General practitioners' perspectives on diagnosis and treatment of uncomplicated urinary tract infections: A qualitative study in the Northern Dutch-German cross-border region. [PDF]
Bedri A +7 more
europepmc +1 more source
Antibiotic resistance of urinary pathogens after kidney transplantation: a 10-year single-center survey in Germany. [PDF]
Weber P +12 more
europepmc +1 more source
Decoding antibiotic modes of action from multimodal cellular responses
Sieber S +6 more
europepmc +1 more source
One-step drug transport across two membranes of Gram-negative bacteria by an MFS tripartite assembly
Luisi B +15 more
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Antifungal activity of nitroxoline against Candida auris isolates [PDF]
To investigate the in vitro activity of nitroxoline against a molecularly characterized collection of clinical Candida auris isolates.Thirty-five clinical isolates of C. auris from diverse sources representing all five different C. auris clades were included in the study. Nitroxoline activity was assessed using broth microdilution.
Frieder Fuchs +2 more
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Antimicrobial activity of clioquinol and nitroxoline: a scoping review
Clioquinol and nitroxoline, two drugs with numerous pharmacological properties fallen into disuse for many decades. The first was considered dangerous due to contraindications and the second mainly because was taken as ineffective, despite its known antibacterial activity. In the last decades, the advances in pharmaceutical chemistry, molecular biology,
Saulo Andrade +2 more
exaly +3 more sources
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Analysis of pharmacopoeia nitroxoline
Pharmaceutical Chemistry Journal, 1978I I Dozorova, V G Voronin, Voronin V G
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Repurposing of Nitroxoline Drug for the Prevention of Neurodegeneration
Chemical Research in Toxicology, 2019Oxidative stress has been documented as one of the significant causes of neurodegenerative diseases. Therefore, antioxidant therapy for the prevention of neurodegenerative diseases seems to be an interesting strategy in drug discovery. The quinoline-based compound, namely 5-nitro-8-quinolinol (NQ), has shown excellent antimicrobial, anticancer, and ...
Truong Van Hau +8 more
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Antibacterial and Antifungal Activities of Nitroxoline Mannich Bases
Chemotherapy, 2009The in vitro activity of nitroxoline and its Mannich bases against bacteria and fungi was investigated. Nitroxoline and its derivative with diisopropylamine as an amino component, exhibited the highest antimicrobial activity. The optimum hydro/lipophilic properties (log P), both for antibacterial and antifungal activity, are about log P values of 2 ...
Medić-Šarić, Marica +3 more
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