Results 81 to 90 of about 117,489 (150)
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A TECHNIQUE FOR INTRAPLEURAL ADMINISTRATION OF NITROGEN MUSTARD COMPOUNDS
The American Journal of the Medical Sciences, 1957L. Taylor
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A comparison of the effects of various nitrogen mustard compounds on embryonic cells
Journal of Experimental Zoology, 1948Abraham Goldin, Dietrich Bodenstein
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CHEMICAL REACTIONS OF THE NITROGEN MUSTARD GASES.1 VI. THE REACTIONS OF THE NITROGEN MUSTARD GASES WITH CHEMICAL COMPOUNDS OF BIOLOGICAL INTEREST [PDF]
The Journal of Organic Chemistry, 1946 JOSEPH S. FRUTON +3 more
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Bioorganic & Medicinal Chemistry Letters, 1997
Abstract A prodrug consisting of a β-D-glucuronic acid linked to a self-immolative spacer (a N-( ortho -hydroxyphenyl)-N-methylcarbamate) and a phenolic nitrogen mustard was synthesised. As this prodrug was easily cleaved by a β-glucuronidase enzyme and displayed low cytotoxicity, it must be considered as appropriate for an ADEPT approach.
Jean Claude Florent +6 more
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Abstract A prodrug consisting of a β-D-glucuronic acid linked to a self-immolative spacer (a N-( ortho -hydroxyphenyl)-N-methylcarbamate) and a phenolic nitrogen mustard was synthesised. As this prodrug was easily cleaved by a β-glucuronidase enzyme and displayed low cytotoxicity, it must be considered as appropriate for an ADEPT approach.
Jean Claude Florent +6 more
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Analytical Chemistry, 2022
Some mustard compounds (mustards) are highly toxic chemical warfare agents. Some are explored as new anticancer drugs. Therefore, the fast, selective, and sensitive detection of mustards is extremely important for public security and cancer therapy ...
Xiangui Ma +6 more
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Some mustard compounds (mustards) are highly toxic chemical warfare agents. Some are explored as new anticancer drugs. Therefore, the fast, selective, and sensitive detection of mustards is extremely important for public security and cancer therapy ...
Xiangui Ma +6 more
semanticscholar +1 more source
460. Cytotoxic compounds. Part II. Some amides of the “nitrogen mustard” type
J. Chem. Soc., 1961L. N. Owen +3 more
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New compounds: N-arylglyoxylohydroxamyl derivatives of nitrogen mustard
Journal of Pharmaceutical Sciences, 1967The synthesis and physical properties of some N,N - bis (2 - chloroethyl)arylglyoxylohy-droxamamides are described.
Joseph P. Larocca, C.A. Gibson
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Archiv der Pharmazie, 2020
A new series of N‐substituted pyrazoline derivatives 6a–g, 7a–g, 8a–g, and 9a–g was synthetized by reaction of hydrazine derivatives and chalcone–thiazole hybrids bearing nitrogen mustard 5a–g.
Viviana Cuartas +11 more
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A new series of N‐substituted pyrazoline derivatives 6a–g, 7a–g, 8a–g, and 9a–g was synthetized by reaction of hydrazine derivatives and chalcone–thiazole hybrids bearing nitrogen mustard 5a–g.
Viviana Cuartas +11 more
semanticscholar +1 more source
The influence of some sulfur-containing compounds on the toxicity of nitrogen mustards
Toxicology and Applied Pharmacology, 1963Abstract Measurements of the effect of nitrogen mustards on the cholinesterase activity of the small intestine of rats indicated that HN1 and HN2 cause a decrease in enzyme activity of the intestine that is maximal at 2–4 days after administration and is reversible after sublethal doses of the nitrogen mustards.
Hietbrink Be, Raymund Ab
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Phosphorus-nitrogen compounds. 24. Phosphoramide mustard carrier derivatives
Journal of Medicinal Chemistry, 1984AbstractDargestellt und auf Antitumor‐Aktivität untersucht werden die Verbindungen (I)‐(III).
van der Helm D +3 more
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