Results 31 to 40 of about 113,543 (162)

Genomic Variant in NK-Lysin Gene Is Associated with T Lymphocyte Subpopulations in Pigs. [PDF]

Genes (Basel), 2022
As an antimicrobial peptide, NK-lysin (NKL) plays an important role in the innate immune system of organisms. In this study, 300 piglets (68 Landrace pigs, 158 Large White pigs and 74 Songliao Black pigs) were used to further explore the function of NLK gene in porcine immune system.
Tong S, Shi N, Zheng K, Yin Z, Zhang X, Liu Y.   +5 more
europepmc   +3 more sources

A Non-Canonical Teleost NK-Lysin: Antimicrobial Activity via Multiple Mechanisms. [PDF]

Int J Mol Sci, 2022
NK-lysin (NKL) is a family of antimicrobial proteins with an important role in innate and adaptive immunity. In this study, a non-canonical NK-lysin (NKLnc) was identified in the Japanese flounder (Paralichthys olivaceus), which shares low sequence identities (15.8–20.6%) with previously reported fish NKLs and was phylogenetically separated from the ...
Xu H, Yuan Z, Sun L.
europepmc   +3 more sources

Effects of Dietary Clostridium butyricum on Growth and Intestinal Mucosal Barrier Functions of Juvenile Channel Catfish (Ictalurus punctatus) [PDF]

Microorganisms
An 8-week feeding trial was conducted to investigate the effects of dietary Clostridium butyricum on the growth and intestinal mucosal barrier functions of juvenile channel catfish (Ictalurus punctatus).
Zihe Guo, Ye Qian, Xiao Peng, Chanxia Qin, Huige Ren, Jingyi Du, Chengrui Huang, Mingzhu Pan, Weihao Ou   +8 more
doaj   +2 more sources

Expression of Chicken NK-Lysin and Its Role in Chicken Coccidiosis Induced by Eimeria necatrix. [PDF]

Korean J Parasitol, 2021
Coccidiosis in chickens is an intestinal parasitic disease caused by protozoan parasites named Eimeria spp. In some Eimeria infections, intestinal lymphocytes are known to highly express chicken NK-lysin (cNK-lysin), an antimicrobial peptide with anticoccidial activity.
Kim WH, Min W, Park KI, Lillehoj HS, Fernandez-Colorado CP, Flores RA, Cammayo PLT, Nguyen BT.   +7 more
europepmc   +4 more sources

Conserved structure and function in the granulysin and NK-lysin peptide family. [PDF]

Infect Immun, 2005
ABSTRACTGranulysin and NK-lysin are homologous bactericidal proteins with a moderate residue identity (35%), both of which have antimycobacterial activity. Short loop peptides derived from the antimycobacterial domains of granulysin, NK-lysin, and a putative chicken NK-lysin were examined and shown to have comparable antimycobacterial but ...
Linde CM, Grundström S, Nordling E, Refai E, Brennan PJ, Andersson M.   +5 more
europepmc   +4 more sources

Characterization of Bovine Homologues of Granulysin and NK-lysin [PDF]

The Journal of Immunology, 2004
Abstract Granulysin and NK-lysin are antimicrobial proteins found in the granules of human and swine cytotoxic lymphocytes. A murine counterpart to granulysin has not been identified to date, indicating the importance of additional models to fully characterize the role of granulysin-like molecules in the immune response to infectious ...
Janice J, Endsley, Jason L, Furrer, Mark A, Endsley, Mark A, McIntosh, Alexander C, Maue, W Ray, Waters, David R, Lee, D Mark, Estes   +7 more
openaire   +2 more sources

Molecular identification and bactericidal function analysis of NK-lysin from black sea bass (Centropristis striata)

Aquaculture Reports, 2023
NK-lysin is a component of natural killer cells and cytotoxic T lymphocytes, and it plays an important role in the innate immune response of aquatic animals against various pathogens.
Xiaowan Ma, Yongze Xing, Hongtao Liu, Dewei Cheng, Xuyang Chen, Ying Qiao, Shengping Zhong   +6 more
doaj   +1 more source

Design, Expression and Evaluation of Bacteriostatic Activity of Hybrid Antimicrobial Peptide NK-LPd

Shipin gongye ke-ji, 2023
Objective: To reveal the bacteriostatic activity of hybrid antimicrobial peptide NK-LPd, and discuss its further exploitation potential. Methods: Two glycines were utilized as the linker to connect the active fragments of NK-lysin and Piscidin, and the ...
Ziqi LIU, Zhengyu LIU, Yinhong GUO, Hongfei WANG, Bo YAO   +4 more
doaj   +1 more source

Interaction of NK Lysin, a Peptide Produced by Cytolytic Lymphocytes, with Endotoxin [PDF]

Infection and Immunity, 1999
ABSTRACTNK lysin is a 9-kDa polypeptide that was originally isolated from porcine intestinal tissue based on its antibacterial activity. It is produced by cytolytic lymphocytes and is cytolytic against a number of different types of tumor cells. Here we report the binding of NK lysin to lipopolysaccharide (LPS) and its anti-LPS activity. NK lysin binds
M, Andersson, R, Girard, P, Cazenave
openaire   +2 more sources

Orally delivered Bacillus subtilis expressing chicken NK-2 peptide stabilizes gut microbiota and enhances intestinal health and local immunity in coccidiosis-infected broiler chickens

Poultry Science, 2023
: We recently reported a stable Bacillus subtilis-carrying chicken NK-lysin peptide (B. subtilis-cNK-2) as an effective oral delivery system of an antimicrobial peptide to the gut with therapeutic effect against Eimeria parasites in broiler chickens.
Samiru S. Wickramasuriya, Inkyung Park, Youngsub Lee, Luciana M. Richer, Chris Przybyszewski, Cyril G. Gay, Jolieke G. van Oosterwijk, Hyun S. Lillehoj   +7 more
doaj   +1 more source