Results 61 to 70 of about 5,742 (217)

Confirmatory Analysis of Nitroimidazoles and Hydroxy Metabolites in Honey by Dispersive-Solid Phase Extraction and Ultra-High Performance Liquid Chromatography-Tandem Mass Spectrometry

Molecules, 2018
An ultra-high performance liquid chromatography-tandem quadrupole mass spectrometry (UHPLC-MS/MS) method was developed and validated for confirmatory analysis of four nitroimidazoles and three hydroxy metabolites in honey. Honey samples were dissolved in
Xiaowei Li, Yuebin Ke, Yingyu Wang, Chengfei Wang, Dongyang Ye, Xue Hu, Lan Zhou, Xi Xia   +7 more
doaj   +1 more source

The Broad Ecological Range of Salmonella enterica Serotype Typhimurium Is Associated With Genomic Diversification

Environmental Microbiology, Volume 28, Issue 11, November 2026.
The broad ecological range of Salmonella enterica serotype Typhimurium is associated with dynamic gain and loss of accessory genes, including plasmid‐associated antimicrobial resistance (AMR) genes, along with positive selection on core genes, potentially contributing to its differential adaptation across food animal and non‐food animal reservoirs ...
Leela Ohri, Sandeep Chinnareddy, Ying‐Xian Goh, Hailong Zhang, Xiangyu Deng, Amy Pruden, Rachel Cheng, Song Li, Jingqiu Liao   +8 more
wiley   +1 more source

Binding constants of inclusion complexes of nitroimidazoles with β-cyclodextrins in the absence and presence of PVP

, 2007
Thermodynamics of complexation of 5-nitroimidazoles with β -cyclodextrin and its methylated and hydroxypropyl derivatives in water and in 0.25% polyvinylpyrrolidone are determined by solution calorimetry. A 1:1 stoichiometry was established.
Thakur, Deepika, Chadha, Renu, Jain, D. V. S., Singh, Surjit, Aggarwal, Amit   +4 more
core   +1 more source

Antimicrobial Resistance in Periodontal Disease: Rethinking Adjunctive Therapy in the Metagenomics Era, the Pressing Need for Precision Treatment and Periodontal Resistome Mapping

Journal of Cellular and Molecular Medicine, Volume 30, Issue 21, November 2026.
ABSTRACT Systemic antibiotics are effective when used as adjunctive therapy in the treatment of periodontitis; however, their use must be balanced against antimicrobial resistance, which is a major threat to global public health. This review provides an expert synthesis of the literature and a field‐level overview of antimicrobial resistance in ...
Meera Alghafri, Lindsey Edwards, David Moyes, Luigi Nibali   +3 more
wiley   +1 more source

Nitroimidazoles. Part XXIII. Activity of satranidazole series against anaerobic infections

, 1992
A large number of nitroimidazoles have been examined for in vitro activity against three anaerobes - Bacteroides fragilis (Bf), a strain of Bf resistant to metronidazole (16a) and Clostridium perfringens and many found to be active.
George, T., Nair, M. D., Shenoy, S. J., Gowrishankar, R., Arya, V. P., Sudarsanam, V., Nagarajan, K.   +6 more
core   +1 more source

ESTUDIO EXPERIMENTAL Y TEÓRICO DE LA SÍNTESIS DE N-ALQUIL-NITROIMIDAZOLES EXPERIMENTAL AND THEORETICAL STUDY OF SHYNTESIS OF N-ALKYL-NITROIMIDAZOLES.

Vitae, 2010
En este trabajo se realizó un estudio experimental y teórico sobre la N-alquilación de nitroimidazoles. Los N-alquil-2-metil-nitroimidazoles corresponden a moléculas con actividad biológica, que se obtienen por la reacción del 2-metil-5-nitroimidazol y ...
Constain SALAMANCA M, William TIZNADO V, Paula JARAMILLO G   +2 more
doaj  

Acid‐Stable Nitrofuran Triple Therapy With Rabeprazole and Amoxicillin Targeting Helicobacter pylori Infection

MedComm, Volume 7, Issue 10, October 2026.
Overview: Novel nitrofuran derivatives were developed and evaluated against Helicobacter pylori to overcome antibiotic resistance and inflammation. Methods and Findings: In vitro assays using H. pylori 60190 and PMSS1 strains demonstrated potent antibacterial activity, reduced bacterial adhesion, and inhibited cytokine release from gastric epithelial ...
Nagendran Tharmalingam, Kulandaisamy Arulsamy, Shaolei Lu, Sadhna Dhingra, Scott Goodrich, Joseph St Laurent, Gerald Jones, Eleftherios Mylonakis   +7 more
wiley   +1 more source

Nitroimidazoles: Molecular fireworks that combat a broad spectrum of infectious diseases

, 2017
Infectious diseases claim millions of lives every year, but with the advent of drug resistance, therapeutic options to treat infections are inadequate. There is now an urgent need to develop new and effective treatments.
Mark A. T. Blaskovich, Ang, Chee Wei, Blaskovich, Mark A. T., Jarrad, Angie M., Angie M. Jarrad, Matthew A. Cooper, Cooper, Matthew A., Chee Wei Ang   +7 more
core   +1 more source

Collisionally induced loss of NO2 radical loss from protonated nitroimidazoles and nitropyrazoles [PDF]

, 2002
peer reviewedThe collisionally induced loss of NO2 of protonated nitroimidazoles and nitropyrazoles was investigated for the possible generation of hydrogen shift isomers of imidazole and pyrazole radical cations. Ab initio calculations at B3LYP/6-31+G(d,
Elguero, José, Gerbaux, Pascal, Flammang, Robert, Le, Hung Thanh, Nguyen, Minh Tho   +4 more
core   +1 more source

Empirical Meropenem Versus Piperacillin/Tazobactam for Critically Ill Adults With Sepsis: Feasibility of a Randomised Trial

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 9, October 2026.
ABSTRACT Background Meropenem and piperacillin/tazobactam are commonly used empirical antibiotics in critically ill adults with sepsis, but whether one is superior to the other is uncertain. Methods The Empirical Meropenem versus Piperacillin/Tazobactam for Adult Patients with Sepsis (EMPRESS) trial is an ongoing investigator‐initiated, randomised ...
Nick Frørup Meier, Morten Hylander Møller, Maj‐Brit Nørregaard Kjær, Fredrik Sjövall, Marie Warrer Munch, Benjamin Skov Kaas‐Hansen, Hans‐Christian Thorsen‐Meyer, Bodil Steen Rasmussen, Marie Helleberg, Frederik Boëtius Hertz, Theis Lange, Aksel Karl Georg Jensen, Lars Wiuff Andersen, Jakob Steen Andersen, Jens Michelsen, Lars Peter Kloster Andersen, Morten Heiberg Bestle, Anne Craveiro Brøchner, Theis Skovsgaard Itenov, Steffen Christensen, Ronni Thermann Reitz Plovsing, Klaus Ulrik Koch, Anders Møller, Olav Lilleholt Schjørring, Naia Bech Cranø, Kasper Vamdrup‐Andersen, Davide Placido, Tine Sylvest Meyhoff, Carl Thomas Anthon, Aske Tøgern, Milda Grigonyte‐Daraskeviciene, Zemira Engbakken, Anne Witte Kamstrup, Kis Rønn Uhre, Jehad Ahmad Barakji, Rikke Faebo Larsen, Anders Perner, Anders Granholm   +37 more
wiley   +1 more source