Results 1 to 10 of about 8,282 (214)
Nitazoxanide and tizoxanide demonstrate high levels of in vitro activity against metronidazole-susceptible and metronidazole-resistant Trichomonas vaginalis clinical isolates [PDF]
Microbiology SpectrumTrichomonas vaginalis is the most common non-viral sexually transmitted infection worldwide. We compared the in vitro activity of the thiazolide nitazoxanide (NTZ) and its metabolite, tizoxanide (TIZ), with the activity of the Food and Drug ...
Keonte J. Graves +5 more
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Journal of Pharmacy and Bioallied SciencesBackground: Periodontitis is a slow progressing infection and has profound systemic implications. The influence of various therapeutic drugs to inhibit inflammation and promote bone regeneration has been studied.
Prabhu Manickam Natarajan
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Determination of Residues of 5-Nitroimidazoles and Their Metabolites in Eggs by Isotope Dilution-Ultra-high Performance Liquid Chromatography-Tandem Mass Spectrometry [PDF]
Shipin Kexue, 2023 A rapid method was developed and validated for the simultaneous identification and quantitation of the residues of 5-nitroimidazoles and their metabolites in eggs by isotope dilution-ultra-high performance liquid chromatography-tandem mass spectrometry ...
QIU Xiaoyi, WANG Dongmei, LI Jiakuan, XU Qing, WANG Mengying, GUAN Zhuolong, LU Yuepeng, TU Fengqin
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Design and synthesis of 4-nitroimidazole derivatives with potential antitubercular activity
Тонкие химические технологии, 2023 Objectives. To develop the procedures for synthesis of hybrid molecules with potential anti-tubercular activity containing heterocyclic cores of 4-nitroimidazole and 1,3,4-thiadiazole within the framework of a double-drug strategy and predict bioactivity
T. S. Vedekhina +2 more
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Designing molecular diagnostics for current tuberculosis drug regimens
Emerging Microbes and Infections, 2023 Diagnostic development must occur in parallel with drug development to ensure the longevity of new treatment compounds. Despite an increasing number of novel and repurposed anti-tuberculosis compounds and regimens, there remains a large number of drugs ...
Sophia B. Georghiou +9 more
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Biomédica: revista del Instituto Nacional de Salud, 2020 Introducción. Trypanosoma cruzi, agente causal de la enfermedad de Chagas, exhibe una sustancial heterogeneidad fenotípica y genotípica que puede influir en las variaciones epidemiológicas y clínicas de la enfermedad, así como en la sensibilidad a los ...
Nidia Acosta +6 more
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Compounds, 2023 The discovery of azomycin provided the major impulse for the systematic search for medicines showing activity against anaerobic protozoa. Nowadays, many other interesting applications have been found for nitroimidazoles as therapeutic agents.
Justyna Żwawiak, Lucjusz Zaprutko
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In Vitro Effect of 5-Nitroimidazole Drugs against Trichomonas vaginalis Clinical Isolates
Microbiology Spectrum, 2022 Infections with the sexually transmitted parasite Trichomonas vaginalis are normally treated with metronidazole, but cure rates are suboptimal and recurrence rates following treatment are high.
Andile Mtshali +5 more
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Clinical and Neuroradiological Spectrum of Metronidazole Induced Encephalopathy: Our Experience and the Review of Literature [PDF]
Journal of Clinical and Diagnostic Research, 2016 Metronidazole is an antimicrobial agent mainly used in the treatment of several protozoal and anaerobic infections, additionally, is often used in hepatic encephalopathy and Crohn disease.
Ujjawal Roy +4 more
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Pharmaceuticals, 2021 Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), is a curable airborne disease currently treated using a drug regimen consisting of four drugs.
Klaudia T. Angula +2 more
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