Results 121 to 130 of about 10,807 (177)
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Phosphorus-nitrogen compounds. 24. Phosphoramide mustard carrier derivatives
Journal of Medicinal Chemistry, 1984Diethylstilbestrol, psoralen, and propranolol were used as potential carrier molecules for selective concentrations of a nitrogen mustard moiety in breast, skin, and lung tissues, respectively. The propranolol derivative gave two racemic mixtures, which were tested to ascertain any differences in anticancer activity.
L A, Cates +3 more
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The influence of some sulfur-containing compounds on the toxicity of nitrogen mustards
Toxicology and Applied Pharmacology, 1963Abstract Measurements of the effect of nitrogen mustards on the cholinesterase activity of the small intestine of rats indicated that HN1 and HN2 cause a decrease in enzyme activity of the intestine that is maximal at 2–4 days after administration and is reversible after sublethal doses of the nitrogen mustards.
B E, HIETBRINK, A B, RAYMUND
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Carbohydrates and nitrogenous compounds in the honeydew of the mustard aphid, Lipaphis erysimi
Journal of Insect Physiology, 1970Abstract The chemical composition of the leaf sap of the radish, a host plant for the mustard aphid, Lipaphis erysimi , is compared with the composition of the honeydew that is excreted. The results indicate that the aphid utilizes sugars in a descending order of glucose, pentose sugars, fructose, and dextrins.
Harcharn Singh Sidhu, R.L. Patton
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Journal of Pharmaceutical Sciences, 1961
The rates of formation of ethyleneimonium ion resulting only from the initial cyclization of a β-chloroethyl group of various nitrogen mustard compounds are reported. A polarographic technique was used for the quantitative determination of the ethyleneimonium ions.
H, ZALLEN, J E, CHRISTIAN, A M, KNEVEL
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The rates of formation of ethyleneimonium ion resulting only from the initial cyclization of a β-chloroethyl group of various nitrogen mustard compounds are reported. A polarographic technique was used for the quantitative determination of the ethyleneimonium ions.
H, ZALLEN, J E, CHRISTIAN, A M, KNEVEL
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A chlorine-35 nuclear quadrupole resonance study of some nitrogen mustard compounds
Journal of Magnetic Resonance (1969), 1977Abstract A linear relationship has been established between the 35Cl nuclear quadrupole resonance frequency and the sum of the Hammet δ parameters for several aromatic nitrogen mustard compounds. This relationship is given by f q =1.024 ∑ i=1 n where fq is the quadrupole resonance frequency in megahertz, δ1 is the Hammett δ ...
David W Sheppard, Philip J Bray
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Biochemical Pharmacology, 1960
Abstract The azo-mustard 4-di-2″-chloroethylaminoazobenzene-2′-carboxylic acid was found to be mutagenic in Drosophila melanogaster males. The mutagenic effect was found only in pre-meiotic germ cell stages and, of these, late spermatids were the most sensitive. Sterility or egg unhatchability was found to be due to aspermia.
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Abstract The azo-mustard 4-di-2″-chloroethylaminoazobenzene-2′-carboxylic acid was found to be mutagenic in Drosophila melanogaster males. The mutagenic effect was found only in pre-meiotic germ cell stages and, of these, late spermatids were the most sensitive. Sterility or egg unhatchability was found to be due to aspermia.
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ChemInform Abstract: PHOSPHORUS‐NITROGEN COMPOUNDS. 24. PHOSPHORAMIDE MUSTARD CARRIER DERIVATIVES
Chemischer Informationsdienst, 1984AbstractDargestellt und auf Antitumor‐Aktivität untersucht werden die Verbindungen (I)‐(III).
L. A. CATES +3 more
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The Synthesis Of Nitrogen Mustard Derivatives Of Some Steroids And Related Compounds.
1951PhD ; Chemistry ; University of Michigan, Horace H. Rackham School of Graduate Studies ; http://deepblue.lib.umich.edu/bitstream/2027.42/179112/2/0003761 ...
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Cancer, 1958
Nitrogen mustard and radiogold in combination markedly inhibit growth of the intraperitoneal ascitic form of the Ehrlich ascites carcinoma in mice. The best inhibiting dose of radiogold, 15 mc/kg, was the most toxic one; 7.5 mc/kg was found to be the most effective dose with the least toxicity.
R W, WHITEHEAD +2 more
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Nitrogen mustard and radiogold in combination markedly inhibit growth of the intraperitoneal ascitic form of the Ehrlich ascites carcinoma in mice. The best inhibiting dose of radiogold, 15 mc/kg, was the most toxic one; 7.5 mc/kg was found to be the most effective dose with the least toxicity.
R W, WHITEHEAD +2 more
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Acta Radiologica, 1958
Investigations into the protective action of cyeteamine against nitrogen mustard (HN2) are described. A selective protection upon the bone marrow as compared with the small intestine and spleen was observed. The comparative protective action of related agents is discussed in detail and an explanation is put forward for the variation in the toxicity of ...
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Investigations into the protective action of cyeteamine against nitrogen mustard (HN2) are described. A selective protection upon the bone marrow as compared with the small intestine and spleen was observed. The comparative protective action of related agents is discussed in detail and an explanation is put forward for the variation in the toxicity of ...
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