Results 101 to 110 of about 5,837 (209)
Infection and Drug Resistance, 2021 Ying Zhang,1 Lingbo Wang,2 Cui Zhou,2 Yishuai Lin,1 Shixing Liu,2 Weiliang Zeng,1 Kaihang Yu,1 Tieli Zhou,2 Jianming Cao1 1Department of Medical Lab Science, School of Laboratory Medicine and Life Science, Wenzhou Medical University, Wenzhou, Zhejiang ...
Zhang Y +8 more
doaj
, 2001 Investigations were carried out to identify a suitable prodrug activating system for feline gene therapy with the eventual aim of treating feline thyroid disease and feline neoplasia. The E.
Reid, S.W.J. +3 more
core
Fast analysis of nitrobenzene by nitroreductase modified electrode
, 2011 Nitroreductase (NR) was modified on glass carbon electrode and used in nitrobenzene analysis. Both cyclic voltammetry (CV) and triple potential step chronocoulometry (TPSC) with a narrow potential step interval were used.
Liu, C. M. +7 more
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Flavin-Dependent Nitroreductases
ChemCatChemNitroreductases, present within both prokaryotes and eukaryotes, form a group of flavin-dependent enzymes capable of reducing nitro compounds using NAD(P)H as reducing agent. These enzymes have been widely studied due to their diverse roles in bioremediation, cancer therapy, cell ablation, and antimicrobial resistance.
Russo, Sara +3 more
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Molecular Study: Nitroreductase Enzyme and Nitroimmidazole Resistance Genes (Nim Genes) Effect on AMR to Metronidazole in Clostridium difficile [PDF]
Nitroreductase enzymes and Nim genes have been observed to be a factor predisposing to reduced susceptibility to metronidazole in anaerobic bacteria. Therefore, this study was determined the effect of nitroreductase enzymes and nim genes in metronidazole
Mohammed, Olufunmilayo, Baines, Simon
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Degradation of trinitrotoluene by transgenic nitroreductase in Arabidopsis plants
Plant, Soil and Environment, 2018 The explosive 2,4,6-trinitrotoluene (TNT) is a highly toxic and persistent environmental pollutant. TNT is toxic to many organisms, it is known to be a potential human carcinogen, and is persistent in the environment.
Bo ZHU +5 more
doaj +1 more source
Directed Evolution and Discovery of Nitroreductase Enzymes for Targeted Cell Ablation
, 2015 Nitroreductase enzymes are a superfamily of bacterial flavoproteins that can catalyze the reduction of aromatic nitro groups. The reduction of an aromatic nitro group, a highly electronegative functionality, causes a large electronic shift that can ...
Little, Rory Fox (11703950)
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, 2017 Bacterial nitroreductase enzymes, which exhibit the capacity to reduce a wide range of nitroaromatic drugs, antibiotics and environmental pollutants, have shown promise in the activation of prodrugs such as CB1954 and PR-104A.
Rich, Michelle Hedley (11816909)
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, 2016 Cyclic and acyclic nitroaryl phosphoramide mustard analogues were activated by E. coli nitroreductase, an enzyme explored in GDEPT. The more active acyclic 4-nitrobenzyl phosphoramide mustard (7) showed 167 500× selective cytotoxicity toward ...
Jiye Han (2535457) +9 more
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, 2012 Thermotoga maritima peroxiredoxin–nitroreductase hybrid enzyme (Prx–NR) consists of a FMN-containing nitroreductase (NR) domain fused to a peroxiredoxin (Prx) domain. These domains seem to function independently as no electron transfer occurs between them.
Anusevicius, Zilvinas +3 more
openaire +2 more sources