Results 161 to 170 of about 30,885 (243)
New compounds: N-arylglyoxylohydroxamyl derivatives of nitrogen mustard
The synthesis and physical properties of some N,N - bis (2 - chloroethyl)arylglyoxylohy-droxamamides are described.
J P, Larocca, C A, Gibson
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The influence of some sulfur-containing compounds on the toxicity of nitrogen mustards
Abstract Measurements of the effect of nitrogen mustards on the cholinesterase activity of the small intestine of rats indicated that HN1 and HN2 cause a decrease in enzyme activity of the intestine that is maximal at 2–4 days after administration and is reversible after sublethal doses of the nitrogen mustards.
B E, HIETBRINK, A B, RAYMUND
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A chlorine-35 nuclear quadrupole resonance study of some nitrogen mustard compounds
Abstract A linear relationship has been established between the 35Cl nuclear quadrupole resonance frequency and the sum of the Hammet δ parameters for several aromatic nitrogen mustard compounds. This relationship is given by f q =1.024 ∑ i=1 n where fq is the quadrupole resonance frequency in megahertz, δ1 is the Hammett δ ...
David W Sheppard, Philip J Bray
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A comparison of the effects of various nitrogen mustard compounds on embryonic cells
D, BODENSTEIN, A, GOLDIN
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Mutagenicity of heterocyclic nitrogen mustards (ICR compounds) in cultured mammalian cells.
The mutagenicity of six heterocylic nitrogen mustards (ICR compounds) has been determined in a cultured mammalian cell system by use of resistance to the purine analog 6-thioguanine to select for mutation induction at the hypoxanthine-guanine phosphoribosyltransferase locus in Chinese hamster ovary cells. The six compounds tested are ICR 191, 170, 292,
J P, O'Neill, J C, Fuscoe, A W, Hsie
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Comparative Therapeutic Activity of the Nitrogen Mustards and Allied Compounds
M P, SYKES +2 more
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THE TOXICITY AND PHARMACOLOGICAL ACTION OF THE NITROGEN MUSTARDS AND CERTAIN RELATED COMPOUNDS
WILLIAM P. ANSLOW +3 more
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Phosphorus-nitrogen compounds. 24. Phosphoramide mustard carrier derivatives
Journal of Medicinal Chemistry, 1984Diethylstilbestrol, psoralen, and propranolol were used as potential carrier molecules for selective concentrations of a nitrogen mustard moiety in breast, skin, and lung tissues, respectively. The propranolol derivative gave two racemic mixtures, which were tested to ascertain any differences in anticancer activity.
L A, Cates +3 more
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