Results 101 to 110 of about 6,542 (200)

Biocatalytic Reduction of a Non-aromatic Nitro Group by a Nitroreductase from Salmonella Typhimurium

, 2014
Biocatalytic reduction of a non-aromatic nitro group by a nitroreductase from Salmonella typhimurium. A nitroreductase from Salmonella typhimurium (NRSal) was studied for its ability to reduce an aliphatic nitro ...
Reams, Thomas, Oliff, Ryan
core  

Synthesis and Evaluation of Nitroheterocyclic Aromatic Adamantanohydrazones with Trypanocidal Activity. Part III. [PDF]

ACS Infect Dis
Foscolos AS, Stavropoulou K, Santarém N, Cordeiro da Silva A, Taylor MC, Calogeropoulou T, Tsotinis A, Papanastasiou IP, Kelly JM, Wyllie S.   +9 more
europepmc   +1 more source

Cloning, purification and possible use of a Bacillus nitroreductase in biotechnological applications. [PDF]

Sci Rep
Tuşar Demir FR, Güven K, Matpan Bekler F, Gül Güven R, Küce Çevik P, Yilmaz MA, Yalaz S.   +6 more
europepmc   +1 more source

A genetic reporter for visualizing nitroreductase activity using magnetic resonance imaging. [PDF]

Chem Methods
Wan J, Chacko AN, Xu E, Kuriakose K, Mukherjee A.   +4 more
europepmc   +1 more source

5‑Nitrofuran-Semicarbazone Hybrids as Antitrypanosomal Agents: Structure-Activity Relationship and Nitroreductase Activation. [PDF]

ACS Med Chem Lett
Alegbejo Price TO, Silva DG, Vaidergorn MM, Augusto BS, Matheeussen A, Van Pelt N, Caljon G, Riley J, Read KD, Medina-Franco JL, Nonato MC, Emery FS.   +11 more
europepmc   +1 more source

Structures of Nitroreductase in Three States [PDF]

Journal of Biological Chemistry, 2002
Chad A. Haynes, Ronald L. Koder, Anne-Frances Miller, David W. Rodgers   +3 more
openaire   +1 more source

Bioresponsive pseudoGlucosinolates (psGSLs) Release Isothiocyanates (ITCs) in the Presence of Nitroreductases. [PDF]

Chemistry
Jimidar CC, Ganskow CSG, Kagho MD, Chakrabarti A, Wiese L, Zollo M, Beutling U, Cesar LC, Morud J, Bugaj K, Brönstrup M, Sieber SA, Hacker SM, Klahn P.   +13 more
europepmc   +1 more source

Biocatalytic reduction of nitro-sulfonamides: enzyme engineering, process integration, and sustainable pathways to <i>p</i>-aminobenzenesulfonamide. [PDF]

Front Bioeng Biotechnol
Ai R, Muhammad N, Cui Y, Wang L, Wang Y, Weng S, Kakar MU, Khan S, Ahmad S.   +8 more
europepmc   +1 more source

Nitroaryl Phosphoramides as Novel Prodrugs for E. coli Nitroreductase Activation in Enzyme Prodrug Therapy

, 2003
Cyclic and acyclic nitroaryl phosphoramide mustard analogues were activated by E. coli nitroreductase, an enzyme explored in GDEPT. The more active acyclic 4-nitrobenzyl phosphoramide mustard (7) showed 167 500x selective cytotoxicity toward ...
Jiang Y, Browne P, Searle PF, Li Z, Yu C, Race PR, Knox RJ, Hyde EI, Hu L, Han J   +9 more
core  

A Nitroreductase-Activatable Lapachol Against Bacillus subtilis Unveils Antimicrobial Specificity. [PDF]

ChemMedChem
Lopez-Miranda IR, Ma T, Milstein JN, Beharry AA.   +3 more
europepmc   +1 more source