Results 171 to 180 of about 26,472 (210)

Protective Role of p66Shc Deletion in Physiological Renal Aging: Effects on G Protein-Coupled Receptor 124 Expression and Associated Cellular Senescence. [PDF]

Int J Mol Sci
Iacobini C, Vitale M, Sentinelli F, Lucarelli A, Haxhi J, Sergio I, Pugliese G, Menini S.   +7 more
europepmc   +1 more source

Safflower Yellow Pigment Alleviates Cerebral Ischemia-Reperfusion Injury via Protein Nitration and Oxidative Modulation. [PDF]

Brain Behav
Wang K, Zhang X, Zhao Y, Li L, Zhao R.
europepmc   +1 more source

Therapeutic potential of L-carnitine in coronary artery disease: a systematic review. [PDF]

Inflammopharmacology
Werida RH, Okda SM.
europepmc   +1 more source

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Plasma 3-Nitrotyrosine in Cigarette Smokers

American Journal of Respiratory and Critical Care Medicine, 1997
Peroxynitrite has been associated with increased oxidative reactions and DNA damage in inflamed tissues as it may cause a reduction of plasma antioxidants as well. Nitration of tyrosine residues of proteins leads to the production of 3-nitrotyrosine (NTYR), which may be considered as a marker of NO.-dependent oxidative damage.
PETRUZZELLI S, PUNTONI R, MIMOTTI P, PULERA N, BALIVA F, FORNAI E, GIUNTINI, CARLO   +6 more
openaire   +3 more sources

Nitrotyrosine in Otitis Media with Effusion

Annals of Otology, Rhinology & Laryngology, 2005
Objectives: Our purpose was to investigate mucosal cell injury due to the nitric oxide (NO)-superoxide system in otitis media with effusion. Methods: We determined the levels of nitrotyrosine (NT) and NO and the activities of superoxide dismutase (SOD) and lactic dehydrogenase (LDH) in 90 middle ear fluid samples.
Ken-ichi, Hisamatsu, Hajime, Inoue, Kiyoshi, Makiyama, Masami, Homma   +3 more
openaire   +2 more sources

3-Nitrotyrosine in Atherosclerotic Blood Vessels

Clinical Chemistry and Laboratory Medicine, 2003
The effect of peroxynitrite on the development of atherosclerosis is one of the major foci of recent studies. Here, the cytotoxic effect of peroxynitrite was investigated by quantitatively measuring nitrated tyrosine, 3-nitrotyrosine (3-NT) levels in atherosclerotic blood vessels.
Nehir, Sucu, Ali, Unlü, Lülüfer, Tamer, Barlas, Aytacoglu, Bahadir, Ercan, Murat, Dikmengil, Ugur, Atik   +6 more
openaire   +2 more sources

Do Human Atherosclerotic Lesions Contain Nitrotyrosine?

Biochemical and Biophysical Research Communications, 1996
Nitrotyrosine has been widely used as a marker of peroxynitrite formation in normal and diseased tissues. However, studies of normal human aortic intima and atherosclerotic lesions at various stages of development failed to reveal its presence except in a very few specimens of both normal and diseased tissues.
P, Evans, H, Kaur, M J, Mitchinson, B, Halliwell   +3 more
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Quantitative Proteome Mapping of Nitrotyrosines

2008
An essential first step in the understanding disease and environmental perturbations is the early and quantitative detection of the increased levels of the inflammatory marker nitrotyrosine, as compared with its endogenous levels within the tissue or cellular proteome.
Diana J, Bigelow, Wei-Jun, Qian
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Anti-Nitrotyrosine Antibodies for Immunohistochemistry

2003
Nitrotyrosine is an important marker for the formation of peroxynitrite and possibly other reactive nitrogen species derived from nitric oxide in vivo (1). Pathological conditions can substantially increase the production of nitric oxide, yet this molecule itself does not generally yield nitration of tyrosine residues in proteins when added to ...
L, Viera, Y Z, Ye, J S, Beckman
openaire   +2 more sources