization of a Renewable Oxanorbornane‐Fused Thionolactone

Angewandte Chemie, EarlyView.
A biobased tricyclic thionolactone undergoes selective isomerization ring‐opening polymerization to yield a high‐molecular‐weight polythioester with an exceptionally high Tg of 171°C, exceeding that of the analogous polyester. The polythioester efficiently depolymerizes through backbiting, while its hydrolysis and methanolysis reveal the critical ...
Eva Harsevoort, Henk‐Jan Akkerman, Martin Lutz, Arnaud Thevenon, Pieter C. A. Bruijnincx   +4 more
wiley   +2 more sources

Formal pyridine meta-azidation and its application for the synthesis of diazepines, ring-fused δ-carbolines and 1,2,3-triazolylpyridines

Nature Communications
The nitrogen atom serves as an important structural element in pharmacologic studies, highlighting the critical role of nitrogen-containing heterocycles in drug discovery.
Shu-Min Guo, Pengwei Xu, Constantin G. Daniliuc, Armido Studer   +3 more
doaj   +1 more source

Alcohols as Alkylating Agents in the Cation-Induced Formation of Nitrogen Heterocycles. [PDF]

Angew Chem Int Ed Engl, 2022
Cox L, Zhu Y, Smith PJ, Christensen KE, Sidera Portela M, Donohoe TJ.   +5 more
europepmc   +1 more source

Síntese de derivados heterocíclicos com potencial atividade antitripanossomatídeos [PDF]

, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2014.Os fármacos utilizados nos tratamentos atuais de tripanossomatídeos, Trypanosoma cruzi (doença de ...
Zimmermann, Lara Almida
core  

Intramolecular Nickel‐Catalyzed Reductive Coupling: Enantioselective Synthesis of Tetrahydroisoquinolines and Related Heterocycles

Angewandte Chemie, EarlyView.
The successful extension of the nickel‐catalyzed asymmetric coupling of polarized 1,3‐dienes with aldehydes to an intramolecular setting opens an efficient new entry into hydroxylated N‐heterocyclic compounds, most notably valuable tetrahydroisoquinolines.
Thilo Bender, Markus Leutzsch, Yannik Sell, Alois Fürstner   +3 more
wiley   +2 more sources