Results 81 to 90 of about 8,282 (214)

NanoPET imaging of [18F]fluoromisonidazole uptake in experimental mouse tumours [PDF]

open access: yes, 2018
Purpose: The purpose of this study was to assess the potential and utility of ultra-high-resolution hypoxia imaging in various murine tumour models using the established hypoxia PET tracer [18F]fluoromisonidazole ([18F]FMISO).
Ametamey, Simon   +3 more
core  

Activity Profiling of Nitro‐Substituted Di(Hetero)Aryl 1,3,4‐ and 1,2,4‐Oxadiazoles: Antimicrobial, Cholinesterase Inhibition and Antioxidant Potential

open access: yesArchiv der Pharmazie, Volume 359, Issue 1, January 2026.
Novel nitro‐substituted diaryl 1,3,4‐ and 1,2,4‐oxadiazoles were synthesised via molecular hybridisation of bioactive heterocycles. Selected derivatives exhibited potent antimicrobial activity, including against Mycobacterium tuberculosis and Staphylococcus aureus, and cholinesterase inhibitory activity, with promising selectivity.
Enikő Šikorová   +9 more
wiley   +1 more source

Using 5-Nitroimidazole Derivatives against Neglected Tropical Protozoan Diseases: Systematic Review

open access: yesFuture Pharmacology
Neglected tropical diseases (NTDs) are a significant global health problem. Additionally, anti-protozoan treatments are toxic, and their therapeutic regimens require prolonged treatment times and high concentrations of the drugs.
Micheel M. Vichi-Ramírez   +3 more
doaj   +1 more source

Adsorptive removal of antibiotics from water and wastewater: Progress and challenges [PDF]

open access: yes, 2015
© 2015 Elsevier B.V. Antibiotics as emerging contaminants are of global concern due to the development of antibiotic resistant genes potentially causing superbugs. Current wastewater treatment technology cannot sufficiently remove antibiotics from sewage,
Ahmed, MB, Guo, W, Ngo, HH, Zhou, JL
core   +1 more source

The Impact of Chlamydia Treatment During Pregnancy on Birth Defects in New York State

open access: yesBirth Defects Research, Volume 118, Issue 1, January 2026.
ABSTRACT Background Chlamydia trachomatis (CT) diagnoses are highest among females of reproductive age. Yet, little is known about adverse infant outcomes associated with treatment for CT infections during pregnancy, including birth defects. Methods Using de‐identified matched data from the New York State (NYS) Sexually Transmitted Infection ...
Elizabeth M. Boos   +6 more
wiley   +1 more source

ESTUDIO EXPERIMENTAL Y TEÓRICO DE LA SÍNTESIS DE N-ALQUIL-NITROIMIDAZOLES EXPERIMENTAL AND THEORETICAL STUDY OF SHYNTESIS OF N-ALKYL-NITROIMIDAZOLES.

open access: yesVitae, 2010
En este trabajo se realizó un estudio experimental y teórico sobre la N-alquilación de nitroimidazoles. Los N-alquil-2-metil-nitroimidazoles corresponden a moléculas con actividad biológica, que se obtienen por la reacción del 2-metil-5-nitroimidazol y ...
Constain SALAMANCA M   +2 more
doaj  

Nitroimidazoles XIII. Synthesis of Substituted (1-Methyl-5-Nitro-2-Imidazolyl) Isoxazoles [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 1998
The beta0diketone derivatives of nitroimidazole were synthesized from the reaction of magnesium salt of beta-ketoaccids 3 with imidazolide 4. The raction of beta-diketones with hydroxylamine hydrochloride afforded either the isoxazoles or the 5-hydroxyl ...
Abbas Shafiee, Mohammad ALi Ebrahimzadeh
doaj  

The Certification of the Mass Fraction of Chloramphenicol in Pork Meat - Certified Reference Material ERM®-BB130 [PDF]

open access: yes, 2010
This report describes the preparation of the pork meat matrix reference material ERM-BB130 and the certification of the content (mass fraction) of chloramphenicol. The preparation and processing of the material, homogeneity and stability studies, and the
EMONS Hendrik   +3 more
core   +1 more source

In vitro and in vivo pharmacodynamics of three novel antileishmanial lead series

open access: yesInternational Journal for Parasitology: Drugs and Drug Resistance, 2018
Objectives: Three new chemical series (bicyclic nitroimidazoles, aminopyrazoles and oxaboroles) were selected by Drugs for Neglected Diseases initiative as potential new drug leads for leishmaniasis. Pharmacodynamics studies included both in vitro and in
M. Van den Kerkhof   +7 more
doaj   +1 more source

NITROIMIDAZOLES VIII [I]. SYNTHESES, ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES OF 2-PYRIDYL-NITROIMIDAZOLES [PDF]

open access: yesJournal of Sciences, Islamic Republic of Iran, 1990
Starting from 2-(2-pyridyl) imidazole a series of substituted imidazoles (2-5) were prepared. From the reaction of 2-(3-pyridyl) -4-(or 5) nitroimidazole (15) with dimethyl sulfate in alkaline medium 1-methyl-2-(3- pyridy1)-4-nitroimidazole (6,)w as ...
doaj  

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