Results 161 to 170 of about 582,983 (289)

Multiphysics‐Driven Assembly of Biomimetic Vesicles

Advanced Materials, EarlyView.
Artificial extracellular vesicles, derived from cell membranes, are manufactured using a multiphysics‐integrated microfluidic platform that combines nanoknife membrane rupture, herringbone chaotic mixing, and acoustothermal modulation. This standardizable workflow enables the predictable control of vesicle formation and therapeutic loading, while ...
Timofei Solodko, Ian Gimino, Aastha Chandiwala, Bayan Alkotoub, Ali Bashiri Dezfouli, Heiko Reith, Asjad Bakhtiar, Rojda Hicsanmaz, Johann Brenner, Christoph J. O. Kaiser, Elena Belli, Shilpi Pandey, Samuel D. Rabkin, Kornelius Nielsch, Gabriele Multhoff, Oliver Hayden, Morteza Hasanzadeh Kafshgari   +16 more
wiley   +1 more source

Intra-tumoral NK cells and their association with patient outcomes: a novel prognostic model incorporating NK cells and clinicopathologic features in gastric cancer. [PDF]

Front Immunol
Oshi M, Tamura Y, Wu R, Rog CJ, Yan L, Yuza K, Kosaka T, Akiyama H, Ishikawa T, Takabe K, Endo I.   +10 more
europepmc   +1 more source

Breaking the 2‐nm Barrier in Hard Disk Drives Using Monolayer Amorphous Carbon Overcoats

Advanced Materials, EarlyView.
The rapid growth of AI has increased demand for large‐scale data storage, making HDDs indispensable in data centers. Increasing areal storage density is crucial, but limited by the traditional carbon overcoats (COC). Monolayer amorphous carbon (MAC) offers a superior alternative.
Hongji Zhang, Artem K. Grebenko, Dmitrii Litvinov, Wenwen Zheng, Konstantin V. Iakoubovskii, Sergey Y. Grebenchuk, Anna Makarova, Alexander Fedorov, Andrei Starkov, Carlo M. Orofeo, Denis V. Vyalikh, Mario Lanza, Maciej Koperski, Kostya S. Novoselov, Chee‐Tat Toh, Barbaros Ӧzyilmaz   +15 more
wiley   +1 more source

NK cells in HPV-related tumorigenesis: mechanisms and clinical applications. [PDF]

Front Cell Infect Microbiol
Deng J, Liu Y, Ma X, Li D, Li Z, Pan Y, Zeng X.   +6 more
europepmc   +1 more source

Cholesterol‐DNA Origami Nanostructures for Synthetic Lipid Rafts Induce Early T Cell Activation Signals

Advanced Materials Interfaces, EarlyView.
Here, we present a nanotechnology approach to construct synthetic lipid rafts on the live T cell membrane, leveraging a versatile DNA origami‐enabled platform named as the “cholesterol nano‐patch” (CNP). Our investigation highlights the effectiveness of DNA nanotechnology in exploring the impact of nanoscale arrangement of cholesterols on the ...
Yunmin Jung, Young‐Joo Kim, Kunwoo Noh, Sunmi Lee, Minsuk Kwak   +4 more
wiley   +1 more source

A Novel MICB-Targeting CAR-NK Cells for the Treatment of Pancreatic Cancer. [PDF]

Int J Mol Sci
Jin W, Wang M, Wang J, Fan J, Fang J, Yang G.   +5 more
europepmc   +1 more source

[Natural killer (NK) cells].

Lijecnicki vjesnik, 1984
Prirođeno ubilačke (NK ...
openaire   +2 more sources

Mitochondria‐Specific Protein Delivery by Protease‐Triggered Release in Plants with Single‐Walled Carbon Nanotubes

Advanced Materials Technologies, EarlyView.
Polymer‐coated carbon nanotubes were engineered as protease‐responsive nanocarriers for protein delivery in intact plants. GFP cargo can be released by cytosolic phytaspase cleavage and subsequently targeted to mitochondria via an N‐terminal sequence, enabling controlled intracellular protein delivery without tissue damage and demonstrating stable ...
Simon Sau Yin Law, Takehiro Suzuki, Tsuyohiko Fujigaya, Keiji Numata   +3 more
wiley   +1 more source

Engineering immunity with CAR-NK cells: advancing the frontiers of cancer immunotherapy. [PDF]

Front Pharmacol
Cianga VA, Antohe I, Minciună C, Dăscălescu A.   +3 more
europepmc   +1 more source

Perfusion Bioreactor Culture Incorporating Mechanical Confinement Enhances Mesenchymal Stem Cell Extracellular Vesicle Production and Wound Healing Potential

Advanced Materials Technologies, EarlyView.
Scalable manufacturing challenges and limited potency remain two of the most intransigent issues limiting clinical translation of EV therapeutics. Mechanical cues can induce phenotypic changes and increased vesiculation in EV source cells without the use of extraneous reagents, chemicals, and/or cargo, thereby potentially drastically improving the ...
Emily H. Powsner, Raith Nowak, Stephanie M. Kronstadt, Nicholas H. Pirolli, Talia J. Solomon, Kristin Nikolov, William Pieper Holeman, Ian M. Smith, Kimberly M. Stroka, John P. Fisher, Steven M. Jay   +10 more
wiley   +1 more source