Direct Amination of Nitroquinoline Derivatives via Nucleophilic Displacement of Aromatic Hydrogen [PDF]
Molecules, 2021 The vicarious nucleophilic substitution of hydrogen (VNS) reaction in electron-deficient nitroquinolines was studied. Properties of all new products have been characterized by several techniques: MS, HRMS, FTIR, GC-MS, electronic absorption spectroscopy,
Jakub Wantulok +6 more
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In Vitro Selective Combinatory Effect of Ciprofloxacin with Nitroxoline, Sanguinarine, and Zinc Pyrithione against Diarrhea-Causing and Gut Beneficial Bacteria [PDF]
Microbiology Spectrum, 2022 Antibiotic resistance in diarrhea-causing bacteria and its disruption of gut microbiota composition are health problems worldwide. The development of combinatory agents that increase the selective inhibitory effect (synergism) against diarrheagenic ...
Hayford Osei-Owusu +6 more
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Reduction of 4-Nitroquinoline 1-Oxide by Microörganisms
Chemical and Pharmaceutical Bulletin, 1962 The ultraviolet absorption maximum of 4-nitroquinoline 1-oxide was shifted toward shorter wave length when the substance was added to the growing media of microorganisms. The investigation of this phenomenon revealed that the shift in ultraviolet absorption maxima is due to the reduction of nitro group at 4-position. It was also foundthat the reduction
Tadashi Okabayashi, Akihiro Yoshimoto
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Acta Crystallographica Section E Structure Reports Online, 2011 The molecule of the title compound, C(9)H(6)N(2)O(2), is almost planar, with a dihedral angle of 3.0 (9)° between the pyridine and benzene rings.
Liang Xu +4 more
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Reduction of 8-nitroquinolines [PDF]
Australian Journal of Chemistry, 1970 Ainscough E.W., Plowman R.A.
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Microwave-assisted synthesis of a MK2 inhibitor by Suzuki-Miyaura coupling for study in Werner syndrome cells [PDF]
, 2015 Microwave-assisted Suzuki-Miyaura cross-coupling reactions have been employed towards the synthesis of three different MAPKAPK2 (MK2) inhibitors to study accelerated aging in Werner syndrome (WS) cells, including the cross-coupling of a 2-chloroquinoline
Bagley, Mark C +5 more
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8-Hydroxy-5-nitroquinoline as a C-nucleophilic reagent in the reaction of C, C-coupling with quinazoline [PDF]
, 2020 The first example of the reaction of 5-nitro-8-hydroxyquinoline as a C-nucleophile with quinazoline is described. As a result of the reaction of C, C-coupling, a stable σ-adduct containing the drug nitroxalin on a heterocyclic carrier was obtained.
Azev, Yuri A. +4 more
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Identification and Characterization of Bioactive Components in Datura stramonium Leaves: an insight into Drugs Discovery [PDF]
, 2022 Medicines from plants help in treating ailments, but to utilize them effectively in the management of diseases requires the identification of potent phytochemicals relative to conventional drugs. These phytochemicals are compared with synthetics drugs in
Jones, B.B. +5 more
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Asymmetric Intramolecular Conjugate Addition Nitro-Mannich Route to cis-2-Aryl-3-nitrotetrahydroquinolines [PDF]
, 2015 Reductive cyclization of 2-iminonitrostyrenes (from the condensation of 2-aminostyrenes with an aldehyde and subsequent nitration of the alkene) using a bifunctional thiourea catalyst and tert-butyl-Hantzsch ester leads to an intramolecular conjugate ...
Anderson, JC, Barham, JP, Rundell, CD
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A first example of cobalt-catalyzed remote C-H functionalization of 8-aminoquinolines operating through a single electron transfer mechanism [PDF]
, 2016 The development of new C[BOND]H functionalization protocols based on inexpensive cobalt catalysts is currently attracting significant interest. Functionalized 8-aminoquinoline compounds are high-potential building blocks in organic chemistry and ...
Ackermann +49 more
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