Results 41 to 50 of about 7,868 (205)

Nephroprotective Effects of Tetramethylpyrazine Nitrone TBN in Diabetic Kidney Disease

Frontiers in Pharmacology, 2021
Diabetic kidney disease (DKD) is the leading cause of end-stage renal failure, but therapeutic options for nephroprotection are limited. Oxidative stress plays a key role in the pathogenesis of DKD.
Mei Jing, Mei Jing, Yun Cen, Fangfang Gao, Ting Wang, Jinxin Jiang, Qianqian Jian, Liangmiao Wu, Liangmiao Wu, Baojian Guo, Fangcheng Luo, Fangcheng Luo, Gaoxiao Zhang, Ying Wang, Lipeng Xu, Zaijun Zhang, Yewei Sun, Yuqiang Wang   +17 more
doaj   +1 more source

Nitrones as Versatile Linkages for the Construction of Covalent Organic Polymers by Tandem Transformations

ChemistryEurope, EarlyView.
The nitrone moiety's versatility in covalent organic polymer (COP) materials is shown by its ability to form either nitrone‐linked or oxime O‐ether‐linked COPs from the same building blocks, simply by changing reaction conditions. Additionally, its 1,3‐dipolar cycloaddition reactivity enabled the synthesis of a functionalized isoxazolidine‐linked ...
Beatriz de Santos, M. José Capitán, Jesús Álvarez, Isabel Sobrados, Silvia Cabrera, Alberto Fraile, José Alemán   +6 more
wiley   +1 more source

Cycloaddition and Annulation Reactions with Donor‐Acceptor Cyclobutanes

Helvetica Chimica Acta, EarlyView.
Reviewing the rise of donor‐acceptor cyclobutanes in (4 + 2) annulations, from Lewis/Brønsted acid to electrocatalysis, enabling stereoselective access to complex heterocycles and natural products. Abstract Donor‐acceptor (DA) cyclobutanes are emerging as valuable synthetic intermediates due to their ring strain and polarized C─C bonds, which allow for
Emma G. L. Robert, Jerome Waser
wiley   +1 more source

Chemiexcitation in Ex Vivo Porcine Skin Model

Pigment Cell &Melanoma Research, Volume 38, Issue 6, November 2025.
Formation of triplet excited carbonyl by direct chemiexcitation in the fibroblasts of the dermis and in the melanocytes and keratinocytes of the epidermis in the porcine skin, followed by excitation energy transfer from triplet excited carbonyl to melanin via radiative and non‐radiative pathways by indirect chemiexcitation.
Pavel Pospíšil, Vendula Paculová, Ankush Prasad, Michal Berecka   +3 more
wiley   +1 more source

Copper-mediated synthesis of N-alkenyl-α,β-unsaturated nitrones and their conversion to tri- and tetrasubstituted pyridines

Beilstein Journal of Organic Chemistry, 2015
A Chan–Lam reaction has been used to prepare N-alkenyl-α,β-unsaturated nitrones, which undergo a subsequent thermal rearrangement to the corresponding tri- and tetrasubstituted pyridines.
Dimitra Kontokosta, Daniel S. Mueller, Dong-Liang Mo, Wiktoria H. Pace, Rachel A. Simpson, Laura L. Anderson   +5 more
doaj   +1 more source

Alpha, Beta- Unsaturated Lactone-Nitrone Cycloadditions: a Route to the Synthesis of (±)–Tussilagin [PDF]

مجلة جامعة النجاح للأبحاث العلوم الطبيعية, 1994
Reaction of nitrone (V with a, f1 -unsaturated lactone C.4) resulted in the isolation of a single adduct (7). The observed high regiochemical control has encouraged further explorations of natural product synthesis.
Mohammed A. Al-Nuri
doaj   +1 more source

Synthesis of Cyclic Sulfilimines and Sulfoximines via Copper‐Mediated C(sp2)–H Sulfanylation of Benzylamines with a Catalytic Transient Directing Group

ChemistryEurope, Volume 3, Issue 5, September 18, 2025.
Copper‐mediated transient C─H sulfanylation of benzylamines with sulfenamides enables rapid access to thioethers, cyclic sulfilimines, and sulfoximines. Mechanistic investigations using 1H NMR and electron paramagnetic resonance spectroscopy reveal an unprecedented thermally induced homolytic cleavage of the sulfenamide N─S bond, slowly releasing the ...
Tsz‐Kan Ma, Peerawat Saejong, King‐Long Or, Callum S. Begg, James A. Bull   +4 more
wiley   +1 more source

Boron–Boron Single Bonds Mimicking Transition Metals

European Journal of Inorganic Chemistry, Volume 28, Issue 23, August 26, 2025.
Through careful design of the substituents, ambiphilic cationic diboranes are formed through substituent elimination from stable nucleophilic diboranes. The ambiphilic reactivity could be used to coordinate and selectively reduce organic substrates in the diborane coordination sphere.
Hans‐Jörg Himmel
wiley   +1 more source

A Brief History of Plastic Additives. Part 1: Antioxidants

Macromolecular Materials and Engineering, Volume 310, Issue 8, August 2025.
The development of suitable antioxidants has been a decisive element for the success of plastics in particular in the field of polyolefins. Sterically hindered phenol structures, amines, and sulfur‐containing products including multifunctional substances comprise today´s commercial range. Stabilizers based on renewable resources and tailor‐made systems
Rudolf Pfaendner
wiley   +1 more source

SYNTHESES AND ANTIFUNGAL ACTIVITY OF 3-ARYLMETHYL-5-ARYLOXY METHYL-2- METHY LISOXAZOLIDINES [PDF]

Journal of Sciences, Islamic Republic of Iran, 1998
Reaction of sodium salt of allyl alcohol with 2-chloro-5-phenyl- l,3,4-thiadiazole gave 2-allyloxy-5-phenyl-1,3,4-thiadiazole 2. Compounds 4a and 4b could be obtained through the reaction of nitrone 3 with 2.
doaj