Results 31 to 40 of about 7,868 (205)

Amidinoquinoxaline-Based Nitrones as Lipophilic Antioxidants [PDF]

Antioxidants, 2021
The potential of nitrones (N-oxides) as therapeutic antioxidants is due to their ability to counteract oxidative stress, mainly attributed to their action as radical scavengers toward C- and O-centered radicals. Among them, nitrones from the amidinoquinoxaline series resulted in interesting derivatives, due to the ease with which it is possible to ...
Nadia Gruber, Liliana Orelli, Cristina Minnelli, Luca Mangano, Emiliano Laudadio, Giovanna Mobbili, Pierluigi Stipa   +6 more
openaire   +5 more sources

Immuno-Spin Trapping-Based Detection of Oxidative Modifications in Cardiomyocytes and Coronary Endothelium in the Progression of Heart Failure in Tgαq*44 Mice

Frontiers in Immunology, 2018
Recent studies suggest both beneficial and detrimental role of increased reactive oxygen species and oxidative stress in heart failure (HF). However, it is not clear at which stage oxidative stress and oxidative modifications occur in the endothelium in ...
Bartosz Proniewski, Joanna Czarny, Tamara I. Khomich, Kamil Kus, Agnieszka Zakrzewska, Stefan Chlopicki, Stefan Chlopicki   +6 more
doaj   +1 more source

Synthesis and Glycosidase Inhibition of Broussonetine M and Its Analogues

Molecules, 2019
Cross-metathesis (CM) and Keck asymmetric allylation, which allows access to defined stereochemistry of a remote side chain hydroxyl group, are the key steps in a versatile synthesis of broussonetine M (3) from the d-arabinose-derived cyclic nitrone 14 ...
Qing-Kun Wu, Kyoko Kinami, Atsushi Kato, Yi-Xian Li, Yue-Mei Jia, George W. J. Fleet, Chu-Yi Yu   +6 more
doaj   +1 more source

A mechanistic investigation of the oxidation of N,α-diphenylnitrones by dichloramine-T in aqueous acetonitrile medium - a non-linear Hammett plot [PDF]

Journal of the Serbian Chemical Society, 2009
The kinetics of oxidation of a number of meta- and para-substituted N,α-diphenylnitrones (nitrone) by dichloramine-T (DCT) was investigated in the presence of alkali in aqueous acetonitrile medium.
Manivarman S., Rajarajan G., Manikandan G., Sekar M., Jayabharathi J., Thanikachalam V.   +5 more
doaj   +1 more source

Crystal structure of trans-dichloridobis[N-(5,5-dimethyl-4,5-dihydro-3H-pyrrol-2-yl-κN)acetamide]palladium(II) dihydrate

Acta Crystallographica Section E: Crystallographic Communications, 2017
The title complex, [PdCl2(C8H14N2O)2]·2H2O, was obtained by N–O bond cleavage of the oxadiazoline rings of the trans-[dichlorido-bis(2,5,5-trimethyl-5,6,7,7a-tetrahydropyrrolo[1,2-b][1,2,4]oxadiazole-N1)]palladium(II) complex.
Jamal Lasri, Naser Eltaher Eltayeb, Matti Haukka, Bandar A. Babgi   +3 more
doaj   +1 more source

Cooperative Photocatalysis of 9,10‐Phenanthrenequinone and Sn(OTf)2 for Direct Mannich Reaction of Ethers via Hydrogen Atom Transfer Pathway

Advanced Synthesis &Catalysis, EarlyView.
A dual photocatalytic system of o‐PQ and Sn(OTf)2 enables visible light‐induced Mannich‐type addition of ethers to nitrones via Csp³–H activation. This oxidant‐free method offers broad scope and good yields. Mechanistic studies suggest that a photoexcited o‐PQ–Sn(II) complex mediates hydrogen atom transfer to form α‐oxy radicals for nitrone addition. A
Pradip Ramdas Thorve, Hun Young Kim, Kyungsoo Oh   +2 more
wiley   +1 more source

Recent Advances in Ene Reactions with Carbon Enophiles

Advanced Synthesis &Catalysis, EarlyView.
Recent advances in the classical intra‐ and intermolecular ene nexus with carbon enophiles (alkenes, alkynes, arynes, and allenes) show a considerable increase in structural complexity and an enormous potential for functional applications in polymer science.
Thomas J. J. Müller
wiley   +1 more source

α-Phenyl-N-tert-butyl Nitrone Has Scavenging Activity Against Singlet Oxygen (1O2) and Attenuates 1O2-Induced Neuronal Cell Death

Journal of Pharmacological Sciences, 2008
Scavenging activity of α-phenyl-N-tert-butyl nitrone (PBN) against singlet oxygen (1O2) and its effects on 1O2-induced neuronal cell death were examined. PBN at 1–4mM dose-dependently suppressed 1O2 released from activated human neutrophils.
Anna Kawai, Yoko Nishinaka, Toshiyuki Arai, Kiichi Hirota, Hiroko Mori, Nobuyuki Endo, Takashi Miyoshi, Kouhei Yamashita, Masataka Sasada   +8 more
doaj   +1 more source

From Molecule to Meaning: Click and Bioorthogonal Chemical Reporters for Plant Systems, Biological Imaging, and Artistic Expression

ChemBioChem, EarlyView.
At the intersection of chemical biology, plant imaging, and contemporary art, this review introduces the concept of chembioart. By tracing how chemical reporters illuminate plant biomolecules in vivo, their role not only in advancing scientific understanding but also in inspiring transdisciplinary collaborations and visual expression is highlighted ...
Marie Hinnebo, Clémence Simon, Adèle Tilouine, Corentin Spriet, Christophe Biot   +4 more
wiley   +1 more source

Biocompatible Chemistry: A Plug‐and‐Play Toolbox for Chemical Biology Research

ChemBioChem, EarlyView.
The “plug‐and‐play” nature of biocompatible chemistry makes it a powerful toolbox for investigating complicated biological systems and producing drug leads for clinical usages. This review summarizes the commonly used biocompatible reactions and the recent advances of their representative applications in chemical biology research, thus highlighting the
Adam R. Lovato, Zeng Lin, Qingfei Zheng
wiley   +1 more source