Results 21 to 30 of about 7,972 (156)
Molecules, 2021 Herein, we report the neuroprotective and antioxidant activity of 1,1′-biphenyl nitrones (BPNs) 1–5 as α-phenyl-N-tert-butylnitrone analogues prepared from commercially available [1,1′-biphenyl]-4-carbaldehyde and [1,1′-biphenyl]-4,4′-dicarbaldehyde. The
Beatriz Chamorro +8 more
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Tikrit Journal of Pure Science, 2023 This study investigated the condensation reactions between N-(3,4-dimethoxybenzyl)hydroxylamine and N-(4-methylbenzyl)hydroxylamine with glyoxalic acid. The objective was to obtain imine derivatives as the desired target products.
Jihad Haji Mohammed +3 more
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Unnatural Amino Acid and Emerging Chemistry Approaches to Map RNA–Protein Interactions
Angewandte Chemie, EarlyView.This review highlights emerging chemistries for mapping RNA–protein interactions, including genetically encoded unnatural amino acids, novel photocrosslinkers, and non‐photoactivatable crosslinking systems. We compare their mechanisms, reactivity and applications, outlining how these next‐generation tools enable higher‐resolution, site‐specific ...
Eryn Lundrigan +3 more
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Synthesis and Antioxidant Properties of Novel 1,2,3-Triazole-Containing Nitrones
Antioxidants, 2022 Herein, we report the synthesis and antioxidant capacity of twelve novel 1,2,3-triazole-containing nitrones such as N-(2-(4-aryl-1H-1,2,3-triazol-1-yl)ethylidene)methanamine oxides 8a–f and N-(2-(4-aryl)-1H-1,2,3-triazol-1-yl)ethylidene)-2-methylpropan-2-
Dimitra Hadjipavlou-Litina +3 more
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Scientific Reports, 2023 Cerebral ischemia is a condition affecting an increasing number of people worldwide, and the main cause of disability. Current research focuses on the search for neuroprotective drugs for its treatment, based on the molecular targets involved in the ...
Beatriz Chamorro +8 more
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Crystal structure of C-2-benzothiazole-N-methylnitrone
Acta Crystallographica Section E: Crystallographic Communications, 2015 The molecule of the title compound {systematic name: N-[(benzothiazol-2-yl)methylidene]methylamine N-oxide}, C9H8N2OS, is close to planar [maximum deviation from the mean plane = 0.081 (2) Å], its conformation being stabilized by a strong intramolecular ...
Roman Doroschuk
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Crystal structure of (Z)-N-benzylidene-1-phenylmethanamine oxide hydrogen peroxide monosolvate
Acta Crystallographica Section E: Crystallographic Communications, 2017 The title adduct, C14H13NO·H2O2, consists of (Z)-N-benzylidene-1-phenylmethanamine oxide and hydrogen peroxide molecules in a 1:1 ratio. The organic coformer adopts a skew geometry with an inter-aryl-ring dihedral angle of 81.9 (2)°.
Andrei V. Churakov +3 more
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Synthesis and Glycosidase Inhibition of Broussonetine M and Its Analogues
Molecules, 2019 Cross-metathesis (CM) and Keck asymmetric allylation, which allows access to defined stereochemistry of a remote side chain hydroxyl group, are the key steps in a versatile synthesis of broussonetine M (3) from the d-arabinose-derived cyclic nitrone 14 ...
Qing-Kun Wu +6 more
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Frontiers in Immunology, 2018 Recent studies suggest both beneficial and detrimental role of increased reactive oxygen species and oxidative stress in heart failure (HF). However, it is not clear at which stage oxidative stress and oxidative modifications occur in the endothelium in ...
Bartosz Proniewski +6 more
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Journal of Pharmacological Sciences, 2008 Scavenging activity of α-phenyl-N-tert-butyl nitrone (PBN) against singlet oxygen (1O2) and its effects on 1O2-induced neuronal cell death were examined. PBN at 1–4mM dose-dependently suppressed 1O2 released from activated human neutrophils.
Anna Kawai +8 more
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