Results 31 to 40 of about 1,746 (206)

The Use of Silver Rotating Disk Electrode to Suppress Passivation During Voltammetric Determination of 4-Nitrophenol [PDF]

, 2023
In this bachelor's thesis results of the optimization of the measurement of 4-nitrophenol (1·10-4 mol·l-1 ) in the Britton-Robinson (BR) buffer medium on the silver rotating disk electrode are presented with the aim of suppressing the passivation of the ...
Pitřinec, Jakub
core  

Sex‐Related Differences in Histone Acetylation and Tumor Development in a 4‐Nitroquinoline 1‐Oxide and Ethanol‐Induced Oral Squamous Cell Carcinoma Mouse Model

Journal of Oral Pathology &Medicine, Volume 54, Issue 10, Page 1074-1084, November 2025.
ABSTRACT Background Oral squamous cell carcinoma (OSCC) is one of the most frequent head and neck cancers. The 4‐nitroquinoline 1‐oxide (4NQO) mouse model of oral carcinogenesis is a well‐established model to investigate the mechanism behind OSCC development, including epigenetic alterations.
Wender Rodrigues Nazário, Anaíra Ribeiro Guedes Fonseca Costa, Débora de Oliveira Santos, Nayara Rúbio Diniz Del Nero, Tamiris Sabrina Rodrigues, Luiza Diniz Ferreira Borges, Carlos Ueira‐Vieira, Sérgio Vitorino Cardoso, Adriano Mota Loyola, Paulo Rogério de Faria   +9 more
wiley   +1 more source

Spectrophotomatic Assay for the Enzyme Catalyzed Reaction of 4-nitroquinoline 1-oxide with Glutathione [PDF]

, 1987
4-Nitroquinoline 1-oxide (4NQO(is a toxic and carcinogenic compound that has been reported to be subject to conjugation with glutathione (GSH). This reaction may proceed non-enzymatically or be catalyzed by GSH transferases.
Benson, Ann M., Stanley, J. Steven
core   +1 more source

STIP1 drives Metabolic Reprogramming in Esophageal Squamous Cell Carcinoma via AHCY‐LDHA Axis

Exploration, Volume 5, Issue 5, October 2025.
A schematic model illustrating that LCA can inhibit ESCC growth by inhibiting the STIP1/AHCY/LDHA axis. In brief. Jin et al. demonstrated that targeting STIP1 can significantly inhibit the progression of esophageal squamous cell carcinoma. The high expression of STIP1 increased the interaction between AHCY and LDHA and then AHCY recruits PRMT3 to ...
Guoguo Jin, Yanming Song, Mingyang Yan, Shaobo Fang, Yang Shao, Kexin Zhao, Meng Liu, Qinxin Guo, Xinyang Jia, Chengjuan Zhang, Zhenwei Wang, Kangdong Liu, Xiang Li, Simin Zhao, Mee‐Hyun Lee, Zhiping Guo, Zigang Dong   +16 more
wiley   +1 more source

Reply to the opinion paper “The impact of stress on rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide: some theoretical concepts for scientific debate” by Silva et al. [PDF]

, 2022
Giseli Mitsuy Kayahara, Flávia Alves Verza, Vítor Bonetti Valente, Glauco Issamu Miyahara, Daniel Galera Bernabé   +4 more
openalex   +1 more source

Evaluation of Quercus infectoria Phytoconstituents Against Oral Cancer: Network Pharmacology, Docking Simulation, and In Vitro Cytotoxicity Assay

Food Science &Nutrition, Volume 13, Issue 9, September 2025.
This study illustrates a workflow exploring Quercus infectoria against oral cancer through network pharmacology, target prediction, molecular docking, DFT, molecular dynamics, and pathway enrichment. Molecular docking showed strong binding affinities of Nyctanthic acid and β‐Glucogallin with AKT1 and GAPDH, respectively, with the Nyctanthic acid‐AKT1 ...
Priyanka Kamaria, Priyanka Tiwari, Prabitha Prabhakaran, Sakshi Bhardwaj, Krishna Kolachi, Shankar Thapa   +5 more
wiley   +1 more source

Evaluating the Genotoxicity and Mutagenicity of Food Contaminants: Acrylamide, Penitrem A, and 3‐Acetyldeoxynivalenol in Individual and Combined Exposure In Vitro

Journal of Applied Toxicology, Volume 45, Issue 9, Page 1750-1760, September 2025.
ABSTRACT This study aimed to evaluate the genotoxic effects of food contaminants exposure in human neuroblastoma SH‐SY5Y cells using the micronucleus (MN) assay and Ames test. Acrylamide (AA), penitrem A (PEN A), and 3‐acetyldeoxynivalenol (3‐ADON) were tested both individually and in combination.
Luna Bridgeman, Cristina Juan, Houda Berrada, Isabelle Severin, Ana Juan‐García   +4 more
wiley   +1 more source

Identification of Hot and Cold Regions for Mutagenesis in the Escherichia coli tdk Gene: A Catalog of Mutational Sites

Environmental and Molecular Mutagenesis, Volume 66, Issue 6-7, Page 327-340, August 2025.
ABSTRACT We constructed a catalog of mutational sites in the tdk gene of Escherichia coli that consists of 378 different base pair substitutions at 245 different sites (base pairs). This allows us to examine the tendency of different sub‐regions of the gene to be more or less prone to mutations when compared with other sub‐regions.
Katherine Douglas, Dana Sorensen, Arnav Saud, Ananya Sridharan, Mallika Mathew, Jyotsna Hiranandani, Ava Gonick, Courtney Young, Kelly Nguyen, Nhu Phi, Jeffrey H. Miller   +10 more
wiley   +1 more source

7-Donor-, 8-Akzeptor-substituierte Chinoline als ESIPT-Photoschalter [PDF]

, 2019
Im Rahmen dieser Arbeit wurden substituierte Chinoline mit einem Wasserstoffdonor in Position 7 und einem Wasserstoffakzeptor in Position 8 synthetisiert, um ESIPT-switch-fähige Moleküle zu erhalten.
Rönn, Jesper
core  

Allergenicity, Genotoxicity and Subchronic Toxicity Assessment of IgG Binding Protein LT Produced From Aspergillus oryzae

Journal of Applied Toxicology, Volume 45, Issue 8, Page 1614-1636, August 2025.
ABSTRACT Gastrointestinal health is one of the fastest growing areas in the food and beverage industry, as its importance to overall health and well‐being is becoming increasingly recognized. Immunoglobulins play a key role in protecting the gastrointestinal tract, and nonbovine sources of immunoglobulins (including camel milk, which has a long history
Kirt R. Phipps, Sachin Patel, Kevin Scaife, Toby Holmes, Alica Šoltésová, Sandra Wingaard Thrane, Louise Kristine Vigsnæs, Nigel Baldwin, Christel Jørgensen   +8 more
wiley   +1 more source