Reduction of 4-Nitroquinoline 1-Oxide by Microörganisms
Chemical and Pharmaceutical Bulletin, 1962 The ultraviolet absorption maximum of 4-nitroquinoline 1-oxide was shifted toward shorter wave length when the substance was added to the growing media of microorganisms. The investigation of this phenomenon revealed that the shift in ultraviolet absorption maxima is due to the reduction of nitro group at 4-position. It was also foundthat the reduction
Tadashi Okabayashi, Akihiro Yoshimoto
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Successful Treatment of Balamuthia mandrillaris Granulomatous Amebic Encephalitis with Nitroxoline. [PDF]
Emerg Infect Dis, 2023 Spottiswoode N +17 more
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Hypoxia-selective antitumor prodrugs and fluorescent probes [PDF]
Hypoxia-selective antitumor prodrugs utilize the unique feature of most tumors -- hypoxia (low oxygen concentration), for therapeutic purpose and are widely studied in preclinical and clinical stages. Tirapazamine (TPZ, 3-amino-1,2,4-benzotriazine-1,4-di-
Shen, Xiulong
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Intramolecular conjugate addition nitro-mannich reaction: Towards the synthesis of schizozygine [PDF]
, 2016 Part 1: The introduction of this thesis describes in detail the development of the nitro-Mannich reaction, in particular organocatalytic methodologies and its use in the synthesis of N-heterocycles.
Rundell, CD
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Rationally repurposed nitroxoline inhibits preclinical models of Epstein-Barr virus-associated lymphoproliferation. [PDF]
J Antibiot (Tokyo), 2021 Ibáñez de Garayo M +4 more
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Target Based Design And Synthesis of Heterocycles in the Potential Treatment of Cancer and Opportunistic Infection [PDF]
, 2017 Dose limiting toxicity and development of multidrug resistance by the tumors are the major limitations of current cancer chemotherapy. Microtubule targeting agents (MTAs) are a structurally diverse set of compounds that disrupt microtubule dynamics and ...
Choudhary, Shruti
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Molecular Basis of 4‐Nitroquinoline 1‐Oxide Carcinogenesis [PDF]
Japanese Journal of Cancer Research, 1989 Bailleul, Bernard +3 more
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SNH Amidation of 5-Nitroisoquinoline: Access to Nitro- and Nitroso Derivatives of Amides and Ureas on the Basis of Isoquinoline. [PDF]
Molecules, 2022 Avakyan EK +6 more
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Carcinogen 4-Nitroquinoline Oxide (4-NQO) Induces Oncostatin-M (OSM) in Esophageal Cells. [PDF]
In Vivo, 2023 Mukherjee A +8 more
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