Results 31 to 40 of about 364 (179)

Spectrophotomatic Assay for the Enzyme Catalyzed Reaction of 4-nitroquinoline 1-oxide with Glutathione [PDF]

, 1987
4-Nitroquinoline 1-oxide (4NQO(is a toxic and carcinogenic compound that has been reported to be subject to conjugation with glutathione (GSH). This reaction may proceed non-enzymatically or be catalyzed by GSH transferases.
Benson, Ann M., Stanley, J. Steven
core   +1 more source

The Use of Silver Rotating Disk Electrode to Suppress Passivation During Voltammetric Determination of 4-Nitrophenol [PDF]

, 2023
In this bachelor's thesis results of the optimization of the measurement of 4-nitrophenol (1·10-4 mol·l-1 ) in the Britton-Robinson (BR) buffer medium on the silver rotating disk electrode are presented with the aim of suppressing the passivation of the ...
Pitřinec, Jakub
core  

Oral Acute Toxicity and Genotoxicity of Heteroctenus junceus Scorpion Venom

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
The Heteroctenus junceus scorpion venom is a very popular natural extract used in traditional medicine in Cuba. In clinically relevant experimental settings, scorpion venom does not induce general toxicity or an increase in the frequency of micronucleus formation in erythrocytes.
Alexis Díaz‐García, Jenny Laura Ruiz‐Fuentes, Sophia Mejias Medina, Nicolas Zapata Guajardo, Christian Ross Skarneo   +4 more
wiley   +1 more source

Insufficient Expression of the Autophagic Protein ATG16L1 Results in Accelerated Carcinogenesis Related to an Aberrant B Cell Response

Cancer Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background Autophagy‐related proteins (ATGs) regulate a great variety of cellular responses beyond autophagy. In cancer, the role of ATG proteins is central, as evidenced in spontaneous cancer emerging in animals lacking ATG proteins. Aim To determine whether ATG16L1 may be participating in tumorigenesis in colonic and oral mucosa and its ...
Daniela Mendiola, Betsaida Ortiz, Oscar Nieto, Marisol I. González, Danielle Vannan, Bertus Eksteen, Alejandro Martínez, Diego Mateos, Mónica G. Mendoza‐Rodríguez, Miriam Rodríguez‐Sosa, Luis I. Terrazas, José L. Reyes   +11 more
wiley   +1 more source

Optimized Lanthanide(III) Tags for Rapid and Efficient Protein Labeling in Electron Paramagnetic Resonance and Luminescence Applications

ChemistryEurope, Volume 4, Issue 1, January 2026.
Three novel Ln(III) complexes for efficient, site‐specific cysteine labeling under mild aqueous conditions are reported. A kinetic study reveals how subtle changes to the reactive pendant arm tune tagging rates, with Tb.QuNO achieving >95% cysteine labeling in 10 min.
Lydia Topping, Elena M. Mocanu, S. Ronan Fisher, Robert I. Hunter, Yasmin Ben‐Ishay, Daniella Goldfarb, Graham M. Smith, Janet E. Lovett, Stephen J. Butler   +8 more
wiley   +1 more source

The In Vitro Transgenic Rodent Assay in Primary MutaMouse Hepatocytes Compared to the Mammalian Cell Gene Mutation Assay Using the HPRT Gene

Environmental and Molecular Mutagenesis, Volume 67, Issue 1-2, January‐February 2026.
ABSTRACT Gene mutations can be detected in mammalian cells in vitro using indicator genes such as the hypoxanthine‐guanine‐phosphoribosyltransferase (HPRT) gene. These assays have been adopted as OECD test guidelines (TG, e.g., OECD TG no. 476) and are used for regulatory purposes.
Alina Göpfert, Kylee Kendra Marie Ronnenberg, Claudia Ruelker, Silke Spang, Naveed Honarvar, Robert Landsiedel   +5 more
wiley   +1 more source

7-Donor-, 8-Akzeptor-substituierte Chinoline als ESIPT-Photoschalter [PDF]

, 2019
Im Rahmen dieser Arbeit wurden substituierte Chinoline mit einem Wasserstoffdonor in Position 7 und einem Wasserstoffakzeptor in Position 8 synthetisiert, um ESIPT-switch-fähige Moleküle zu erhalten.
Rönn, Jesper
core  

Toxicological Assessment of LN20188, a Botanical Combination of Withania somnifera Root and Abelmoschus esculentus Fruit Extracts

BioMed Research International, Volume 2026, Issue 1, 2026.
LN20188 is a botanical combination composed of extracts derived from Withania somnifera (L.) Dunal root and Abelmoschus esculentus (L.) Moench fruit. Our earlier investigations revealed the benefits of LN20188 in promoting gut motility and reducing constipation.
Ravikumar Madireddy, Sundararaju Dodda, Gopichand Chinta, KrishnaRaju Venkata Alluri, Himangshu Himangshu   +4 more
wiley   +1 more source

Comprehensive Genotoxicity and 28‐Day Oral Toxicity Evaluation Reveal Safety of a Standardized Anisomeles indica‐Containing Powder

BioMed Research International, Volume 2026, Issue 1, 2026.
Anisomeles indica is widely used in traditional medicine and functional foods; however, its toxicological safety has not been systematically evaluated. This study evaluated the genotoxicity and subacute oral toxicity of a standardized A. indica‐containing powder (AIHP) using OECD‐compliant test guidelines.
Yng-Tay Chen, Yu-Ru Chen, Fuu-Jen Tsai, Ter-Hsin Chen, Yoel A. Klug   +4 more
wiley   +1 more source

Screening and Mechanism Study of Antibacterial Activity of Quinoline Compounds

Journal of Chemistry, Volume 2026, Issue 1, 2026.
Quinoline compounds possess a wide range of pharmacological activities. In this paper, the antibacterial activity of 59 quinoline derivatives was evaluated against three plant bacteria in vitro. Among all the derivatives, 8‐hydroxyquinoline (8HQ) demonstrated significant antibacterial activity against Rs, Aac, Xoc, Xoo, Xac, Xcm, Xcc, Psa, and Xf, with
Haonan Sun, Zhiyuan Xu, Yan Xu, Jing Wang, Fadi Zhu, Huochun Ye, Yongxia Guo, Gang Feng, Jing Zhang, Sohini Basu Roy   +9 more
wiley   +1 more source